26 research outputs found
Induction and transfer of resistance to poisoning by Amorimia pubiflora in sheep whith non-toxic dosis of the plant and ruminal content
Ultrastructural lesions in the myocardium and kidneys of rabbits in experimental acute Amorimia exotropica poisoning
Intoxicação experimental por monofluoroacetato de sódio em bovinos: aspectos clÃnicos e patológicos
Factors influencing the fecal egg and oocyst counts of parasites of wild European rabbits Oryctolagus cuniculus (L.) in southern western Australia
Abundance of intestinal parasites was monitored by fecal egg and oocyst counts for samples of wild rabbits Oryctolagus cuniculus with different levels of imposed female sterility from 12 populations in southwestern Australia. Differences in egg counts of Trichostrongylus retortaeformis between seasons and age groups were dependent on the sex of the host. Pregnancy may have been responsible for these differences because egg counts were consistently higher in intact females than in females surgically sterilized by tubal ligation. Egg counts for Passalurus ambiguus were influenced by season and host age but there were no differences between sexes or between intact and sterilized female rabbits. No differences were detected in the oocyst counts of the 8 species of Eimeria between male and female rabbits or between intact and sterilized females. Seasonal differences were detected in oocyst counts of Eimeria flavescens and Eimeria stiedai. The overwhelming determinant of coccidian oocyst counts was host age, with 6 species being much more abundant in rabbits up to 4 mo of age. There was a suggestion that egg counts of T. retortaeformis and oocyst counts of several species of Eimeria were reduced in populations where rabbit numbers had been depressed for at least 2 yr, but there was no evidence that short-term variations in rabbit numbers had a measurable effect on parasite abundance
Evaluation of the association of parasitism with mortality of wild European rabbits Oryctolagus cuniculus (L.) in southwestern Australia
Abundances of the parasitic nematodes Trichostrongylus retortaeformis and Passalurus ambiguus, and 8 Eimeria species were estimated by fecal egg and oocyst output in 12 discrete free-ranging populations of wild rabbits (Oryctolagus cuniculus) in southwestern Australia. Comparisons of parasite egg and oocyst counts were made between those rabbits known to have survived at least 2 mo after fecal samples were collected and those rabbits that did not survive. There were significant negative relationships between parasite egg and oocyst counts and survival when all age groups and collection periods were pooled for several species of coccidia and for T. retortaeformis. However, when the same comparisons were made within rabbit age groups and within collection periods, there were very few significant differences even where sample sizes were quite large. The differences indicated by the pooled analysis for coccidia were most likely due to an uneven host age distribution with respect to survival, combined with an uneven distribution of the oocyst counts with rabbit age. The result for T. retortaeformis was similarly affected but by a seasonal pattern. Parasitism by nematodes and coccidia did not appear to be an important mortality factor in these rabbit populations, at least at the range of host densities we examined. This suggests that other factors must have been responsible for the observed pattern of density- dependent regulation in these rabbits
Comparative metabolism of, and sensitivity to, fluoroacetate in geographically separated populations of tiliqua rugosa (Gray) (Scincidae)
Populations of Tiliqua rugosa which coexist with fluoroacetate-bearing vegetation were much less sensitive to fluoroacetate intoxification than were conspecifics not exposed to the toxic plants. However, the biochemical mechanisms responsible for this toxicity differential were not ascertained. Liver acetone powder preparations from both conspecifics were similar in their abilities to detoxify fluoroacetate by defluorination, and to convert fluoroacetate into fluorocitrate. The aconitate hydratase in these preparations was also similarly inhibited by (-)erythro-fluorocitrate. These findings, and other possibilities which could be responsible for the toxicity differential, are discussed
Is sodium fluoroacetate (1080) a humane poison? The influence of mode of action, physiological effects, and target specificity
1080 (sodium fluoroacetate)-baiting programmes are an important and often the only option for reducing the impact of invasive vertebrate pests on biodiversity and agricultural production in Australia and New Zealand. These programmes are generally recognised as being target specific, and environmentally and user safe Nevertheless, although 1080 has few recognised long-term side-effects, its potential to disrupt endocrine systems has been recently raised, and there is some conjecture regarding the humaneness of 1080 for certain target species. However, the assessment of the humaneness of any vertebrate pesticide must be commensurate with its mode of action, metabolism, target specificity, and operational use. This has not always occurred with 1080, particularly regarding these aspects, and its overall effects. The actual risk faced by non-target species during baiting operations is not accurately reflected simply by their sensitivity to 1080. 1080 is not endocrine-disrupting or carcinogenic, and because of the lag phase before signs of poisoning occur, the time from ingestion to death is not a reliable indicator of its humaneness. Moreover, functional receptors and neurological pathways are required to experience pain However, as 1080 impairs neurological function, mainly through effects on acetylcholine and glutamate, and as this impairment includes some pain receptors, it Is difficult to interpret the behaviour of affected animals, or to assess their ability to experience discomfort and pain. This has implications for assessing the merits of including ameliorative agents in 1080 baits aimed at further improving welfare outcomes We also suggest that the assessment of the humaneness of any vertebrate pesticide should follow the ethical pest control approach, and on this basis, believe that the use of 1080 to reduce the detrimental impacts of invasive vertebrates is ethical, particularly with respect to the expectations of the wider community