Magnetic-Field Induced Gap in One-Dimensional Antiferromagnet KCuGaF6_6

Magnetic susceptibility and specific heat measurements in magnetic fields were performed on an $S=1/2$ one-dimensional antiferromagnet KCuGaF$_6$. Exchange interaction was evaluated as $J/k_{\rm B}\simeq 100$ K. However, no magnetic ordering was observed down to 0.46 K. It was found that an applied magnetic field induces a staggered magnetic susceptibility obeying the Curie law and an excitation gap, both of which should be attributed to the antisymmetric interaction of the Dzyaloshinsky-Moriya type and/or the staggered $g$-tensor. With increasing magnetic field $H$, the gap increases almost in proportion to $H^{2/3}$.Comment: Submitted to Proceedings of Research in High Magnetic Fiel

Partial ferromagnetic ordering and indirect exchange interaction in spatially anisotropic kagome antiferromagnet Cs_2Cu_3CeF_{12}

We report the crystal structure and unconventional magnetic ordering of Cs_2Cu_3CeF_{12}, which is composed of buckled kagome lattice of Cu^{2+} ions. The exchange network in the buckled kagome lattice is fairly anisotropic, so that the present spin system can be divided into two subsystems: alternating Heisenberg chains with strong antiferromagnetic exchange interactions and dangling spins. Although the direct exchange interactions between neighboring spins were found to be all antiferromagnetic, ferromagnetic magnetic ordering of the dangling spins was observed. Magnetization exhibits a plateau at one-third of the saturation magnetization. These observations can be understood in terms of the indirect interaction between dangling spins mediated by the chain spin.Comment: 4 pages, 3 figure

Benign giant mediastinal schwannoma presenting as cardiac tamponade in a woman: a case report

<p>Abstract</p> <p>Introduction</p> <p>Mediastinal schwannomas are typically benign and asymptomatic, and generally present no immediate risks. We encountered a rare case of a giant benign posterior mediastinal schwannoma, complicated by life-threatening cardiac tamponade.</p> <p>Case presentation</p> <p>We report the case of a 72-year-old Japanese woman, who presented with cardiogenic shock. Computed tomography of the chest revealed a posterior mediastinal mass 150 cm in diameter, with pericardial effusion. The cardiac tamponade was treated with prompt pericardial fluid drainage. A biopsy was taken from the mass, and after histological examination, it was diagnosed as a benign schwannoma, a well-encapsulated non-infiltrating tumor, originating from the intrathoracic vagus nerve. It was successfully excised, restoring normal cardiac function.</p> <p>Conclusion</p> <p>Our case suggests that giant mediastinal schwannomas, although generally benign and asymptomatic, should be excised upon discovery to prevent the development of life-threatening cardiopulmonary complications.</p

SiC Nanorods Grown on Electrospun Nanofibers Using Tb as Catalyst: Fabrication, Characterization, and Photoluminescence Properties

Well-crystallizedβ-SiC nanorods grown on electrospun nanofibers were synthesized by carbothermal reduction of Tb doped SiO2(SiO2:Tb) nanofibers at 1,250 °C. The as-synthesized SiC nanorods were 100–300 nm in diameter and 2–3 μm in length. Scanning electron microscopy (SEM) results suggested that the growth of the SiC nanorods should be governed by vapor-liquid-solid (VLS) mechanism with Tb metal as catalyst. Tb(NO3)3particles on the surface of the electrospun nanofibers were decomposed at 500 °C and later reduced to the formation of Tb nanoclusters at 1,200 °C, and finally the formation of a Si–C–Tb ally droplet will stimulate the VLS growth at 1,250 °C. Microstructure of the nanorod was further investigated by transmission electron microscopy (TEM). It was found that SiC <111> is the preferred initial growth direction. The liquid droplet was identified to be Si86Tb14, which acted as effective catalyst. Strong green emissions were observed from the SiC nanorod samples. Four characteristic photoluminescence (PL) peaks of Tb ions were also identified

Alternative signaling network activation through different insulin receptor family members caused by pro-mitogenic antidiabetic insulin analogues in human mammary epithelial cells

INTRODUCTION: Insulin analogues are designed to have improved pharmacokinetic parameters compared to regular human insulin. This provides a sustained control of blood glucose levels in diabetic patients. All novel insulin analogues are tested for their mitogenic side effects, however these assays do not take into account the molecular mode of action of different insulin analogues. Insulin analogues can bind the insulin receptor and the insulin-like growth factor 1 receptor with different affinities and consequently will activate different downstream signaling pathways. METHODS: Here we used a panel of MCF7 human breast cancer cell lines that selectively express either one of the isoforms of the INSR or the IGF1R. We applied a transcriptomics approach to assess the differential transcriptional programs activated in these cells by either insulin, IGF1 or X10 treatment. RESULTS: Based on the differentially expressed genes between insulin versus IGF1 and X10 treatment, we retrieved a mitogenic classifier gene set. Validation by RT-qPCR confirmed the robustness of this gene set. The translational potential of these mitogenic classifier genes was examined in primary human mammary cells and in mammary gland tissue of mice in an in vivo model. The predictive power of the classifier genes was evaluated by testing all commercial insulin analogues in the in vitro model and defined X10 and glargine as the most potent mitogenic insulin analogues. CONCLUSIONS: We propose that these mitogenic classifier genes can be used to test the mitogenic potential of novel insulin analogues as well as other alternative molecules with an anticipated affinity for the IGF1R. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13058-015-0600-5) contains supplementary material, which is available to authorized users

Inhibition of connexin 43 expression and function in cultured rat dental pulp cells by antisense oligonucleotide

博士（歯学）・第1700号（乙第717号）・平成18年12月13