Severe Gummy Smile with Class II Malocclusion Treated with LeFort I Osteotomy Combined with Horseshoe Osteotomy and Intraoral Vertical Ramus Osteotomy

In this article, we report the successful surgical treatment of a patient, 34 years of age, who had a severe gummy smile and a class II malocclusion. The patient had an 11-mm gingival exposure during full smile and a convex profile. A LeFort I osteotomy combined with a horseshoe osteotomy was used for the superior repositioning of the maxilla;then, an intraoral vertical ramus osteotomy (IVRO) and genioplasty were performed for mandibular advancement. The maxilla was acceptably impacted 8mm at the first incisor and 5mm at the first molar. Both the occlusion and facial appearance were significantly improved by this surgical-orthodontic treatment. Our results suggest that the combination of a horseshoe osteotomy with a LeFort I osteotomy is a useful technique for reliable superior repositioning of the maxilla

Time-Resolved Observation of Deposition Process of Ultrananocrystalline Diamond/Hydrogenated Amorphous Carbon Composite Films in Pulsed Laser Deposition

Optical emission spectroscopy was used to study pulsed laser ablation of graphite in a hydrogen atmosphere wherein ultrananocrystalline diamond (UNCD)/hydrogenated amorphous carbon (a-C:H) composite films were grown on heated substrates. Time-resolved photographs of a plume that expanded from a laser-irradiation spot toward a substrate were taken using a high-speed ICCD camera equipped with narrow-bandpass filters. While the emissions from C atoms and C2 dimers lasted above the laser-irradiation spot on the target, the emission from C+ ions lasted above the substrate surface for approximately 7 microseconds, although the emission lifetime of species is generally approximately 10 nanoseconds. This implies that C+ ions actively collided with each other above the substrate surface for such a long time. We believe that the keys to UNCD growth in PLD are the supply of highly energetic carbon species at a high density to the substrate and existence of atomic hydrogen during the growth

Ovarian strumal carcinoid: a case report

Background: Carcinoid tumors of the ovary are rare tumors, histopathologically classified as monodermal teratomas and somatic-type tumors arising from dermoid cysts. Their malignancy varies from borderline to malignant. Carcinoid tumors can occur in young and elderly women, and are sometimes seen in mature teratoma, struma ovarii, or mucinous cystadenoma as a nodule or tumor. Strumal carcinoid and mucinous carcinoid present as special types of carcinoid tumors of the ovary. Case report: This report describes a 56-year-old woman who presented with a large pelvic mass on abdominal ultrasonography during a medical examination. The diameter of the pelvic tumor was approximately 11 cm and was suspected to be ovarian cancer. The values of CA125 and CEA were above their reference intervals on preoperative examination. Abdominal total hysterectomy and bilateral salpingo-oophorectomy were performed. Intraoperative frozen-section histopathology suggested a diagnosis of mucinous adenocarcinoma; therefore, partial omentectomy and pelvic lymphadenectomy were also performed. Permanent-section histopathology led to a final diagnosis of strumal carcinoid of the ovary, stage IA (FIGO 2014). Six years post-operation, the patient had no sign of recurrence

Lateral Growth of Uniformly Thin Gold Nanosheets Facilitated by Two-Dimensional Precursor Supply

The nanosheets of highly symmetric materials with a face-centered cubic lattice such as gold have been synthesized by adsorbing the precursors on a flat surface, whose chemical specificity induces the anisotropy of growth rates. We have succeeded in the fabrication of gold nanosheets in a hydrophilic space inside highly separated bilayers, which work as two-dimensional hydrophilic reactors, in a hyperswollen lamellar liquid crystalline phase of an amphiphile solution. One of the physical properties, amphiphilicity, confines the ingredients therein. The nanosheets can only grow in the in-plane direction due to the inhibition of the out-of-plane growth rather than the anisotropy of growth rates probably. Thus, the synthesis can be accelerated; the particles can be completed within 15 min. As not relying on chemical specificity, silver nanosheets could also be synthesized in the same way. The suspension of gold and silver nanosheets without any amphiphiles could be obtained, and the solvent is replaceable. We found that the width of the obtained gold nanosheets is proportional to the Reynolds number of the solution because the area of the bilayer in the hyperswollen lamellar phase depends on shear stress. This implies that the areas of gold nanosheets depend on the areas of the bilayers, and it can be controlled by changing the Reynolds number. This method could be widely used to continuously obtain large-area nanosheets of various materials in a roll-to-roll manufacturing process.Koki Sasaki, suyoshi Okue, Takuto Nakai et al. Lateral Growth of Uniformly Thin Gold Nanosheets Facilitated by Two-Dimensional Precursor Supply. Langmuir, 37 (19), 5872-5877, May 18, © 2021 American Chemical Society. https://doi.org/10.1021/acs.langmuir.1c0034

Thin ZIF-8 nanosheets synthesized in hydrophilic TRAPs

The preparation method of nanosheets using hyperswollen lyotropic lamellar phases, the ‘two-dimensional reactor in amphiphilic phases (TRAP) method’, has successfully provided nanosheets of various non-layered materials. Previously reported examples started from a single hydrophobic or hydrophilic precursor and multiple hydrophobic precursors. Here, we propose a synthesis method of nanosheets of ZIF-8, zinc 2-methylimidazolate, with a sodalite-like framework. They grow up to a few nanometers of thickness and several hundred nanometers of width with neither aggregation nor impurities from multiple hydrophilic precursors in the stoichiometric ratio inside the hydrophilic TRAPs consisting of the amphiphile Brij L4. The thin nanosheets of ZIF-8 doped with Co2+(Co-ZIF-8) synthesized by the same method maintained a high specific surface area after calcination. Therefore, the oxygen reduction reaction (ORR) activity of the calcined Co-ZIF-8 NSs for fuel cells becomes higher than that of the calcined conventional Co-ZIF-8 crystals.Sasaki K., Okue T., Shu Y., et al. Thin ZIF-8 nanosheets synthesized in hydrophilic TRAPs. Dalton Transactions 50, 10394 (2021); https://doi.org/10.1039/d1dt01507a

Establishing allowable value of Electric Conductivity for monitoring groundwater based on the benchmark dose concept and its application

Recently, a number of studies have pointed out that Electric Conductivity (EC) would be a very effective measure for monitoring the quality of ground water possibly polluted by sewage sludge or incineration ash leachate. However, few have explicitly determined the allowable limit of the EC value. Therefore, we have obtained the allowable limit of EC by applying the "benchmark dose (BMO)" method.2010 International Conference on Environmental Engineering and Applications (ICEEA) : Singapore, Singapore, 2010.09.10-2010.09.1

Amorphous Aluminosilicate Nanosheets as Universal Precursors for the Synthesis of Diverse Zeolite Nanosheets for Polymer‐Cracking Reactions

Zeolites catalyze some reactions in their molecular-sized pores, but large molecules can react only on their external surface. Zeolite-nanosheets (NSs) have been developed as catalysts for large molecules. The previously reported methods to synthesize zeolite-NSs are specialized for each zeolite type. Here we propose a new method to synthesize various zeolite-NSs from the same amorphous aluminosilicate NSs (AAS-NSs) as a universal precursor. We successfully synthesized the unprecedented AAS-NSs in the hydrophilic space of the stable hyperswollen lyotropic lamellar (HL) phase. The four zeolite types could be obtained from the single-species AAS-NSs. These results imply that this method enables us to synthesize almost all types of zeolite-NSs. Moreover, the synthesized CHA-NSs have great potential for various applications because of their thickness and large external surface area.Sasaki Koki, Gaitan Jose A. Hernandez, Okue Tsuyoshi, et al. Amorphous Aluminosilicate Nanosheets as Universal Precursors for the Synthesis of Diverse Zeolite Nanosheets for Polymer‐Cracking Reactions. Angewandte Chemie 134, (2022); https://doi.org/10.1002/ange.202213773

Thermal, Mechanical and Physical Properties of Supercooled Liquid in Pd-Cu-Ni-P Amorphous Alloy

The thermal stability, storage modulus (E\u27), loss tangent (tanδ), temperature coefficient of thermal expansion (α) and electrical resistivity of a supercooled liquid were measured for an amorphous Pd_Cu_Ni_P_ alloy with a wide supercooled liquid region before crystallization. The wide supercooled liquid region of 80 K is retained even at the low heating rate of 0.083 K/s. The E\u27 of the supercooled liquid decreases monotonously from 6.0 to 0.35 GPa with increasing temperature from 540 to 590 K and the tanδ increases from 0.07 to 0.52. These changes takes place through a single stage. The α value of the supercooled liquid is measured to be 2.0x10^ K^ which is larger by three orders than that (2.0x10^ K^) for the corresponding amorphous solid. The electrical resistivity decreases through two stages in the range from 2.27 to 2.15 μΩm in the supercooled liquid from 563 to 648 K. These physical and mechanical properties of the supercooled liquid are significantly different from those for the corresponding amorphous solid and important for future development of basic science of supercooled liquid and bulk amorphous alloys

The Transformation Process of Research Awareness as Understood through the Narratives of Students Formerly Enrolled in the Doctoral Program of the Graduate School of Education

　In this study, a qualitative analysis, Trajectory Equifinality Modeling (TEM), was used to highlight the transformation process of the research awareness of four former doctoral students. The doctoral programs to which the students formerly belonged train researchers and professional educators who are capable of research and practice. The authors describe the trajectory of the students advancing to their respective Equifinality Points through various experiences and possibilities despite fluxes in their research awareness. Citing the TEM diagrams drawn, the authors discuss: 1. The existence of change in the research environment and the reality of the adaptation process. 2. The existence of a period of exploration as a practicing researcher. 3. The meaning of the Obligatory Passage Points for students in doctoral programs in education. Closing the article, the authors examine future issues

Determination of topological structure of ARL6ip1 in cells: Identification of the essential binding region of ARL6ip1 for conophylline

AbstractConophylline (CNP) has various biological activities, such as insulin production. A recent study identified ADP-ribosylation factor-like 6-interacting protein 1 (ARL6ip1) as a direct target protein of CNP. In this study, we revealed that ARL6ip1 is a three-spanning transmembrane protein and determined the CNP-binding domain of ARL6ip1 by deletion mutation analysis of ARL6ip1 with biotinyl-amino-CNP. These results suggest that CNP is expected to be useful for future investigation of ARL6ip1 function in cells. Because of the anti-apoptotic function of ARL6ip1, CNP may be an effective therapeutic drug and/or a novel chemosensitizer for human cancers and other diseases