The effect of adrenal steroids on electrolyte excretion.

The regulation of water and electrolyte metabolism has been the subject of much investigation. Many factors have been implicated, one being that volume plays a role in the regulation of sodium in the body. It has been suggested that there may be receptors somewhere in the body, which are sensitive to changes in the volume of fluid or in the concentration of electrolytes. It has not been clearly established yet whether they are sensitive to blood volume, plasma colloid osmotic pressure, interstitial fluid volume, or some other factor. The importance of the adrenal cortex in influencing sodium metabolism is well established

The effect of adrenal cortical hormones on electrolyte excretion.

The importance of tile adrenal cortex in influencing sodium and potassium metabolism is well established. The adrenal cortex secretes a number of steroid hormones which affect sodium and potassium excretion to varying degrees. The hormone which is the most potent in its sodium retaining effect is aldosterone. It promotes the sodium reabsorption for the exchange of potassium or hydrogen ion in the distal tubules of the kidney. There are several problems which are not well understood, e.g. the physiological importance of the rate of secretion of various steroids, the synergistic or antagonistic action of various adrenal cortical hormones on the absorption, distribution and excretion of electrolyte and their interplay with each other

Comparison of Substrates for Measuring Serum Choline Esterase Activity in Hepato-Biliary Disease

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