The Use of Knowledge Management Methodologies to Improve the Practice of Supply Chain Management: The Case of the Bullwhip Effect

Supply Chain Management is a critically important approach toward producing and delivering goods and services in a cost-effective, timely manner. However, many SCM systems in practice exhibit the bullwhip effect, a tendency towards increasing variability in demand as this type of information migrates downwards in the producing supply chain. We argue that one can reduce the size of the bullwhip effect through the judicious use of knowledge management technologies. We have advanced our arguments through several propositions, and we have derived a set of testable hypotheses from two of these propositions in order to demonstrate how one would go about verifying these arguments. We have identified two different general research methodologies in order to provide a multiple methodological approach to gaining greater confidence in the propositions. It now remains to carry out this plan of research

Our Ministers and Song Leaders of the Church of Christ

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Mapping of the Melatonin Receptor 1a (MTNR1A) Gene in Pigs, Sheep and Cattle

Human and sheep Melatonin receptor 1a (MTNR1A) gene information was used to clone a portion of the coding region of this gene in pigs, and to identify polymorphisms of the gene for its assignment to both the genetic linkage and physical maps. MTNR1A maps to pig chromosome 17, establishing a new region of conserved synteny between this chromosome and human chromosome 4. Furthermore, we have assigned MTNR1A to bovine chromosome 27 and sheep chromosome 26. The addition of genes like MTNR1A to livestock genome maps allows questions about evolutionary events and the genetic basis for quantitative traits in livestock to be addressed

Quantitative Measurement of PIT1, GH, and PRL mRNA and Circulating Hormone Levels in Pig Families Segregating PIT1 Genotypes

PIT1 is a member of the POU-domain family gene and is a positive regulator for growth hormone (GH), prolactin (PRL), and thyrotroph-stimulating hormone β(TSHB) in several mammalian species. Previous studies in pigs have shown an association of PIT1 polymorphisms with growth and carcass traits in which the primarily Chinese alleles were associated with heavier birth weight and greater backfat. To further investigate the role of PIT1 in controlling pig growth traits, Chinese Meishan (MS) pigs segregating PIT1 polymorphisms were used to study the differences of GH and PRL at both mRNA and circulating hormone levels. A total of 60 animals from nine litters was used to collect both pituitary and blood samples at day 1, 15, and 30 after birth. A novel procedure that involves standard curve quantification was used to quantify mRNA amount for GH, PRL, PIT1-α, and PIT1-β. Conventional hormone assays were done to measure the circulating amount of GH and PRL from the blood. Statistical analyses of PIT1 genotypes, sex, and days on either mRNA (PIT1 alternative transcripts, GH, and PRL) or circulating hormone (GH and PRL) were done by using the leastsquares procedure. This study investigates GH and PRL at both mRNA and circulating hormone levels in MS pigs segregating PIT1 polymorphisms. Results from this study will provide useful information on the role of PIT1 in controlling pig growth traits

Heat Stress during Pig Oocyte In Vitro Maturation Impacts Embryonic Development and Gene Expression

Gene expression of heat stressed oocytes matured in vitro was evaluated for potential markers which could be used to characterize the effects of heat stress on developing oocytes in the pig. Three heat stress scenarios were administered during in vitro oocyte maturation. Heat stressed oocytes had reduced maturation rates, decreased developmental competency, and altered expression of heat stress and developmental competency markers