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Powder Compaction: Compression Properties of Cellulose Ethers

Author: Adams M., Mullier, M. & Seville, J.
Adolfsson Å. & Nyström, C.
Adolfsson Å., Caramella, C. & Nyström, C.
Adolfsson Å., Gustafsson, C. & Nyström, C.
Adolfsson Å., Olsson, H. & Nyström, C.
Ahlneck C. & Alderborn, G.
Alderman D. A.
Alvarez-Lorenzo C., Gomez-Amoza, J. L., Martınez-Pacheco, R., Souto, C., & Concheiro, A.
Asare-Addo K., Kaialy, W., Levina, M., Rajabi-Siahboomi, A., Ghori, M. U., Supuk, E., Laity, P.R., Conway, B.R. & Nokhodchi, A.
Chebli C., & Cartilier, L.
Coffin-Beach D. P. & Gary Hollenbeck, R.
Crouter A. & Briens, L.
Dabbagh M. A., Ford, J. L., Rubinstein, M. H. & Hogan, J. E.
Desai D., Rinaldi, F., Kothari, S., Paruchuri, S., Li, D., Lai, M., Fung, S., & Both, D.
Desai R. P., Neau, S. H., Pather, S. I., & Johnston, T. P.
Duberg M. & Nyström, C.
Emeje M. O., Kunle, O. O., & Ofoefule, S. I.
Escudero J. J., Ferrero, C. & Jiménez-Castellanos, M. R.
Escudero J. J., Ferrero, C., Casas, M. & Jiménez-Castellanos, M. R.
Escudero J., Ferrero, C. & Jiménez-Castellanos, M.
Frenning G., Mahmoodi, F., Nordström, J. & Alderborn, G.
Ghori M. U., & Conway, B. R.
Ghori M. U., Ginting, G., Smith, A. M. & Conway, B. R.
Ghori M. U., Šupuk, E. & Conway, B. R.
Ghori M. U., Šupuk, E., & Conway, B. R.
Gustafsson C., Bonferoni, M. C., Caramella, C., Lennholm, H. & Nyström, C.
Heckel R.
Heckel R.
Hogan J. E.
Itiola O. A., & Pilpel, N.
Jivraj M., Martini, L. G. & Thomson, C. M.
Karehill P., Glazer, M. & Nyström, C.
Kawakita K. & Lüdde, K. H.
Kiekens F., Debunne, A., Vervaet, C., Baert, L., Vanhoutte, F., van assche, I., Menard, F. & Remon, J. P.
Kleinebudde P.
Leuenberger H.
Leuenberger H., Holman, L., Usteri, M. & Winzap, S.
Lordi N. & Shiromani, P.
Malamataris S. & Karidas, T.
Malamataris S., Karidas, T. & Goidas, P.
Maltais M., Vargas, R., & DiPaolo, T.
Mccormick D.
Melia C. D.
Mitchell S. A., Reynolds, T. D., & Dasbach, T. P.
Nep E. I., Asare-Addo, K., Ghori, M. U., Conway, B. R., & Smith, A. M.
Nokhodchi A. & Rubinstein, M. H.
Nokhodchi A., Ford, J. L., Rowe, P. H. & Rubinstein, M. H.
Nokhodchi A., Ford, J. L., Rowe, P. H. & Rubinstein, M. H.
Nokhodchi A., Ford, J. L., Rowe, P. H. & Rubinstein, M. H.
Nokhodchi A., Rubinstein, M. H. & Ford, J. L.
Nordström J., Welch, K., Frenning, G. & Alderborn, G.
Nyström C. & Karehill, P.G.
Nyström C., Alderborn, G., Duberg, M. & Karehill, P.G.
Patel S., Kaushal, A. M. & Bansal, A. K.
Patel S., Kaushal, A. M. & Bansal, A. K.
Picker-Freyer K. M., & Dürig, T.
Rajabi-Siahboomi A. R. & Nokhodchi, A.
Rajabi-Siahboomi A. R., Nokhodchi, A. & Rubinstein, M. H.
Roberts R., Rowe, R. & Kendall, K.
Rumpf H.
Selmeczi B., Kereszted, A., & Rapo, J.
Shokri J., & Adibkia, K.
Skinner G. W., Harcum, W. W., Barnum, P. E., & Guo, J. H.
Sonnergaard J.
Sun C. & Grant, D. J.
Turba E. & Rumpf, H.
Turkoglu M., Aydin, I., Murray, M., & Sakr, A.
Van Campen L., Zografi, G. & Carstensen, J.
York P.
Zografi G.
Šupuk E., Ghori, M. U., Asare-addo, K., Laity, P. R., Panchmatia, P. M. & Conway, B. R.
Publication venue: 'University of Huddersfield Press'
Publication date: 14/11/2016
Field of study

Effective development of matrix tablets requires a comprehensive understanding of different raw material attributes and their impact on process parameters. Cellulose ethers (CE) are the most commonly used pharmaceutical excipients in the fabrication of hydrophilic matrices. The innate good compression and binding properties of CE enable matrices to be prepared using economical direct compression (DC) techniques. However, DC is sensitive to raw material attributes, thus, impacting the compaction process. This article critically reviews prior knowledge on the mechanism of powder compaction and the compression properties of cellulose ethers, giving timely insight into new developments in this field

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