A case of vertical transmission of hepatitis A virus infection

We present a case of hepatitis A infection in a 2.5-month-old male who became icteric after 18 d of birth. The diagnosis of hepatitis A was made by compatible clinical symptoms, laboratory results and liver biopsy showing evidence of hepatitis, and confirmed by detection of anti-HAV IgM antibodies. Because the mother had an acute icteric hepatitis A 1 week before delivery, and the viraemic phase of hepatitis A infection is very short, approximately 7 d, we suggest that the infant was infected by his mother, before birth

Human leukocyte antigens in Turkish pediatric celiac patients

With the aim to determine the frequency of human leukocyte antigen phenotypes of celiac disease in Turkey, thirty celiac patients fulfilling the European Society of Pediatric Gastroenterology and Nutrition criteria were included in the study. The mean age of the study population was 5.8 +/- 4.3 years and of the control subjects was 32.6 +/- 6.7 years

Wilson disease manifested primarily as amenorrhea and accompanying thrombocytopenia

Wilson disease (WD), referred to as hepatolenticular degeneration and occurring primarily as neurological and liver disease, is an inherited disorder that has various clinical presentations [1-3]. The altered gene is localized on the long arm of chromosome 13. Mutations in the Wilson gene are common and include small insertions or deletions. In the cases of unidentified tubular dysfunctions, hemolytic anemias, and urolithiasis, this disease should be kept in mind as the possible etiology. Amenorrhea has been reported in untreated women with WD [1,2,4-8]. Although thrombocytopenia, as a result of hypersplenism and/or as a side effect of D-penicillamin therapy, has been well-documented, the association of idiopathic thrombocytopenia and WD has been published in only one case previously [9]

Hennekam syndrome

Hennekam syndrome is a disorder comprising intestinal lymphangiectasia, facial anomalies and moderate mental retardation. Eight cases have been previously reporte

Management of portal hypertension in children : a retrospective study with longterm follow-up

Objectives : Data regarding the management of the portal hypertensive haemorrhage in the paediatric patients have yielded conflicting results. The purpose of this study was to evaluate the efficacy of P-blocker (propranolol) alone, sclerotherapy alone and beta-blocker + sclerotherapy combination in the management of portal hypertension in the paediatric population