Helicobacter pylori: the causative agent of peptic ulcer

This review examines Helicobacter pylori as an organism and as the causative agent of peptic ulcers. The review also examined the classification of ulcers, how the bacterium produces the ulcer, some of the virulence factors possessed by the organism, its metabolism and growth requirements. The incidence and prevalence of peptic ulcers were originally believed to have resulted from some factors such as stress, eating spicy food, long term use of nonsteroidal anti-inflammatory agents (NSAIDs), like aspirin and ibuprofen, smoking, and many alike. presently due to the development in the field of research, researchers from different geographical locations have reported a spiralshaped Gram-negative bacterium called Helicobacter pylori to be responsible for the pathogenesis of peptic ulcer. This confirmation has been supported by the strong and effective diagnostic procedures such as urea breath test, stool test, endoscopy, and blood test. Elimination of Helicobacter pylori by treatment with antibiotics in peptic ulcer patients resulted in the healing of the ulcer. Prevention of Helicobacter pylori infections is difficult because the mode of transmission is not well known. Key words: Helicobacter pylori, peptic ulcer, causative agent

Control of Meloidogyne incognita (kofoid and white) chitwood (root-knot nematode) of Lycopersicon esculentus (tomato) using cowdung and urine

Screenhouse experiments were conducted to test the efficacy of cowdung and urine separately and in combination in the control of root-knot nematode of tomato. Equal quantities of cowdung, urine and their mixture were separately made up to one litre with autoclaved soil. Two weeks old seedlings of tomato raised in autoclaved soil were transplanted into soil manure mixture and inoculated with 1,000 second stage larvae of Meloidogyne incognita race I. Treatments were completely randomized and effects assessed based on plant height, dry weight, extent of galling and the nematode multiplication factor. Results obtained showed that cowdung, urine, and their mixture produced significantly higher result than the untreated control. Similarly, the mixture of urine and cowdung, produced significantly higher results than the separate treatments. Key words: Meloidogyne incognita, Lycopersicon esculentus, cowdung, urine, tomato. African Journal of Biotechnology Vol.3(8) 2004: 379-38

Developing a methodological framework of adopting digital twin for deconstruction planning

Wastes generated from construction and demolition (C&D) activities account for a major proportion of urban solid wastes. The large amount of C&D waste gen-erated are still being largely landfilled or downcycled worldwide. Aging built as-sets without proper C&D planning is a major cause of wastes not being efficient-ly diverted for circular use. How waste sorting could be properly planned in the early stages, not only for new construction, but also deconstruction projects is critical to minimizing C&D wastes. As there is a large amount of aging assets without digital files or even no drawings, developing a digital-driven approach to effectively estimate and categorize C&D wastes would be essential for, not just early-stage deconstruction planning, but also the development of a circular econ-omy on C&D wastes. This study is first based on a thorough literature review of existing studies of applications of digital technologies to C&D waste diversion (WD). Limitations of existing studies are evaluated, such as the lack of digital twin approach for deconstruction. Then a methodological framework is estab-lished aiming to adopt digitalization for C&D WD, specifically for existing facili-ties under deconstruction planning. Based on the current work, future study would ap-ply the methodological framework with real-world case studies to vali-date and test its effectiveness with initiated prototypes. Longer-term work can ex-tend from the current framework to Internet-of-Things and Artificial Intelligence

Developing a methodological framework for adopting digitalization for deconstruction planning

Wastes generated from construction and demolition (C&D) activities account for a major proportion of urban solid wastes. The large amount of C&D waste generated are still being largely landfilled or downcycled worldwide. Aging built assets without proper C&D planning is a major cause of wastes not being efficiently diverted for circular use. How waste sorting could be properly planned in the early stages, not only for new construction, but also deconstruction projects is critical to minimizing C&D wastes. As there is a large amount of aging assets without digital files or even no drawings, developing a digital-driven approach to effectively estimate and categorize C&D wastes would be essential for, not just early-stage deconstruction planning, but also the development of a circular economy on C&D wastes. This study is first based on a thorough literature review of existing studies of applications of digital technologies to C&D waste diversion (WD). Limitations of existing studies are evaluated, such as the lack of digital twin approach for deconstruction. Then a methodological framework is established aiming to adopt digitalization for C&D WD, specifically for existing facilities under deconstruction planning. Based on the current work, future study would apply the methodological framework with real-world case studies to validate and test its effectiveness with initiated prototypes. Longer-term work can extend from the current framework to Internet-of-Things and Artificial Intelligence. REFERENCE

Effect of Variety, Seed Rate and Row Spacing on the Growth and Yield of Rice in Bauchi, Nigeria

Field experiments were conducted at Abubakar Tafawa Balewa University, Fadama Farm Bauchi, during the rainy seasons of 2006 and 2007 to study the effects of variety, seeding rate and row spacing on growth and yield of rice. Two varieties of rice; Ex – China (Indigenous and upland/lowland) and NERICA-1 (improved and upland), three seeding rates (32, 54 and 75 kg/ha) and four row spacings (15, 20, 25 and broadcast) were used during the study. The treatments were combined and laid in a split – split plot design with three replications. Variety was placed in the main plot, seeding rate in the sub plot while row spacing was placed in sub –sub plot. Data were collected on parameters such as plant height, number of tillers per plant, spikes per hill, spikelets per spike and number of seeds per spike, seed weight per hill, 1000 grain weight and yield kg ha-1 and analyzed using analysis of variance procedure for split – split plot and significant differences among the treatment means were separated using the Duncan multiple range test (DMRT). Variety Ex-China produced significantly (P<0.05) higher numbers of tillers per plant and spikes per hill. However, NERICA-1 produced significantly (P<0.05) higher numbers of spikelets per spike, seeds per spike, weight of seed per spike, weight of seed per hill, 1000 grain weight and yield in kg ha-1 than Ex-China. Row spacings of 15, 20 and 25cm also had significant effects on the number of tillers per plant, number of spikes per hill, number of spikelets per spike, number of seeds per spike, weight of seed per spike, weight of seed per hill, 1000 grain weight and yield kg ha-1 over the control. From the factors studied, seeding rate did not show any significant difference during the two years of investigation. Interactions were also observed among the factors studied. Therefore, row spacings irrespective of the method used, or hole planting of rice could be more appropriate for optimum grain yield.Key words: Seed rate, Row spacing, Spike

The impact of organisation culture on effective exploitation of building information modelling, big data analytics and internet of things (BBI) for competitive advantage in construction organisations

The purpose of this paper is to analyse the impact of organisational culture on the exploitation of three technological innovations: Building Information Modelling, Big Data Analytics and Internet of Things (BBI) considering the role of organisational culture as a determinant of organisational competitive advantage. After reviewing the literature on organisational culture and its relationship with competitiveness, this paper further analyses the critical culture constructs that impact specifically on exploitation of Building Information Modelling, Big Data Analytics and Internet of Things which leads to maximise organisational competitive advantage. Findings reveal that organisational culture can be both positively and negatively associated with aforementioned technological innovations depending on its key attributes for exploitation. Hence, culture of an organisation has the potential of fostering innovative technologies, but can also act as a barrier depending on how they are operationalised. The findings additionally show that in order to enhance innovation, neither a flexibility focus (which is rooted in collaboration and shared commonalities) nor an external focus (built upon the dynamics of competition and achieving concrete results) alone would suffice- both are equally critical in characterising organisational culture. The paper focuses on a context, where there is a lack of studies on the impact of cultural constructs that are specifically relevant to BBI, which lays the basis for the originality of this paper. Findings can guide managers’ efforts in organisational culture developments which foster exploitation of these technologies towards maximising the competitive edge

Growth performance, carcass and organ characteristics of growing rabbits fed graded levels of Moringa oleifera leaf meal in diets

An experiment was conducted at the Department of Animal Science teaching and research farm, Bayero University Kano, to evaluate the effect of feeding graded levels of Moringa oleifera leaf meal (MOLM) in diets on growth performance, carcass and organ characteristics of weaned rabbits. Twenty eight grower rabbits of averagely 975g in weight were allotted into four treatments of seven rabbits each in a completely randomize design. Four isonitrogenous diets (16% CP) were formulated in which MOLM was included at 0, 15, 30 and 45% for treatments 1, 2, 3 and 4 respectively. The diets were fed to the animals for eight weeks. The result showed that daily weight gain (5.95-13.39g/day) and carcass weight (497.70-727.65g) increased (P<0.05) with increasing levels of MOLM in diets, but dressing percentage (42.49-45.96%) was not affected by dietary treatments. Similarly, the weight of liver (40.35-57.05g), lungs (10.22-11.24g), heart (2.95-4.10g), kidney (8.30-10.70g), kidney fat (11.10-12.65g), small intestine (81.25-99.80g), large intestine (102.45-117.95g), caecum (20.50- 30.50g), stomach (90.75-114.65g), spleen (1.00-1.80g) and abdominal fat (7.89-11.25g) characteristics were not different across the treatments. The results indicate that weaned rabbits can utilize Moringa oleifera leaf meal at up to 45% level of inclusion in diets without any deleterious effects on growth performance, carcass yield and organ characteristics.Key words: Carcass yield, growth, Moringa oleifera, organ characteristics, rabbit

Effect of ethanol root extract of Gardenia sokotensis on the level of parasitaemia in Trypanosoma brucei brucei-infected rabbits

A study was conducted to determine the effect of the ethanol roots extract of Gardenia sokotensis in rabbits infected with Trypanosoma brucei brucei. The animals were divided into five groups of 6 each. Group A was infected and treated with the extract of G. sokotensis; Group B infected and treated with Berenil®; Group C infected and untreated; Group D uninfected but treated with the extract; Group E was uninfected and untreated. The experimental animals were inoculated intraperitoneally with approximately 104 - 5 x 105 Trypanosoma brucei brucei parasites. Berenil® was administered once, intramuscularly, at the dose rate of 3.5 mg/kg body weight, while the extract of G. sokotensis was administered orally at the rate of 60mg/kg body weight daily for seven days. Administration was done at peak of parasitaemia (41 days post infection, p.i.). The animals were examined daily for parasitemia

Proximate Composition, Phytochemical and Elemental Analysis of Some Organic Solvent Extract of The Wild Mushroom- Ganoderma lucidum.

Brief about the title: The crude extract powder of Ganoderma lucidum harvested from Lafia, Nassarawa State of Nigeria during the rainy season was analyzed for proximate contents, phytochemical constituents and mineral composition using various standard methods. Description of the experiment and procedures: The harvested Ganoderma lucidum was air dried at 370C and grinded to powder; this was preliminary analyzed for proximate contents, phytochemical constituents. The crude powder was subjected to soxhlet extraction at 400C using Methanol, Ethylacetate and N-butanol to obtain different organic solvent fractions, these were then concentrated in vacuo at 240C for 48 hours to obtain different solvent extract fractions. These extracts were then analyzed for phytochemical contents using standards methods. Results: Analysis for proximate constituent showed Moisture contents was 10.54%, Total ash 5.93%, Protein 17.55%, Crude Fats 2.60%, Crude Fiber 30.25%, Carbohydrates 33.13%, and Nitrogen 23.52%. Phytochemical screening from unprocessed G.lucidum powder reveals the presence of:  Alkaloids, Flavonoids, Reducing sugars, Tannins, Cardiac glycosides, Anthraquinones, Saponins, Volatile oils and Steroids. However, variations in the presence and concentrations of these phytochemicals were observed in the partitioned portions separated by Methanol, Ethyl acetate and N-butanol. Analysis of Total ash reveals in (mg/kg) the presence of Ca (322.6), K (317.1), P (197.1), and Na (193.5) in high quantity, while C (68.2), Fe (44.6), and Zn (14.65) and Mg (8.7.0), were found to be in moderate quantity. However, Si (4.10), Mn (1.83), As (1.23), Cu (0.84), Cr (0.14), Pb (0.106), Mo (0.09), Ni (0.095), F (0.0039), Al (0.20) and Co (0.026) are very low in concentration, but Se (0.00) was completely not detected. Conclusion: The presence of these essential nutrients and minerals found in G.lucidum implies that it can be utilized for its medicinal values in healthcare delivery systems, and the medicinal importance are thus highlighted in this work. Keywords: Ganoderma lucidum, Fruiting body, proximate analysis, Phytochemical and Mineral, Healthcar

Studies on Urinary Schistosomiasis in Selected Villages around Gusau Dam Site, Zamfara State, Nigeria

A study on urinary schistosomiasis was conducted to determine its prevalence and intensity in five villages around Gusau Dam, Gusau Local Government Area, Zamfara state. A total of five hundred (500) urinesamples were examined for the eggs of Schistosoma haematobium using standard filtration technique. The overall prevalence was 47%. However, the highest prevalence (65.47%) of the infection was recorded in Bokawa. The mean egg count for the whole study area was 237.94 eggs/10ml of urine. Koramar Gora had comparatively high mean egg count of 330.46 eggs/10ml, than other villages. Prevalence of the infection based on the sources of drinking water has indicated that, those persons who use river (60.00%), pond (50.37%) and dam (46.15%), respectively as their sources of water had higher prevalence than those who use well (38.05%), borehole (19.35%) and others (18.75%) who use tap and packaged water, at Gusau (capital city) during their business. However, a highly significantassociation (x2 = 36.571; df=5; P<0.01) was found between prevalence of infection and source of drinking water. This study revealed that, the study area is endemic for urinary schistosomiasis and there is therefore, the need for government intervention to effectively control the disease in the area.Keywords: Urinary, S. haematobium, Inhabitants, Gusau, Dam Sit