467 research outputs found

    Using Machine Learning for Handover Optimization in Vehicular Fog Computing

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    Smart mobility management would be an important prerequisite for future fog computing systems. In this research, we propose a learning-based handover optimization for the Internet of Vehicles that would assist the smooth transition of device connections and offloaded tasks between fog nodes. To accomplish this, we make use of machine learning algorithms to learn from vehicle interactions with fog nodes. Our approach uses a three-layer feed-forward neural network to predict the correct fog node at a given location and time with 99.2 % accuracy on a test set. We also implement a dual stacked recurrent neural network (RNN) with long short-term memory (LSTM) cells capable of learning the latency, or cost, associated with these service requests. We create a simulation in JAMScript using a dataset of real-world vehicle movements to create a dataset to train these networks. We further propose the use of this predictive system in a smarter request routing mechanism to minimize the service interruption during handovers between fog nodes and to anticipate areas of low coverage through a series of experiments and test the models' performance on a test set

    Toward a Framework of E-Business Strategy: A Case Study Approach

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    E-business is erasing the typical boundaries of space, time, organization and community with shared interest and cooperation. The two most critical features of e-business practices are: (1) the unique capacity for customization, and (2) the trust-based sharing of information along supply chains. E-business strategy should be particularly effective for globalization. The case of Haier from China suggests that legacy firms need to develop e-business strategy to compete in the Internet Age. However, e-business must be built on a solid basis of sound business practices. The case of Haier also suggests that companies need to be creative when formulating e-business strategies for operations in the developing countries where infrastructure is underdeveloped. Further, strategic alliances between local and multinational firms are imperative for e-business in the developing countries such as China

    High optical transmittance of aluminum ultrathin film with hexagonal nanohole arrays as transparent electrode

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    We fabricate samples of aluminum ultrathin films with hexagonal nanohole arrays and characterize the transmission performance. High optical transmittance larger than 60% over a broad wavelength range from 430 nm to 750 nm is attained experimentally. The Fano-type resonance of the excited surface plasmon plaritons and the directly transmitted light attribute to both of the broadband transmission enhancement and the transmission suppression dips

    Identifying Ketamine Responses in Treatment-Resistant Depression Using a Wearable Forehead EEG

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    This study explores the responses to ketamine in patients with treatment-resistant depression (TRD) using a wearable forehead electroencephalography (EEG) device. We recruited fifty-five outpatients with TRD who were randomised into three approximately equal-sized groups (A: 0.5 mg/kg ketamine; B: 0.2 mg/kg ketamine; and C: normal saline) under double-blind conditions. The ketamine responses were measured by EEG signals and Hamilton Depression Rating Scale (HDRS) scores. At baseline, responders showed a significantly weaker EEG theta power than did non- responders (p < 0.05). Responders exhibited a higher EEG alpha power but lower EEG alpha asymmetry and theta cordance at post-treatment than at baseline (p < 0.05). Furthermore, our baseline EEG predictor classified responders and non-responders with 81.3 +- 9.5% accuracy, 82.1 +- 8.6% sensitivity and 91.9 +- 7.4% specificity. In conclusion, the rapid antidepressant effects of mixed doses of ketamine are associated with prefrontal EEG power, asymmetry and cordance at baseline and early post-treatment changes. The prefrontal EEG patterns at baseline may account for recognising ketamine effects in advance. Our randomised, double- blind, placebo-controlled study provides information regarding clinical impacts on the potential targets underlying baseline identification and early changes from the effects of ketamine in patients with TRD.Comment: This revised article is submitting to IEEE TBM

    Heavy Fermion Screening Effects and Gauge Invariance

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    We show that the naively expected large virtual heavy fermion effects in low energy processes may be screened if the process under consideration contains external gauge bosons constrained by gauge invariance. We illustrate this by a typical example of the process γγbbˉ\gamma\gamma\to b \bar{b}. Phenomenological implications are also briefly indicated.Comment: a miss-print fixed, 7 pages, LaTex, no figure

    Granulocyte Colony-Stimulating Factor Activating HIF-1α Acts Synergistically with Erythropoietin to Promote Tissue Plasticity

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    Stroke and peripheral limb ischemia are serious clinical problems with poor prognosis and limited treatment. The cytokines erythropoietin (EPO) and granulocyte-colony stimulating factor (G-CSF) have been used to induce endogenous cell repair and angiogenesis. Here, we demonstrated that the combination therapy of EPO and G-CSF exerted synergistic effects on cell survival and functional recovery from cerebral and peripheral limbs ischemia. We observed that even under normoxic conditions, G-CSF activates hypoxia-inducible factor-1α (HIF-1α), which then binds to the EPO promoter and enhances EPO expression. Serum EPO level was significantly increased by G-CSF injection, with the exception of Tg-HIF-1α+f/+f mice. The neuroplastic mechanisms exerted by EPO combined with G-CSF included enhanced expression of the antiapoptotic protein of Bcl-2, augmented neurotrophic factors synthesis, and promoted neovascularization. Further, the combination therapy significantly increased homing and differentiation of bone marrow stem cells (BMSCs) and intrinsic neural progenitor cells (INPCs) into the ischemic area. In summary, EPO in combination with G-CSF synergistically enhanced angiogenesis and tissue plasticity in ischemic animal models, leading to greater functional recovery than either agent alone

    Whole pelvic helical tomotherapy for locally advanced cervical cancer: technical implementation of IMRT with helical tomothearapy

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    <p>Abstract</p> <p>Background</p> <p>To review the experience and to evaluate the treatment plan of using helical tomotherapy (HT) for the treatment of cervical cancer.</p> <p>Methods</p> <p>Between November 1st, 2006 and May 31, 2009, 10 cervical cancer patients histologically confirmed were enrolled. All of the patients received definitive concurrent chemoradiation (CCRT) with whole pelvic HT (WPHT) followed by brachytherapy. During WPHT, all patients were treated with cisplatin, 40 mg/m<sup>2 </sup>intravenously weekly. Toxicity of treatment was scored according to the Common Terminology Criteria for Adverse Events v3.0 (CTCAE v3.0).</p> <p>Results</p> <p>The mean survival was 25 months (range, 3 to 27 months). The actuarial overall survival, disease-free survival, locoregional control and distant metastasis-free rates at 2 years were 67%, 77%, 90% and 88%, respectively. The average of uniformity index and conformal index was 1.06 and 1.19, respectively. One grade 3 of acute toxicity for diarrhea, thrombocytopenia and three grade 3 leucopenia were noted during CCRT. Only one grade 3 of subacute toxicity for thrombocytopenia was noted. There were no grade 3 or 4 subacute toxicities of anemia, leucopenia, genitourinary or gastrointestinal effects. Compared with conventional whole pelvic radiation therapy (WPRT), WPHT decreases the mean dose to rectum, bladder and intestines successfully.</p> <p>Conclusion</p> <p>HT provides feasible clinical outcomes in locally advanced cervical cancer patients. Long-term follow-up and enroll more locally advanced cervical carcinoma patients by limiting bone marrow radiation dose with WPHT technique is warranted.</p
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