An unusual case of Multiple Inflammatory Myofibroblastic Tumors of the lung

Inflammatory myofibroblastic tumor (IMT) of the lung is a rare, usually solitary lesion that is considered nowadays as a true neoplasm with unpredictable clinical course. Herein we describe a case of multiple, bilateral IMTs of the lung in a 70 year-old asymptomatic woman, where diagnosis was established by CT guided core biopsy. To our knowledge only 10 cases of bilateral IMTs have been reported in a few case series and in only 2 cases of pulmonary IMTs, CT guided biopsy could establish the correct diagnosis

Embolization of a sporadic bleeding renal angiomyolipoma supplied by an aberrant renal artery

Spontaneous bleeding of a renal angiomyolipoma (AML) is a life threatening condition that necessitates prompt treatment. Herein we describe the first case of a spontaneously ruptured renal AML supplied solely by an aberrant renal artery that was successfully treated by selective transcatherer embolization

Partial Splenic Embolization: Successful treatment of hypersplenism, secondary to biliary cirrhosis and portal hypertension in cystic fibrosis

AbstractPartial Splenic Embolization (PSE) is a non-surgical treatment for hypersplenism. It has been reported only in a limited number of patients with Cystic Fibrosis (CF). We report a case of a female cystic fibrosis patient who developed hypersplenism at the age of 14 and underwent PSE. Long term results over a period of 14 years after the procedure are presented

Adiponectin and body composition in cystic fibrosis

AbstractThe aim of the study was to evaluate adiponectin (AD) serum concentrations in 43 stable CF patients and 27 healthy subjects and to correlate them with their nutritional status. Body Composition (Bioelectrical Impedance), visceral/subcutaneous adipose tissue (VAT-SAT) in CF patients (CT-scan at L4), insulin resistance (HOMA-IR) and AD serum concentrations (ELISA) were studied. CF patients and controls had comparable weight, height, %BF, %FFM, fasting glucose, insulin and insulin resistance. CF patients had significantly lower BMI-SDS. CF males had higher %FFM and total FFM and lower %BF and total BF than females (p<0.001). Serum AD was higher in CF patients than controls (11.53±5.37 vs. 9.07±4.41 μg/ml) and comparable between females and males. AD was lowest among young malnourished patients (8.06±1.85 μg/ml) and highest among young patients with normal nutrition (14.56±7.69 μg/ml). Patients with biliary cirrhosis had higher levels than patients with normal liver (10.52±5.49 vs. 14.04±4.52 μg/ml, p<0.05). AD correlated with %BF, %FFM, FFM (kg) (p<0.05).VAT was significantly increased in malnourished patients. AD was not affected by VAT. Conclusions: Adiponectin is higher in CF patients than healthy individuals. It is decreased in malnourished young patients and increased in patients with normal nutrition and in patients with liver disease. This may be attributed to the reduced BF and to the energy deficit inherent to the disease

Solitary splenic metastasis of squamous lung cancer: a case report

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Cerebral sinus thrombosis in an infant with Prader-Willi syndrome and literature review

A full-term male neonate from a first pregnancy of two clinical non-consanguineous parents was born at 40 weeks of gestation with cesarean section. He was admitted at 2 hours of life to our III level Neonatal Intensive Care Unit due to generalized hypotonia, presenting at birth. Cerebral ultrasound showed a temporal bilateral aspecific alteration of the parenchimal echogenicity, whereas a magnetic resonance imaging/venography revealed an extensive cerebral sinus thrombus. Extensive diagnostic studies for prothrombotic disorders showed negative results, even if there was an alterated haemostatic screening. Persistency of hypotonia led us to investigate Prader-Willi syndrome among others. Methylation analysis confirmed the diagnosis. This is the third report associating cerebral venous thrombosis and Prader-Willi syndrome, confirming sinus thrombosis as a possible presentation of this syndrome. A review of the literature is provided in order to disclose possible similarities and differences in Prader-Willi syndrome patients with cerebral sinovenus thrombosis

Adult type granulosa cell tumor of the testis: Radiological evaluation and review of the literature

A testicular granulosa cell tumor of the adult type is very rare. Isolated case reports and small series have been published in the English literature. Here, we analyze an incidentally discovered testicular granulosa cell tumor in a 29-year-old man to discuss the radiological evaluation of this entity and review the literature