5 research outputs found
Fractional order Fourier transform-based fringe-adjusted joint transform correlator
176-186An extended fractional Fourier transform (FRT) based fringe-adjusted joint transform correlator (JTC) for real-time target recognition applications has been implemented. In real-time situation, the input scene is captured using a charge-coupled device camera. The joint input images are fractional Fourier transformed and the joint power spectrum (JPS) has been recorded. Thus obtained JPS is multiplied by a pre-synthesized fringe-adjusted filter (FAF) to yield fractional fringe-adjusted JPS (FrFJPS). The FRT based fringe-adjusted JTC (FrFJTC) has been found to yield better results in comparison to the conventional fringe-adjusted JTC (FJTC). Three performance measure parameters; correlation peak intensity, peak-to-correlation energy and peak-to-sidelobe ratio have been calculated. Computer simulation and experimental results are presented
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Changes in structure and functions of prostate by longâterm administration of an androgen, testosterone enanthate, in rhesus monkey (Macaca mulatta)
The increasing use of androgens in clinical trials for developing a safe, effective, and reversible male contraceptive has necessitated a critical evaluation of the effects of their longâterm use on the structure and functions of the prostate gland, which is androgen dependent. Combination regimens using progestogens, gonadotropinâreleasing hormone antagonists, or antiandrogens along with androgens are undergoing clinical evaluation as antispermatogenic agents. The majority of these regimens have used testosterone enanthate (TE) as the androgen of choice, but very limited information is available on the side effects of longâterm androgen use. The present study is the first report that critically evaluates the effects of longâterm use of TE on prostate structure and functions.
Adult male rhesus monkeys received intramuscular injections of 50 mg of TE once in 14 days for 33 months. The cranial and caudal lobes of the prostate, which were removed under ketamine anesthesia, were processed for the preparation of semithin sections to evaluate histological changes. The DNA distribution in the cells was studied in single cell suspensions of cranial and caudal lobes of the prostate by using flow cytometry. Changes in the levels of testosterone, estradiol, prostateâspecific acid phosphatase (PAP), and prostateâspecific antigen (PSA) in samples collected during the pretreatment period and at the time of removal of the prostate were estimated by using conventional procedures. Control samples were processed simultaneously. The administration of TE for 33 months caused the following changes: 1) significant increase in the weight of both lobes of the prostate, 2) cellular hypertrophy and increase in secretory material in the cells and in the lumen of the acini in the central and peripheral zones of the two lobes of the prostate, 3) cellular hyperplasia indicated by flow cytometric analysis of DNA content, 4) significant increase in the secretion of PAP and levels of estradiol, and 5) a marked increase in fibromuscular stroma in the central and peripheral zones of both the lobes of the prostate.
The present study is the first report to provide evidence that longâterm androgen treatment has caused hypertrophy of the prostatic epithelial cells, which showed increased secretory activity. The hyperplastic changes indicate a need for the development of new androgens with a better pharmacokinetic profile for use in male contraceptive regimens. Anat. Rec. 252:637â645, 1998. © 1998 WileyâLiss, Inc
Retracted: Knowledge, attitude, and practice of contraception among women attending a tertiary care hospital
The article "Knowledge, attitude, and practice of contraception among women attending a tertiary care hospital" is retracted by the Editor-in-Chief, due to violation of the policies and practices of International Journal of Reproduction, Contraception, Obstetrics and Gynecology. The article is retracted due to dispute in authorship