6 research outputs found
Scientometric Indicators as a Way to Classify Brands for Customer’s Information
The paper proposes a novel approach for classification of different brands that commercialize similar products, for customer information. The approach is tested on electronic shopping records found on Amazon.com, by quantifying customer behavior and comparing the results with classifications of the same brands found online through search engines. The indicators proposed for the classification are currently used scientometric measures that can be easily applied to marketing classification
Network analytics for drug repurposing in COVID-19
To better understand the potential of drug repurposing in COVID-19, we analyzed control strategies over essential host factors for SARS-CoV-2 infection. We constructed comprehensive directed protein–protein interaction (PPI) networks integrating the top-ranked host factors, the drug target proteins and directed PPI data. We analyzed the networks to identify drug targets and combinations thereof that offer efficient control over the host factors. We validated our findings against clinical studies data and bioinformatics studies. Our method offers a new insight into the molecular details of the disease and into potentially new therapy targets for it. Our approach for drug repurposing is significant beyond COVID-19 and may be applied also to other diseases.</p
DNA origami design and implementation
Since its introduction in the early 2000s, DNA origami had a big impact on the development of nanotechnology by gathering numerous applications. During this time, many tools were designed and used to generate arbitrary shapes capable of self-assembly which make this technique more approachable. In this paper, we have created the map of Romania at nanoscale dimensions by using a new open-source software - PERDIX. For this purpose, we used a scaffold strand with a length of 6959 nucleotides and 162 staple strands with a variable length ranging between 20 and 63 nucleotides. All the computational tools that were used in this experiment are open-source and user-friendly.Peer reviewe