Timetable of Gait Cycle Events in Parkinson's Disease.

The study used an algorithmic method to measure fluctuations in the timetable of gait cycle events in patients with Parkinson's disease (PD). Subjects with severe PD (n=10; age 63.6 ± 10.1 years; Hoehn & Yahr [H & Y] disability score 3 or 4), mild PD (n=10; age 65.5 ± 4.3; H & Y ≦ 2), and normal controls (n=10; age 65.1 ± 13.3) were studied. A camera was mounted on the trunk, and the subjects walked in a self-selected manner. Overhead images of the foot path were analyzed to geometrically describe motion in terms of displacement and velocity. The timing of three gait events, i.e.,¹⁾ feet adjacent,²⁾ maximum speed of swinging foot, and³⁾ the trunk climbing to its highest point in mid-stance, was determined for extracted steps during steady-state gait. In severe PD, 74.9 ± 21.7% of steps was timetabled so that the swinging leg and the stance-phase leg became side by side before the trunk rose to its highest point to achieve 'foot clearance'. This pattern was significantly less prevalent in mild PD and controls. An altered timetable of gait cycle events may provide quantitative indices of gait disability during steady-state walking in patients with PD

Nightmare-Enacting Behavior Responding to Zonisamide in Early Parkinson's Disease

Recently, zonisamide (ZNS) has been approved as a new adjunctive therapy for motor complications of Parkinson's disease (PD). More recently, ZNS was reported to be effective for the management of impulse control behavior in PD, suggesting potential effects on non-motor PD symptoms. Dream enactment associated with aggressive, violent behavior can carry a serious risk of injury to patients, as well as to spouses or caretakers. This report describes a patient with PD who had vivid nightmares and dream-enacting behavior that resolved after treatment with ZNS. The present case raises the question whether ZNS might potentially be effective for the management of vivid nightmares or dream-enacting behavior

On the structures of moss colony in the Yukidori Valley, Langhovde, East Antarctica

The moss vegetation developing in the Yukidori Valley, Langhovde, East Antarctica, was investigated as based on the samples in the vertical cross-section housed as the herbarium specimens to categorize the structure of the moss colony and to determine the specific composition. The vegetation consists of pure colonies of one species, and mixed colonies composed of two or rarely three moss species. Each colony was classified by species composition and degree of unevenness. The active zone, decomposed zone which were seen in the vertical cross-section, and epiphytic condition on the surface such as cyanobacteria and imperfect lichens, and rhizoidal layers in the inside of colony were determined and measured. Furthermore, the relationship between epiphytic condition and the thickness of the pure and mixed colonies was discussed taking account of ecological significances of these structural features

Observations of Chromospheric Anemone Jets with Hinode SOT and Hida Ca II Spectroheliogram

We present the first simultaneous observations of chromospheric "anemone" jets in solar active regions with Hinode SOT Ca II H broadband filetergram and Ca II K spetroheliogram on the Domeless Solar Telescope (DST) at Hida Observatory. During the coordinated observation, 9 chromospheric anemone jets were simultaneously observed with the two instruments. These observations revealed three important features, i.e.: (1) the jets are generated in the lower chromosphere, (2) the length and lifetime of the jets are 0.4-5 Mm and 40-320 sec, (3) the apparent velocity of the jets with Hinode SOT are 3-24 km/s, while Ca II K3 component at the jets show blueshifts (in 5 events) in the range of 2- 6 km/s. The chromospheric anemone jets are associated with mixed polarity regions which are either small emerging flux regions or moving magnetic features. It is found that the Ca II K line often show red or blue asymmetry in K2/K1 component: the footpoint of the jets associated with emerging flux regions often show redshift (2-16 km/s), while the one with moving magnetic features show blueshift (around 5 km/s). Detailed analysis of magnetic evolution of the jet foaming regions revealed that the reconnection rate (or canceling rate) of the total magnetic flux at the footpoint of the jets are of order of 10^{16} Mx/s, and the resulting magnetic energy release rate (1.1-10) x 10^{24} erg/s, with the total energy release (1-13) x 10^{26} erg for the duration of the magnetic cancellations, 130s. These are comparable to the estimated total energy, 10^{26} erg, in a single chromospheric anemone jet. An observation-based physical model of the jet is presented. The relation between chromospheric anemone jets and Ellerman bombs is discussed.Comment: 22 pages, 27 figures, accepted for Publications of the Astronomical Society of Japa

A survey of T Tauri stars with AKARI toward the Taurus-Auriga region

Aims: We search new T Tauri star (TTS) candidates with the mid-infrared (MIR) part of the AKARI All-Sky Survey at 9 and 18 um wavelengths. Methods: We used the point source catalogue (PSC), obtained by the Infrared Camera (IRC) on board AKARI. We combined the 2MASS PSC and the 3rd version of the USNO CCD Astrograph Catalogue (UCAC) with the AKARI IRC-PSC, and surveyed 517 known TTSs over a 1800-square-degree part of the Taurus-Auriga region to find criteria to extract TTSs. We considered asymptotic giant branch (AGB) stars, post-AGB stars, Planetary Nebulae (PNe), and galaxies, which have similar MIR colours, to separate TTSs from these sources. Results: Of the 517 known TTSs, we detected 133 sources with AKARI. Based on the colour-colour and colour-magnitude diagrams made from the AKARI, 2MASS, and UCAC surveys, we propose the criteria to extract TTS candidates from the AKARI All-Sky data. On the basis of our criteria, we selected 176/14725 AKARI sources as TTS candidates which are located around the Taurus-Auriga region. Comparing these sources with SIMBAD, there are 148 previously identified sources including 115 Young Stellar Objects (YSOs), and 28 unidentified sources. Conclusions: Based on SIMBAD identifications, we take the TTS-identification probability using our criteria to be ~75 %. We find 28 TTS candidates, of which we expect 21 to be confirmed once follow-up observations can be obtained. Although the probability of ~75 % is not so high, it is affected by the completeness of the SIMBAD database, and we can search for TTSs over the whole sky, over all star forming regions.Comment: 12 pages, 9 figures, accepted for publication in A&

Strontium-mediated selective protonation of unsaturated linkage of aromatic hydrocarbons and these derivatives

The selective protonation of aromatic hydrocarbons with at least two or more aromatic rings and aromatic compounds bearing unsaturated linkages can be achieved by metallic strontium metal with ammonium chloride and iodine, or ammonium iodide in tetrahydrofuran. The reaction system is ammonia-free in room temperature and the reaction proceeds high selectivity in moderate to good yields

H2O maser motions and the distance of the star forming region G192.16-3.84

We present the results of astrometic observations of H2O masers associated with the star forming region G192.16-3.84 with the VLBI Exploration of Radio Astrometry (VERA). The H2O masers seem to be associated with two young stellar objects (YSOs) separated by \sim1200 AU as reported in previous observations. In the present observations, we successfully detected an annual parallax of 0.66 \pm 0.04 mas for the H2 O masers, which corresponds to a distance to G192.16-3.84 of D = 1.52 \pm 0.08 kpc from the Sun. The determined distance is shorter than the estimated kinematic distance. Using the annual parallax distance and the estimated parameters of the millimeter continuum emission, we estimate the mass of the disk plus circumstellar cloud in the southern young stellar object to be 10.0+4.3M\cdot. We also estimate the galactocentric distance and the peculiar motion -3.6 of G192.16-3.84, relative to a circular Galactic rotation: R\star = 9.99 \pm 0.08 kpc, Z\star = -0.10 \pm 0.01 kpc, and (U\star,V\star,W\star)=(-2.8\pm1.0,-10.5\pm0.3,4.9\pm2.7)[kms-1]respectively. The peculiar motion of G192.16-3.84 is within that typically found in recent VLBI astrometric results. The angular distribution and three-dimensional velocity field of H2O maser features associated with the northern YSO indicate the existence of a bipolar outflow with a major axis along the northeast-southwest direction.Comment: 9 pages, 2 figures and 4 tables. Accepted for publication on PAS