40 research outputs found
Probing Non-Standard Neutrino Interactions with Neutrino Factories
We discuss the sensitivity reach of a neutrino factory measurement to
non-standard neutrino interactions (NSI), which may exist as a low-energy
manifestation of physics beyond the Standard Model. We use the muon appearance
mode \nu_e --> \nu_\mu and consider two detectors, one at 3000 km and the other
at 7000 km.
Assuming the effects of NSI at the production and the detection are
negligible, we discuss the sensitivities to NSI and the simultaneous
determination of \theta_{13} and \delta by examining the effects in the
neutrino propagation of various systems in which two NSI parameters
\epsilon_{\alpha \beta} are switched on. The sensitivities to off-diagonal
\epsilon's are found to be excellent up to small values of \theta_{13}.
We demonstrate that the two-detector setting is powerful enough to resolve
the \theta_{13}-NSI confusion problem. We believe that the results obtained in
this paper open the door to the possibility of using neutrino factory as a
discovery machine for NSI while keeping its primary function of performing
precision measurements of the lepton mixing parameters.Comment: 47 pages, 22 figures. Color version of Figs. 18, 19 and 22 can be
found in the article published in JHE
Recoilless Resonant Absorption of Monochromatic Neutrino Beam for Measuring Delta m^2_{31} and theta_{13}
We discuss, in the context of precision measurement of Delta m^2_{31} and
theta_{13}, physics capabilities enabled by the recoilless resonant absorption
of monochromatic antineutrino beam enhanced by the M\"ossbauer effect recently
proposed by Raghavan. Under the assumption of small relative systematic error
of a few tenth of percent level between measurement at different detector
locations, we give analytical and numerical estimates of the sensitivities to
Delta m^2_{31} and sin^2 2theta_{13}. The accuracies of determination of them
are enormous; The fractional uncertainty in Delta m^2_{31} achievable by 10
point measurement is 0.6% (2.4%) for sin^2 2theta_{13} = 0.05, and the
uncertainty of sin^2 2theta_{13} is 0.002 (0.008) both at 1 sigma CL with the
optimistic (pessimistic) assumption of systematic error of 0.2% (1%). The
former opens a new possibility of determining the neutrino mass hierarchy by
comparing the measured value of Delta m^2_{31} with the one by accelerator
experiments, while the latter will help resolving the theta_{23} octant
degeneracy.Comment: 23 pages, 3 figures, version to appear in New Journal of Physic
Isquemia hepĂĄtica normotĂ©rmica em ratos: estudo da lesĂŁo celular atravĂ©s do uso de clampeamento pedicular contĂnuo e intermitente
Embryonic mesothelial-derived hepatic lineage of quiescent and heterogenous scar-orchestrating cells defined but suppressed by WT1
Differential effects of hyaluronan synthase 3 deficiency after acute vs chronic liver injury in mice
Domino compensation of the external iliac vein using an ePTFE graft after its procurement for portal vein reconstruction in pancreatic surgery
Domino compensation of the external iliac vein using an ePTFE graft after its procurement for portal vein reconstruction in pancreatic surgery
Impact of organ motion on volumetric and dosimetric parameters in stomach lymphomas treated with intensity-modulated radiotherapy
Purpose Interplay effects may influence dose distributions to a moving target when using dynamic delivery techniques such as intensity-modulated radiotherapy (IMRT). The aim of this study was to evaluate the impact of organ motion on volumetric and dosimetric parameters in stomach lymphomas treated with IMRT. Methods Ten patients who had been treated with IMRT for stomach lymphomas were enrolled. The clinical target volume (CTV) was contoured as the whole stomach. Considering interfractional uncertainty, the internal target volume (ITV) margin was uniformly 1.5 cm to the CTV and then modified based on the 4DCT images in case of the large respiratory motion. The planning target volume (PTV) was created by adding 5 mm to the ITV. The impact of organ motion on the volumetric and dosimetric parameters was evaluated retrospectively (4D simulation). The organ motion was reproduced by shifting the isocenter on the radiation treatment planning system. Several simulation plans were created to test the influence of the beam-on timing in the respiration cycle on the dose distribution. The homogeneity index (HI), volume percentage of stomach covered by the prescribed dose (V-p), and D-99 of the CTV were evaluated. Results The organ motion was the largest in the superior-inferior direction (10.1 +/- 4.5 mm [average +/- SD]). Stomach volume in each respiratory phase compared to the mean volume varied approximately within a +/- 5% range in most of the patients. The PTV margin was sufficiently large to cover the CTV during the IMRT. There was a significant reduction in V-p and D-99 but not in HI in the 4D simulation in free-breathing and multiple fractions compared to the clinically-used plan (P < 0.05) suggesting that interplay effects deteriorate the dose distribution. The absolute difference of D-99 was less than 1% of the prescribed dose. Conclusions There were significant interplay effects affecting the dose distribution in stomach IMRT. The magnitude of the dose reduction was small when patients were treated on free-breathing and multiple fractions