Cities as emergent models: the morphological logic of Manhattan and Barcelona

This paper is set to unveil several particulars about the logic embedded in the diachronic model of city growth and the rules which govern the emergence of urban spaces. The paper outlines an attempt to detect and define the generative rules of a growing urban structure by means of evaluation techniques. The initial approach in this regards will be to study the evolution of existing urban regions or cities which in our case are Manhattan and Barcelona and investigate the rules and causes of their emergence and growth. The paper will concentrate on the spatial aspect of the generative rules and investigate their behaviour and dimensionality. Several Space Syntax evaluation methods will be implemented to capture the change of spatial configurations within the growing urban structures. In addition, certain spatial elements will be isolated and tested aiming to illustrate their influence on the main spatial structures. Both urban regions were found to be emergent products of a bottom up organic growth mostly distinguished in the vicinities of the first settlements. Despite the imposition of a uniform grid on both cities in later stages of their development these cities managed to deform the regularity in the preplanned grid in an emergent manner to end up with an efficient model embodied in their current spatial arrangement. The paper reveals several consistencies in the spatial morphology of both urban regions and provides explanation of these regularities in an approach to extract the underlying rules which contributed to the growth optimization process

Cosmological baryon and lepton number in the presence of electroweak fermion-number violation

In the presence of rapid fermion-number violation due to nonperturbative electroweak effects certain relations between the baryon number of the Universe and the lepton numbers of the Universe are predicted. In some cases the electron-neutrino asymmetry is exactly specified in terms of the baryon asymmetry. Without introducing new particles, beyond the usual quarks and leptons, it is necessary that the Universe possess a nonzero value of B - L prior to the epoch of fermion-number violation if baryon and lepton asymmetries are to survive. Contrary to intuition, even though electroweak processes violate B + L, a nonzero value of B + L persists after the epoch of rapid fermion-number violation. If the standard model is extended to include lepton-number violation, for example through Majorana neutrino masses, then electroweak processes will reduce the baryon number to zero even in the presence of an initial B - L unless 20 M(sub L) approximately greater than the square root of (T(sub B - L) m(sub P1)) where M(sub L) sets the scale of lepton number violation and T(sub B - L) is the temperature at which a B - L asymmetry is produced. In many models this implies that neutrinos must be so light that they cannot contribute appreciably to the mass density of the Universe

The PL calibration for Milky Way Cepheids and its implications for the distance scale

The rationale behind recent calibrations of the Cepheid PL relation using the Wesenheit formulation is reviewed and reanalyzed, and it is shown that recent conclusions regarding a possible change in slope of the PL relation for short-period and long-period Cepheids are tied to a pathological distribution of HST calibrators within the instability strip. A recalibration of the period-luminosity relation is obtained using Galactic Cepheids in open clusters and groups, the resulting relationship, described by log L/L_sun = 2.415(+-0.035) + 1.148(+-0.044)log P, exhibiting only the moderate scatter expected from color spread within the instability strip. The relationship is confirmed by Cepheids with HST parallaxes, although without the need for Lutz-Kelker corrections, and in general by Cepheids with revised Hipparcos parallaxes, albeit with concerns about the cited precisions of the latter. A Wesenheit formulation of Wv = -2.259(+-0.083) - 4.185(+-0.103)log P for Galactic Cepheids is tested successfully using Cepheids in the inner regions of the galaxy NGC 4258, confirming the independent geometrical distance established for the galaxy from OH masers. Differences between the extinction properties of interstellar and extragalactic dust may yet play an important role in the further calibration of the Cepheid PL relation and its application to the extragalactic distance scale.Comment: Accepted for Publication (Astrophysics & Space Science

The Two-Screen Measurement Setup to Indirectly Measure Proton Beam Self-Modulation in AWAKE

The goal of the first phase of the AWAKE \cite{AWAKE1,AWAKE2} experiment at CERN is to measure the self-modulation \cite{SMI} of the $\sigma_z = 12\,\rm{cm}$ long SPS proton bunch into microbunches after traversing $10\,\rm{m}$ of plasma with a plasma density of $n_{pe}=7\times10^{14}\,\rm{electrons/cm}^3$. The two screen measurement setup \cite{Turner2016} is a proton beam diagnostic that can indirectly prove the successful development of the self-modulation of the proton beam by imaging protons that got defocused by the transverse plasma wakefields after passing through the plasma, at two locations downstream the end of the plasma. This article describes the design and realization of the two screen measurement setup integrated in the AWAKE experiment. We discuss the performance and background response of the system based on measurements performed with an unmodulated Gaussian SPS proton bunch during the AWAKE beam commissioning in September and October 2016. We show that the system is fully commissioned and adapted to eventually image the full profile of a self-modulated SPS proton bunch in a single shot measurement during the first phase of the AWAKE experiment.Comment: 5 pages 8 figure

Parameterization of Dark-Energy Properties: a Principal-Component Approach

Considerable work has been devoted to the question of how to best parameterize the properties of dark energy, in particular its equation of state w. We argue that, in the absence of a compelling model for dark energy, the parameterizations of functions about which we have no prior knowledge, such as w(z), should be determined by the data rather than by our ingrained beliefs or familiar series expansions. We find the complete basis of orthonormal eigenfunctions in which the principal components (weights of w(z)) that are determined most accurately are separated from those determined most poorly. Furthermore, we show that keeping a few of the best-measured modes can be an effective way of obtaining information about w(z).Comment: Unfeasibility of a truly model-independent reconstruction of w at z>1 illustrated. f(z) left out, and w(z) discussed in more detail. Matches the PRL versio

Human infectivity trait in <i>Trypanosoma brucei</i>: stability, heritability and relationship to sra expression

Some Trypanosoma brucei lines infect humans whereas others do not because the parasites are lysed by human serum. We have developed a robust, quantitative in vitro assay based on differential uptake of fluorescent dyes by live and dead trypanosomes to quantify the extent and kinetics of killing by human serum. This method has been used to discriminate between 3 classes of human serum resistance; sensitive, resistant and intermediate. TREU 927/4, the parasite used for the T. brucei genome project, is intermediate. The phenotype is expressed in both bloodstream and metacyclic forms, is stably expressed during chromic infections and on cyclical transmission through tsetse flies. Trypanosomes of intermediate phenotype are distinguished from sensitive populations of cells by the slower rate of lysis and by the potential to become fully resistant to killing by human serum as a result of selection or long-term serial passaging in mice, and to pass on full resistance phenotype to its progeny in a genetic cross. The sra gene has been shown previously to determine human serum resistance in T. brucei but screening for the presence and expression of this gene indicated that it is not responsible for the human serum resistance phenotype in the trypanosome lines that we have examined, indicating that an alternative mechanism for HSR exists in these stocks. Examination of the inheritance of the phenotype in F1 hybrids for both bloodstream and metacyclic stages from 2 genetic crosses demonstrated that the phenotype is co-inherited in both life-cycle stages in a manner consistent with being a Mendelian trait, determined by only one or a few genes

Non-equilibrium raft-like membrane domains under continuous recycling

We present a model for the kinetics of spontaneous membrane domain (raft) assembly that includes the effect of membrane recycling ubiquitous in living cells. We show that the domains have a broad power-law distribution with an average radius that scales with the 1/4 power of the domain lifetime when the line tension at the domain edges is large. For biologically reasonable recycling and diffusion rates the average domain radius is in the tens of nm range, consistent with observations. This represents one possible link between signaling (involving rafts) and traffic (recycling) in cells. Finally, we present evidence that suggests that the average raft size may be the same for all scale-free recycling schemes.Comment: 8 pages, 5 figure