Your mother is not very wise, how do you expect to be any wiser?

Humorous song about a mother not being very wise and therefore the child will not be any wiser, played on guitar and bottle

Your mother is not very wise, how do you expect to be any wiser?

Humorous song about a mother not being very wise and therefore the child will not be any wiser, played on guitar and bottle

Maternal Parenting Stress, Child Exuberance, and Preschoolers' Behavior Problems

This study investigated whether child exuberance, an aspect of temperament related to emotion regulation, moderates the well-documented association between high parenting stress and increased risk for internalizing and externalizing problems during the preschool years. At 42 months of age child exuberance was observed in 256 children (47% girls) and maternal self-reports on parenting stress were obtained. At 48 months internalizing and externalizing problems were assessed through reports from both parents. Indeed, higher maternal parenting stress increased the risk for internalizing problems, and this association was more pronounced among children with high levels of exuberance. Existent emotion regulation difficulties in highly exuberant children may further heighten the risk conveyed by an unfavorable caregiving environment for developing internalizing problems

Pilot Social Feasibility Study for the Establishment of a Public Human Umbilical Cord Blood Stem Cell Bank in South Africa

There is a large unmet need in South Africa for bone marrow transplantation. Umbilical cord blood (UCB) is an important source of stem cells for the treatment of haematological and non-haematological diseases. Access to the two existing private umbilical cord blood stem cell banks (UCB SCBs) in South Africa is limited to individuals that can afford it, which further aggravates the ever increasing divide between families from different socio-economic classes. The problem is compounded by a severe global shortage of genetically compatible samples, representative of the South African demographics. Establishing a public human UCB SCB in South Africa would provide more South Africans with access to previously unavailable treatment in the form of affordable, genetically compatible stem cells for bone marrow transplantation. A public UCB SCB has many facets to consider, one of which is public preparedness and support for the bank. This was assessed in a social feasibility pilot study which is reported here. In addition to the findings of this social feasibility study, other important considerations for establishing a public human UCB SCB in SA include; (a) testing the samples for HIV and other infectious diseases (required for compliance with international regulatory standards); (b) flow cytometric analysis for enumeration of CD34+ UCB stem cells; (c) mapping of HLA genotypes/alleles; and (d) a study of the economic feasibility of this endeavour. The social feasibility study was conducted to gauge public preparedness and support for a public SCB through patient interviews and questionnaires. The process was dynamic due to its novel nature for interviewers and interviewees alike. Many obstacles were met and dealt with which lead to the compilation of results discussed here in the form of a pilot social feasibility study. In the South African context, we are faced with unique and rich challenges relating to cultural and religious differences that are further augmented by linguistic constraints, educational insufficiencies and logistical and administrative limitations. Complicating factors encountered during the informed consent process included cultural differences, religious practices, traditions and superstitions together with language constraints and an educational disparity. Despite many initial obstacles, preliminary results from the informed consent questionnaire were favourable with regard to the establishment of a public UCB SCB. These initial results prompted the revision of the questionnaire and interview process and the compilation of a more succinct and coherent definitive social feasibility study which will form a separate study and which we hope will ultimately assist in the decision of whether or not to establish a public UCB SCB in South Africa. Nevertheless, results from this pilot study appear to be favourable and highlight particular areas which could influence community support for a public SCB. Educating the general public with regard to the workings and benefits of public stem cell banking is the first step in determining the viability of such an undertaking – a unique and rich challenge in the South African context.Medical Research Council (MRC) and the Department of Immunology.http://link.springer.com/journal/12015hb2013ay201

Determination of tsetse challenge and its relationship with trypanosome prevalence in livestock within the African Trypanotolerant Livestock Network

Determines the tsetse challenge and its relationship with trypanosome prevalence in livestock at eleven sites within the African Trypanotolerant Livestock Network. Includes tsetse species, their distribution, habitats, and relative density; trypanosome infection rate; and frequency of vivax and congolense - type infection; also shows the overall tsetse challenge determined from the product of relative density; and tsetse challenge and trypanosome prevalence for trypanotolerant and other cattle herds

Tsetse feeding habits and tsetse challenge at sites of the African Trypanotolerant Livestock Network

Reports the feeding preferences of Glossina species at sites of the African Trypanotolerant Livestock Network. Estimates tsetse challenge and relates the results with trypanosome prevalence in cattle. Examines the relationship between tsetse challenge using linear regression analysis. Also examines the difference between the slopes of the regression lines obtained for trypanotolerant and susceptible cattle using a 't-test'