Universal interactive Gaussian quantization with side information

We consider universal quantization with side information for Gaussian observations, where the side information is a noisy version of the sender's observation with an unknown noise variance. We propose a universally rate optimal and practical quantization scheme for all values of unknown noise variance. Our scheme is interactive, uses Polar lattices from prior work, and proceeds by checking in each round if a reliable estimate has been formed. In particular, our scheme is based on a structural decomposition of the underlying auxiliaries so that even when recovery fails in a round, the parties agree on a common "reference point" that is closer than the previous one.Comment: To appear in Information Theory Workshop, Italy, 2020 (to be held in April 2021

(LaCrO3)m/SrCrO3 superlattices as transparent p-type semiconductors with finite magnetization

The electronic and magnetic properties of (LaCrO3)m/SrCrO3 superlattices are investigated using first principles calculations. We show that the magnetic moments in the two CrO2 layers sandwiching the SrO layer compensate each other for even m but give rise to a finite magnetization for odd m, which is explained by charge ordering with Cr3+ and Cr4+ ions arranged in a checkerboard pattern. The Cr4+ ions induce in-gap hole states at the interface, implying that the transparent superlattices are p-type semiconductors. The availability of transparent p-type semiconductors with finite magnetization enables the fabrication of transparent magnetic diodes and transistors, for example, with a multitude of potential technological applications

AN EXHAUSTIVE STATISTIC ON CURRENT MUCOADHESIVE INTRAVAGINAL DRUG DELIVERY METHODOLOGIES

The vaginal course of medication conveyance offers many focal points because of its huge permeation range, rich vascularization, avoidance of first pass metabolism and relatively low enzymatic activity. A few examinations have demonstrated that for sedate organization the vaginal pit is a viable course which expected for the most part for neighborhood activity and conveying drugs for foundational impacts with uterine focusing on. It was first Sobrero who endeavored the vaginal mucosa for tranquilize assimilation, from that point forward much research has been done on the organization of medications through this course. As of late, for vaginal dose frame, different plan and application has expanded impressively. It is fundamentally the conveyance of medications inside or through the vaginal mucosa for neighborhood or foundational pharmacological activity. Degree of medication ingestion and its rate after organization may shift contingent upon vaginal physiology, age of the patient, arrange in the menstrual cycle, neurotic conditions and detailing factors. Here in this audit, there’s a feature, the advantages and confinements of vaginal medication conveyance, philosophy in assessment of vaginal medication conveyance frameworks, pharmaceutical viewpoints and an outline of late advances made in the bailiwick of vaginal medication conveyance. Advancement of measurements frame in various stages and in the market, are likewise audited.         Peer Review History: Received 27 November 2017;   Revised 19 December; Accepted 5 January, Available online 15 January 2018 Academic Editor: Dr. Emmanuel O. Olorunsola, Department of Pharmaceutics & Pharmaceutical Technology, University of Uyo, Nigeria, [email protected] UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file:        Reviewer's Comments: Average Peer review marks at initial stage: 4.5/10 Average Peer review marks at publication stage: 7.0/10 Reviewer(s) detail: Dr. Iman Muhammad Higazy, National Research Center, Egypt, [email protected] Dr. Robert Tungadi, State University of Gorontalo, Indonesia, [email protected] Similar Articles: THE PREVALENCE OF VULVOVAGINAL CANDIDIASIS IN PREGNANT WOMEN ATTENDING SEVERAL HOSPITALS IN SANA’A, YEME

Preparation of probiotic-loaded solid lipid nanoparticles and in vitro survival in gastrointestinal conditions

In the present study, Probiotics (Lactobacillus plantarum) loaded-solid lipid nanoparticles were prepared and characterized. Probiotics have proven to possess significant potential in addressing a range of conditions, encompassing neurodegenerative disorders, cancers, cardiovascular diseases, and inflammatory conditions. Additionally, they show efficacy in sustaining a harmonious gut microbiota ecosystem. SLNs were prepared by using solvent emulsification-diffusion technique. The size and morphology of prepared probiotic-loaded SLNs were examined by transmission electron microscopy. The activity or viability of probiotics might be compromised in the challenging gastric conditions of the stomach or in the presence of bile salts. Furthermore, they may face vulnerability to thermal or oxidative stress during preparation and storage. Hence, there is a need for stable probiotic formulations to surmount diverse physicochemical, biopharmaceutical, and biological barriers, ensuring maximal therapeutic effectiveness and clinical applicability. In vitro experiments were carried out with the aim of examining the viability of bacterial cells under gastrointestinal conditions. Encapsulation of the cells protect the cell numbers (colony forming unit) when compared to free bacteria. Nevertheless, the number of probiotic cells decreased in gastrointestinal acidic condition in contrast to free cells. Overall encapsulation of Lactobacillus plantarum in SLN’s plays an important role in enhancing viability and stability which consequently enhance the survival of bacteria against gastrointestinal environmental conditions

Assessment of dimensional stability, biodegradability, and fracture energy of bio composites reinforced with novel pine cone

In this investigation, biodegradable composites were fabricated with polycaprolactone (PCL) matrix reinforced with pine cone powder (15%, 30%, and 45% by weight) and compatibilized with graphite powder (0%, 5%, 10%, and 15% by weight) in polycaprolactone matrix by compression molding technique. The samples were prepared as per ASTM standard and tested for dimensional stability, biodegradability, and fracture energy with scanning electron micrographs. Water-absorption and thickness-swelling were performed to examine the dimensional stability and tests were performed at 23 °C and 50% humidity. Results revealed that the composites with 15 wt % of pine cone powder (PCP) have shown higher dimensional stability as compared to other composites. Bio-composites containing 15–45 wt % of PCP with low graphite content have shown higher disintegration rate than neat PCL. Fracture energy for crack initiation in bio-composites was increased by 68% with 30% PCP. Scanning electron microscopy (SEM) of the composites have shown evenly-distributed PCP particles throughout PCL-matrix at significantly high-degrees or quantities of reinforcing

Design of ohmic contacts between Janus MoSSe and two-dimensional metals

Abstract Two-dimensional semiconductors are considered as channel materials for field-effect transistors to overcome short-channel effects and reduce the device size. As the contacts to the metallic electrodes are decisive for the device performance, we study the electronic properties of contacts between Janus MoSSe and various two-dimensional metals. We demonstrate that weak interactions at these van der Waals contacts suppress Fermi level pinning and show that ohmic contacts can be formed for both terminations of Janus MoSSe, generating favorable transport characteristics

Study of inter-relationship of depression, seizure frequency and quality of life of people with epilepsy in India

Epilepsy is a chronic neurological disorder that can have profound physical, social and psychological consequences. We aimed to assess the clinical predictors of quality of life of people with epilepsy. We recruited 31 patients suffering from epilepsy in this cross-sectional study. Their clinical profile was recorded. Quality Of Life in Epilepsy (QOLIE-31) was used to assess quality of life of our patients. Depression was screened by Neurological Disorders Depression Inventory in Epilepsy (NDDI-E). Among all the clinical variables, only seizure frequency significantly correlated with seizure worry (P=0.002), emotional well-being (P=0.026) and social functions (P=0.013) subscales of QOLIE-31. NDDI-E score showed a significant negative correlation with all the subscales of QOLIE-31 except medication effects (P=0.993). A significant positive correlation was also noted between seizure frequency and NDDI-E score (r=0.417, P=0.020). Seizure frequency and depression are the most important predictors of quality of life in epilepsy patients. The management of patients with epilepsy should not only be aimed at just preventing seizures but the treating clinicians should also be cognizant about depression which itself can significantly affect the quality of life of patients

Role of Intra-abdominal Pressure in Early Acute Kidney Injury: A Prospective Cohort Study in Critically Ill Obstetric Patients

This prospective cohort study evaluated intra-abdominal pressure (IAP) and its role in causing acute kidney injury (AKI) in critically ill obstetric patients and utility of urinary neutrophil gelatinase-associated lipocalin (NGAL) to predict AKI. A total of 50 eligible obstetric patients admitted to our Intensive Care Unit were enrolled and daily IAP measured using indwelling Foley catheter. Early AKI was diagnosed as per the KDIGO criteria and urine assessed for NGAL using ELISA. AKI was seen in 54% and intra-abdominal hypertension (IAH) in 21% patients. In patients with and without AKI, there was statistically similar IAP on day 1 ( = 0.542) and day 2 ( = 0.907) as well as incidence of IAH (19% vs. 23%) ( = 0.766). Area under receiver operating characteristic curve (AUC) for IAP to predict early AKI was 0.499 (95% confidence interval [CI]: 0.325-0.673) ( = 0.992). Urinary NGAL concentration was significantly greater in patients with early AKI compared to those without ( = 0.006); AUC for urinary NGAL to detect early AKI was 0.734 (95% CI: 0.583-0.884) ( = 0.006) and optimal cutoff was 53.7 ng/ml. IAH and AKI are common in critically ill obstetric patients. While IAP does not correlate with early AKI, NGAL is useful to predict AKI

Retracted: Knowledge, attitude, and practice of contraception among women attending a tertiary care hospital

The article "Knowledge, attitude, and practice of contraception among women attending a tertiary care hospital" is retracted by the Editor-in-Chief, due to violation of the policies and practices of International Journal of Reproduction, Contraception, Obstetrics and Gynecology. The article is retracted due to dispute in authorship

A global prospective of medical devices and their regulations

Health of the public is one of the important factors which influence the wellbeing state of a human being. The diagnosis of any chronic disease or disorder & to develop treatment for that particular diseased condition is only possible after the involvement of medical devices & combination products which wasn’t possible in previous years. The detailed differentiation of medical devices is based majorly on the risk factor involved from low risk to that of high one. To get the better understanding regarding all the medical devices the regulations prevailing to particular device can be studied. The goal of developing medical device regulation systems is to protect public’s health while also ensuring their safety & performance. These regulations of medical devices products are governed by FDA which also monitors the safety & efficacy of all medical products. Innovation further leads to manufacture of new medical device. As the pharmaceutical sector & engineering department work hand in hand which has played a vital role in the physiology of organs, better performance, & better life span & in complete replacement of that particular organ system.&nbsp