The effect of Treculia africana African breadfruit on serum electrolyte enzyme and some haematological parameter in rat: a sub-chronic study

A sub-chronic effect of diet of Treculia africana (Bread fruit BF) on serum electrolyte, enzyme and some haematological parameters in rats was studied. The test-diets were administered for 21 days after which, serum electrolyte enzyme and heamatological parameters were assayed. The control group were similarly treated but given normal diet The result showed that serum sodium (Na+) of rats given bread fruit diet of 10% and 20% respectively were significantly (

An appraisal of the ‘Publish or Perish\' mantra in tertiary institutions

No Abstract. SOPHIA: An African Journal of Philosphy and Public Affairs Vol. 10 (1) 2007: pp. 196-20

Vitamin b12 supplementation: effects on some biochemical and haematological indices of rats on phenytoin administration

Phenytoin is known to have some toxicological implications. Vitamin B12 supplementation during phenytoin administration was investigated to assess the benefits and risks of single vitamin supplementation. This study evaluated the biochemical and haematological effects of vitamin B12 on phenytoin toxicity. Twenty-four experimental animals were divided into 3 groups of 8 rats each. The control (group 1) received distilled water as placebo. Groups 2 and 3 were given 5mg/kg body weight of phenytoin for 4 weeks while group 3 in addition tophenytoin received intra-peritoneal administration of 15g/kg body of vitamin B12 twice a week. Biochemical parameters such as AST, ALT, ALP, lipid profile and haematological indices were assayed as indices of toxicity. The result of the study showed that phenytoin administration resulted in anaemia which was ameliorated by vitaminB12 co-administration. Phenytoin also increased significantly the leukocyte count upon which B12 had no effect. Liver enzymes activities were significantly (

Vernonia amygdalina Del: A potential prophylactic anti-diabetic agent in lipid complication

No Abstract.Global Journal of Pure and Applied Sciences Vol. 13 (1) 2007: pp. 103-10

Effect Of Inhalation Exposure To Kerosene And Petrol-Fumes On Some Anaemia-Diagnostic Indices In Rats

Changes in total body weight, some anaemia-diagnostic indices (haematocrit or packed cell volume (PCV), haemoglobin (Hb) and total serum protein) were determined in rats (Wistar albino strain) after 2 weeks of 4 hours daily inhalation exposure to ungraded concentrations of kerosene and petrol fumes. The results obtained for those rats exposed to petrol and kerosene fumes showed a significant decrease (