12,907 research outputs found

    The Portrayal of Complementary and Alternative Medicine in Mass Print Magazines Since 1980

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    Objectives: The objectives of this study were to examine and describe the portrayal of complementary and alternative medicine (CAM) in mass print media magazines. Design: The sample included all 37 articles found in magazines with circulation rates of greater than 1 million published in the United States and Canada from 1980 to 2005. The analysis was quantitative and qualitative and included investigation of both manifest and latent magazine story messages. Results: Manifest analysis noted that CAM was largely represented as a treatment for a patient with a medically diagnosed illness or specific symptoms. Discussions used biomedical terms such as patient rather than consumer and disease rather than wellness. Latent analysis revealed three themes: (1) CAMs were described as good but not good enough; (2) individualism and consumerism were venerated; and (3) questions of costs were raised in the context of confusion and ambivalence

    Shell Crossing Singularities in Quasi-Spherical Szekeres Models

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    We investigate the occurrence of shell crossing singularities in quasi-spherical Szekeres dust models with or without a cosmological constant. We study the conditions for shell crossing singularity both from physical and geometrical point of view and they are in agreement.Comment: 10 latex pages, RevTex style, no figure

    Meta-analysis of cognitive behaviour therapy and selective serotonin reuptake inhibitors for the treatment of hypochondriasis: Implications for trial design

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    Background: Classification of hypochondriasis as an obsessive-compulsive and related disorder in the International Classification of Diseases 11th Revision (ICD-11) has generated new heuristics for treatment of this common, chronic and disabling disorder. Standard treatment involves cognitive behaviour therapy (CBT) or selective serotonin reuptake inhibitors (SSRIs), but no meta-analysis has so far considered hypochondriasis as a structured diagnosis or assessed the role of medication. A clearer understanding of the relative effectiveness of these interventions and identification of clinically relevant factors moderating the treatment response is needed for clinical guideline development. Methods: The current systematic review and meta-analysis of interventions for hypochondriasis was preregistered on PROSPERO (CRD42020185768) and follows PRISMA guidelines. We searched MEDLINE, PsycINFO, and Cochrane Library databases until July 2021 for randomized controlled trials (RCTs) of interventions for patients diagnosed with hypochondriasis (or historical diagnostic equivalents). We assessed aspects of study quality using: the CONSORT Checklist for evaluation of RCTs, the Cochrane Risk of Bias 2 tool, researcher allegiance and treatment fidelity. The primary outcome was improvement in hypochondriasis symptoms, comparing intervention and control groups at trial endpoint. Moderator variables were assessed using subgroup and meta-regression analyses. Results: Searches identified 13 randomised controlled trials (RCTs) (N = 1405); 12 included CBT (N = 1212) and three included SSRI (N = 193) arms as the experimental intervention. Random effects meta-analysis yielded a moderate-to-large effect size for CBT versus all controls (g = −0.70 [95% CI -0.99 to −0.41], k = 18, I2 = 81.1%). Funnel plot asymmetry indicated possible publication bias and two potentially missing trials, reducing the effect size (g = −0.60 [95% CI -0.88 to −0.32]). Subgroup analysis showed that choice of control significantly moderated effect size, with those in CBT vs. wait-list (g = −1.32 [95% CI -1.75 to −0.90], k = 7, I2 = 0%) being double those of CBT vs. psychological or pharmacological placebo controls (g = −0.58 [95% CI -0.95 to −0.22], k = 7, I2 = 82%). Analysis of studies directly comparing CBT and SSRIs found a numerical, but not statistical advantage for SSRIs (g = 0.21 [95% CI -0.46 to 0.87], k = 2, I2 = 58.34%) and a modest effect size emerged for SSRIs vs. pill placebo (g = −0.29 [95% CI -0.57 to −0.01], k = 3, I2 = 0%). Most studies (11/13) were rated as high on potential researcher allegiance bias in favour of CBT. Meta-regressions revealed that effect sizes were larger in younger participants, and smaller in better quality and more recent RCTs and those with greater CBT fidelity. Conclusion: CBT and SSRIs are effective in the acute treatment of hypochondriasis, with some indication that intervention at a younger age produces better outcomes for CBT. In the case of CBT, effect sizes appear to have been significantly inflated by the use of wait list controls, and researcher allegiance bias. We recommend that a definitive, adequately controlled trial, designed with respect to the methodological issues raised in this meta-analysis, is needed to determine the magnitude effects for CBT and SSRIs with confidence and the long-term effect of treatments, to inform mental health service provision for this overlooked patient group

    The large amplitude outburst of the young star HBC 722 in NGC 7000/IC 5070, a new FU Orionis candidate

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    We report the discovery of a large amplitude outburst from the young star HBC 722 (LkHA 188 G4) located in the region of NGC 7000/IC 5070. On the basis of photometric and spectroscopic observations, we argue that this outburst is of the FU Orionis type. We gathered photometric and spectroscopic observations of the object both in the pre-outburst state and during a phase of increase in its brightness. The photometric BVRI data (Johnson-Cousins system) that we present were collected from April 2009 to September 2010. To facilitate transformation from instrumental measurements to the standard system, fifteen comparison stars in the field of HBC 722 were calibrated in the BVRI bands. Optical spectra of HBC 722 were obtained with the 1.3-m telescope of Skinakas Observatory (Crete, Greece) and the 0.6-m telescope of Schiaparelli Observatory in Varese (Italy). The pre-outburst photometric and spectroscopic observations of HBC 722 show both low amplitude photometric variations and an emission-line spectrum typical of T Tau stars. The observed outburst started before May 2010 and reached its maximum brightness in September 2010, with a recorded Delta V~4.7 mag. amplitude. Simultaneously with the increase in brightness the color indices changed significantly and the star became appreciably bluer. The light curve of HBC 722 during the period of rise in brightness is similar to the light curves of the classical FUors - FU Ori and V1057 Cyg. The spectral observations during the time of increase in brightness showed significant changes in both the profiles and intensity of the spectral lines. Only H alpha remained in emission, while the H beta, Na I 5890/5896, Mg I triplet 5174, and Ba II 5854/6497 lines were in strong absorption.Comment: 4 pages, 6 figures, accepted for publication in A&

    Strongly Correlated Fractional Quantum Hall Line Junctions

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    We have studied a clean finite-length line junction between interacting counterpropagating single-branch fractional-quantum-Hall edge channels. Exact solutions for low-lying excitations and transport properties are obtained when the two edges belong to quantum Hall systems with different filling factors and interact via the long-range Coulomb interaction. Charging effects due to the coupling to external edge-channel leads are fully taken into account. Conductances and power laws in the current-voltage characteristics of tunneling are strongly affected by inter-edge correlations.Comment: 4 pages, 1 figure, RevTex4, typos corrected + references added, to appear in Phys. Rev. Let

    Minimum-error discrimination between subsets of linearly dependent quantum states

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    A measurement strategy is developed for a new kind of hypothesis testing. It assigns, with minimum probability of error, the state of a quantum system to one or the other of two complementary subsets of a set of N given non-orthogonal quantum states occurring with given a priori probabilities. A general analytical solution is obtained for N states that are restricted to a two-dimensional subspace of the Hilbert space of the system. The result for the special case of three arbitrary but linearly dependent states is applied to a variety of sets of three states that are symmetric and equally probable. It is found that, in this case, the minimum error probability for distinguishing one of the states from the other two is only about half as large as the minimum error probability for distinguishing all three states individually.Comment: Representation improved and generalized, references added. Accepted as a Rapid Communication in Phys. Rev.

    Monte Carlo study of Si(111) homoepitaxy

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    An attempt is made to simulate the homoepitaxial growth of a Si(111) surface by the kinetic Monte Carlo method in which the standard Solid-on-Solid model and the planar model of the (7x7) surface reconstruction are used in combination. By taking account of surface reconstructions as well as atomic deposition and migrations, it is shown that the effect of a coorparative stacking transformation is necessary for a layer growth.Comment: 4 pages, 5 figures. For Fig.1 of this article, please see Fig.2 of Phys.Rev. B56, 3583 (1997). To appear in Phys.Rev.B. (June 1998

    Calculation of dephasing times in closed quantum dots

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    Dephasing of one-particle states in closed quantum dots is analyzed within the framework of random matrix theory and Master equation. Combination of this analysis with recent experiments on the magnetoconductance allows for the first time to evaluate the dephasing times of closed quantum dots. These dephasing times turn out to depend on the mean level spacing and to be significantly enhanced as compared with the case of open dots. Moreover, the experimental data available are consistent with the prediction that the dephasing of one-particle states in finite closed systems disappears at low enough energies and temperatures.Comment: 4 pages, 3 figure

    Climate Change and invasibility of the Antarctic benthos

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    Benthic communities living in shallow-shelf habitats in Antarctica (<100-m depth) are archaic in their structure and function. Modern predators, including fast-moving, durophagous (skeleton-crushing) bony fish, sharks, and crabs, are rare or absent; slow-moving invertebrates are the top predators; and epifaunal suspension feeders dominate many soft substratum communities. Cooling temperatures beginning in the late Eocene excluded durophagous predators, ultimately resulting in the endemic living fauna and its unique food-web structure. Although the Southern Ocean is oceanographically isolated, the barriers to biological invasion are primarily physiological rather than geographic. Cold temperatures impose limits to performance that exclude modern predators. Global warming is now removing those physiological barriers, and crabs are reinvading Antarctica. As sea temperatures continue to rise, the invasion of durophagous predators will modernize the shelf benthos and erode the indigenous character of marine life in Antarctica
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