A Method to Determine the Maximum Radius of Defocused Protons after Self-Modulation in AWAKE

The AWAKE experiment at CERN aims to drive GV/m plasma wakefields with a self-modulated proton drive bunch, and to use them for electron acceleration. During the self-modulation process, protons are defocused by the transverse plasma wakefields and form a halo around the focused bunch core. The two-screen setup integrated in AWAKE measures the transverse, time-integrated proton bunch distribution downstream the \unit[10]{m} long plasma to detect defocused protons. By measuring the maximum radius of the defocused protons we attempt calculate properties of the self-modulation. In this article, we develop a routine to identify the maximum radius of the defocused protons, based on a standard contour method. We compare the maximum radius obtained from the contour to the logarithmic lineouts of the image to show that the determined radius identifies the edge of the distribution.Comment: 3 pages, 4 figures, EAAC 2017 NIMA proceeding

Rising Expectations in Business Education

The article comments on the rising expectations in business education. It explains the term liberal education. It mentions the Liberal Education & America\u27s Promise Campaign launched by the Association of American Colleges & Universities in 2005. The article also notes that integrative learning is particularly relevant because it melds students\u27 professional and liberal educations

Proton Beam Defocusing as a Result of Self-Modulation in Plasma

The AWAKE experiment will use a \SI{400}{GeV/c} proton beam with a longitudinal bunch length of $\sigma_z = 12\,\rm{cm}$ to create and sustain GV/m plasma wakefields over 10 meters . A 12 cm long bunch can only drive strong wakefields in a plasma with $n_{pe} = 7 \times 10^{14}\,\rm{electrons/cm}^3$ after the self-modulation instability (SMI) developed and microbunches formed, spaced at the plasma wavelength. The fields present during SMI focus and defocus the protons in the transverse plane \cite{SMI}. We show that by inserting two imaging screens downstream the plasma, we can measure the maximum defocusing angle of the defocused protons for plasma densities above $n_{pe} = 5 \times 10^{14}\,\rm{electrons/cm}^{-3}$. Measuring maximum defocusing angles around 1 mrad indirectly proves that SMI developed successfully and that GV/m plasma wakefields were created. In this paper we present numerical studies on how and when the wakefields defocus protons in plasma, the expected measurement results of the two screen diagnostics and the physics we can deduce from it.Comment: 3 pages, 2 figures, Conference Proceedings of NAPAC 201

The Two-Screen Measurement Setup to Indirectly Measure Proton Beam Self-Modulation in AWAKE

The goal of the first phase of the AWAKE \cite{AWAKE1,AWAKE2} experiment at CERN is to measure the self-modulation \cite{SMI} of the $\sigma_z = 12\,\rm{cm}$ long SPS proton bunch into microbunches after traversing $10\,\rm{m}$ of plasma with a plasma density of $n_{pe}=7\times10^{14}\,\rm{electrons/cm}^3$. The two screen measurement setup \cite{Turner2016} is a proton beam diagnostic that can indirectly prove the successful development of the self-modulation of the proton beam by imaging protons that got defocused by the transverse plasma wakefields after passing through the plasma, at two locations downstream the end of the plasma. This article describes the design and realization of the two screen measurement setup integrated in the AWAKE experiment. We discuss the performance and background response of the system based on measurements performed with an unmodulated Gaussian SPS proton bunch during the AWAKE beam commissioning in September and October 2016. We show that the system is fully commissioned and adapted to eventually image the full profile of a self-modulated SPS proton bunch in a single shot measurement during the first phase of the AWAKE experiment.Comment: 5 pages 8 figure

External Electron Injection for the AWAKE Experiment

We summarize and explain the realization of witness particle injection into wakefields for the AWAKE experiment. In AWAKE, the plasma wakefields are driven by a self-modulating relativistic proton bunch. To demonstrate that these wakefields can accelerate charged particles, we inject a \unit[10-20]{MeV} electron bunch produced by a photo-injector. We summarize the experimental challenges of this injection process and present our plans for the near future.Comment: 4 pages, 3 figure

Compact ring-based X-ray source with on-orbit and on-energy laser-plasma injection

We report here the results of a one week long investigation into the conceptual design of an X-ray source based on a compact ring with on-orbit and on-energy laser-plasma accelerator. We performed these studies during the June 2016 USPAS class "Physics of Accelerators, Lasers, and Plasma..." applying the art of inventiveness TRIZ. We describe three versions of the light source with the constraints of the electron beam with energy $1\,\rm{GeV}$ or $3\,\rm{GeV}$ and a magnetic lattice design being normal conducting (only for the $1\,\rm{GeV}$ beam) or superconducting (for either beam). The electron beam recirculates in the ring, to increase the effective photon flux. We describe the design choices, present relevant parameters, and describe insights into such machines.Comment: 4 pages, 1 figure, Conference Proceedings of NAPAC 201

Universal school meals and associations with student participation, attendance, academic performance, diet quality, food security, and Body Mass Index: A systematic review

The school environment plays an important role in children\u27s diets and overall health, and policies for universal free school meals have the potential to contribute to positive child health outcomes. This systematic review evaluates studies examining the association between universal free school meals and students\u27 school meal participation rates, diets, attendance, academic performance, and Body Mass Index (BMI), as well as school finances. The search was conducted in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA). A search for studies published in economically developed countries published through December 2020 was performed in PubMed, Education Resources Information Center (ERIC), Thomson Reuters\u27 Web of Science, and Academic Search Ultimate, followed by examining the references in the resultant literature. A total of 47 studies were identified and the Newcastle-Ottawa Scale (NOS) was applied to assess bias. Nearly all studies examining universal free school meals found positive associations with school meal participation. Most studies examining universal free school meals that included free lunch found positive associations with diet quality, food security, and academic performance; however, the findings of studies examining only universal free breakfast were mixed. Research findings were similarly mixed when examining attendance as an outcome. Concerns about adverse outcomes on student BMI were not supported by the literature; in fact, several studies detected a potentially protective effect of universal free school meals on BMI. Research examining the impact of universal free meals on school finances was limited, but suggest that lower-income school districts in the U.S. may have positive financial outcomes from participation in universal free school meal provisions. Additionally, providing free meals to students may be associated with improved household incomes, particularly among lower-income families with children. Further research is needed to examine the financial implications of universal free meals for both school districts and families. Overall, universal free school meals may have multiple benefits for students and countries should consider universal free school meal provisions with strong nutrition guidelines. (PROSPERO registration: CRD42020221782)

Predicting the Trajectory of a Relativistic Electron Beam for External Injection in Plasma Wakefields

We use beam position measurements over the first part of the AWAKE electron beamline, together with beamline modeling, to deduce the beam average momentum and to predict the beam position in the second part of the beamline. Results show that using only the first five beam position monitors leads to much larger differences between predicted and measured positions at the last two monitors than when using the first eight beam position monitors. These last two positions can in principle be used with ballistic calculations to predict the parameters of closest approach of the electron bunch with the proton beam. In external injection experiments of the electron bunch into plasma wakefields driven by the proton bunch, only the first five beam position monitors measurements remain un-affected by the presence of the much higher charge proton bunch. Results with eight beam position monitors show the prediction method works in principle to determine electron and proton beams closest approach within the wakefields width ($<$1\,mm), corresponding to injection of electrons into the wakefields. Using five beam position monitors is not sufficient.Comment: seven pages, five figures, submitted for EAAC 2019 Proceeding

Deletion of airway cilia results in noninflammatory bronchiectasis and hyperreactive airways

The mechanisms for the development of bronchiectasis and airway hyperreactivity have not been fully elucidated. Although genetic, acquired diseases and environmental influences may play a role, it is also possible that motile cilia can influence this disease process. We hypothesized that deletion of a key intraflagellar transport molecule, IFT88, in mature mice causes loss of cilia, resulting in airway remodeling. Airway cilia were deleted by knockout of IFT88, and airway remodeling and pulmonary function were evaluated. In IFT88− mice there was a substantial loss of airway cilia on respiratory epithelium. Three months after the deletion of cilia, there was clear evidence for bronchial remodeling that was not associated with inflammation or apparent defects in mucus clearance. There was evidence for airway epithelial cell hypertrophy and hyperplasia. IFT88− mice exhibited increased airway reactivity to a methacholine challenge and decreased ciliary beat frequency in the few remaining cells that possessed cilia. With deletion of respiratory cilia there was a marked increase in the number of club cells as seen by scanning electron microscopy. We suggest that airway remodeling may be exacerbated by the presence of club cells, since these cells are involved in airway repair. Club cells may be prevented from differentiating into respiratory epithelial cells because of a lack of IFT88 protein that is necessary to form a single nonmotile cilium. This monocilium is a prerequisite for these progenitor cells to transition into respiratory epithelial cells. In conclusion, motile cilia may play an important role in controlling airway structure and function