Health implications of stream water contamination by industrial effluents in the Onitsha urban area of Southeastern Nigeria

Nigeria has abundant surface and ground water resources many of which are polluted and can be detrimental to human health when consumed. This study investigated the effects of effluents discharged by industries into streams on the health of people who depend on stream water for domestic purposes in the Onitsha urban area of eastern Nigeria. Water samples collected from eleven discharge locations underwent physico-chemical and microbiological analyses. Data on the effects of industrial effluents on health were obtained from records in the public hospitals located in Onitsha as well as through questionnaire surveys and field observations. The results of the analyses revealed that the effluents grossly degrade surface water bodies; several parameters (temperature, iron, dissolved oxygen, turbidity, biological oxygen demand, chemical oxygen demand, lead, magnesium, total heterotrophic counts, total coliform group, pH) had values which were higher than the WHO (2011) safety limits for drinking water. The contamination of investigated streams by effluents had negative impact on the health of stream users. The discussion included health effects of polluted water and the prevalence of water borne or related diseases in the area. Implications of these findings were also discussed. Management measures capable of minimizing contamination of surface water in the study area were suggested

Early onset of neurological features differentiates two outbreaks of Lassa fever in Ebonyi state, Nigeria during 2017-2018.

Lassa fever (LF) is an acute viral haemorrhagic illness with various non-specific clinical manifestations. Neurological symptoms are rare at the early stage of the disease, but may be seen in late stages, in severely ill patients.The aim of this study was to describe the epidemiological evolution, socio-demographic profiles, clinical characteristics, and outcomes of patients seen during two Lassa fever outbreaks in Ebonyi State, between December 2017 and December 2018. Routinely collected clinical data from all patients admitted to the Virology Centre of the hospital during the period were analysed retrospectively. Out of a total of 83 cases, 70(84.3%) were RT-PCR confirmed while 13 (15.7%) were probable cases. Sixty-nine (83.1%) patients were seen in outbreak 1 of whom 53.6% were urban residents, while 19%, 15%, and 10% were farmers, students and health workers respectively. There were 14 (16.8%) patients, seen in second outbreak with 92.9% rural residents. There were differences in clinical symptoms, signs and laboratory findings between the two outbreaks. The case fatality rates were 29.9% in outbreak 1 and 85.7% for outbreak 2. Neurological features and abnormal laboratory test results were associated with higher mortality rate, seen in outbreak 2. This study revealed significant differences between the two outbreaks. Of particular concern was the higher case fatality during the outbreak 2 which may be from a more virulent strain of the Lassa virus. This has important public health implications and further molecular studies are needed to better define its characteristics