Neuer Blick auf Sprachaffekte und Emotionen in der linguistischen Forschung

Bartoszewicz, Iwona; Szczęk, Joanna; Tworek, Artur (Hg.): Linguistische Treffen in Wrocław, Vol. 17 (I). Wrocław: Oficyna Wydawnictwo ATUT – Wrocławskie Wydawnictwo Oświatowe, Neisse Verlag 2020, 424 S

Rozedrgane serca fanek, czyli jak pisać z pasją o fandomie Recenzja książki Fandom. Fanowskie modele odbioru Aldony Kobus

Recenzja monografii Aldony Kobus pt. Fandom. Fanowskie modele odbioru. Recenzja składa się z: omówienia dyskursu badań nad fanami, analizy metodologii zastosowanej w pracy, streszczenia poszczególnych rozdziałów oraz komentarza końcowego

Randomized controlled clinical trials versus real-life atrial fibrillation patients treated with oral anticoagulants. Do we treat the same patients?

Background: The aim of the study was to compare clinical characteristics of real-life atrial fibrillation (AF) patients with populations included in randomized clinical trials (ROCKET AF and RE-LY).Methods: The analysis included 3528 patients who are participants of the ongoing, multicentre, retrospective CRAFT study. The study is registered in ClinicalTrials.gov: NCT02987062. The study is based on a retrospective analysis of hospital records of AF patients treated with vitamin K antagonists (VKAs) (acenocoumarol, warfarin) and non-vitamin K oral anticoagulants (NOACs) (dabigatran, rivaroxaban). CHADS2 score was used for risk of stroke stratification.Results: VKA was prescribed in 1973 (56.0%), while NOAC in 1549 (44.0%), including dabigatran — 504 (14.3%) and rivaroxaban — 1051 (29.8%), of the 3528 patients. VKA patients in the CRAFT study were at significantly lower risk of stroke (CHADS2 1.9 ± 1.3), compared with the VKA population from the RE-LY (2.1 ± 1.1) and the ROCKET-AF (3.5 ± 1.0). Patients in the CRAFT study treated with NOAC (CHADS2 for patients on dabigatran 150 mg — 1.3 ± 1.2 and on rivaroxaban — 2.2 ± 1.4) had lower risk than patients from the RE-LY (2.2 ± 1.2) and the ROCKET AF (3.5 ± 0.9).Conclusions: Real-world patients had a lower risk of stroke than patients included in the RE-LY and ROCKET AF trials

Echocardiographic assessment of tricuspid regurgitation and pericardial effusion after cardiac device implantation

Background: The frequency of cardiac implantable electronic device (CIED) implantations is constantly increasing. Pericardial effusion (PE) and tricuspid regurgitation (TR) may occur after CIED implantation. The aim of the present study is to evaluate the prevalence and risk factors for new occurrences or progression of TR and PE early after CIED implantation. Methods: This is an on-going, single-center, observational study of patients after their first CIED implantation, with an echocardiographic evaluation within 60 days before and 7 days after the procedure. Data are presented for first 110 consecutive patients who underwent CIED implantation from August 2015 to July 2016. Results: Median age was 75 years, and 44% were women. In total, 87 (79%) pacemakers, 21 (19%) implantable cardioverter-defibrillators and 2 cardiac resynchronization therapy devices were implanted. After CIED implantation, there was TR progression in 17 (16%) patients: 5 patients developed moderate TR, none developed severe TR. An increase in TR was more often observed after implantations performed by operators in training than by certified operators (35% vs. 12%, p = 0.02). New PE after the procedure was observed in 8 (7%) patients and was trivial ( < 5 mm) in all cases. Patients with new PE after implantation had lower baseline hemoglobin levels and tended to be women. Conclusions: New PE and an increase in TR severity are rare complications early after CIED implantation. Operator experience might be related to TR progression. Increasing the number of patients in the current on-going study will allow a more reliable assessment of the prevalence and risk factors of these complications

Study design and rationale for biomedical shirt-based electrocardiography monitoring in relevant clinical situations: ECG-shirt study

  Background: Today, the main challenge for researchers is to develop new technologies which may help to improve the diagnoses of cardiovascular disease (CVD), thereby reducing healthcare costs and improving the quality of life for patients. This study aims to show the utility of biomedical shirt-based electrocardiography (ECG) monitoring of patients with CVD in different clinical situations using the Nuubo® ECG (nECG) system. Methods: An investigator-initiated, multicenter, prospective observational study was carried out in a cardiology (adult and pediatric) and cardiac rehabilitation wards. ECG monitoring was used with the biomedical shirt in the following four independent groups of patients: 1) 30 patients after pulmonary vein isolation (PVI), 2) 30 cardiac resynchronization therapy (CRT) recipients, 3) 120 patients during cardiac rehabilitation after myocardial infarction, and 4) 40 pediatric patients with supraventricular tachycardia (SVT) before electrophysiology study. Approval for all study groups was obtained from the institutional review board. The biomedical shirt captures the electrocardiographic signal via textile electrodes integrated into a garment. The software allows the visualization and analysis of data such as ECG, heart rate, arrhythmia detecting algorithm and relative position of the body is captured by an electronic device. Discussion: The major advantages of the nECG system are continuous ECG monitoring during daily activities, high quality of ECG recordings, as well as assurance of a proper adherence due to adequate comfort while wearing the shirt. There are only a few studies that have examined wearable systems, especially in pediatric populations. Trial registration: This study is registered in ClinicalTrials.gov: Identifier NCT03068169. (Cardiol J 2018; 25, 1: 52–59

Out-of-hospital cardiac arrest: Do we have to perform coronary angiography?

Out-of-hospital cardiac arrest (OHCA) remains a leading cause of global mortality, while survivors are burdened with long-term neurological and cardiovascular complications. OHCA management at the hospital level remains challenging, due to heterogeneity of OHCA presentation, the critical status of OHCA patients reaching the return of spontaneous circulation (ROSC), and the demands of post ROSC treatment. The validity and optimal timing for coronary angiography is one important, yet not fully defined, component of OHCA management. Guidelines state clear recommendations for coronary angiography in OHCA patients with shockable rhythms, cardiogenic shock, or in patients with ST-segment elevation observed in electrocardiography after ROSC. However, there is no established consensus on the angiographic management in other clinical settings. While coronary angiography may accelerate the diagnostic and therapeutic process (provided OHCA was a consequence of coronary artery disease), it might come at the cost of impaired post-resuscitation care quality due to postponing of intensive care management. The aim of the current statement paper is to discuss clinical strategies for the management of OHCA including the stratification to invasive procedures and the rationale behind the risk-benefit ratio of coronary angiography, especially with patients in critical condition

Lekarze w Chińskiej Republice Ludowej - przegląd regulacji dostyczących praktykowania medycyny

Medycyna w Chinach ma bardzo długą historię, sięgającą czasów starożytnych. Współcześnie w Chińskiej Republice Ludowej można zaobserwować tendencję do powrotu i promocji medycyny tradycyjnej na równi z medycyną konwencjonalną do tego stopnia, że została ona uregulowana w odrębnej ustawie. Co istotne, osoby zajmujące się medycyną tradycyjną mogą, po zdaniu odpowiednich egzaminów i spełnieniu określonych warunków, zdobyć uprawnienia lekarskie na równi z absolwentami studiów medycznych. W artykule na podstawie wybranych ustaw przedstawiono niezwykle złożony i różnorodny system praw i obowiązków, którym podlegają lekarze i urzędnicy zajmujący się ochroną zdrowia publicznego.The People’s Republic of China is a very big and diverse country with huge urban and rural populations. Providing such a number of people with even a basic healthcare coverage is challenging at the best of circumstances. This, combined with several thousand years of traditional medical practices, and a radical transformation the  country has been undergoing for the last forty years creates a varied regulatory landscape. In this article, the author presents selected regulations concerning Chinese medical practitioners and a brief history of medicine in China. It begins by presenting the historical background of medicine in China – from the ancient to modern  times. The historical part is followed by an overview of selected contemporary regulations on medical practitioners in the People’s Republic of China such as practitioners’ licensing, the role of Traditional Chinese Medicine, professional and tort liability of doctors. In this article, the author also presents the huge and resurgent influence of Traditional Chinese Medicine: its own separate Law, a path to full medical licence for TCM practitioners and the state placing it as a part of the larger health-care system

Calculated neutron energy dependence of the dose-response of large recombination chamber

A model of REM-2-type chamber was modeled with MCNPX code to study the dose-response to monoenergetic neutrons in wide energy range from thermal to 20 MeV for various compositions of gas in the chamber. The energy dependence of the total dose absorbed in the fi lling gas was compared with the energy dependence of ambient absorbed dose D*(10) and with experimental data. The results of the studies will be useful for designing new, improved generation of recombination chambers