Niobium hyperfine structure in crystal calcium tungstate

A study of the niobium hyperfine structure in single crystal calcium tungstate was made by the combination of the technique of electron paramagnetic resonance and electron nuclear double resonance (EPR/ENDOR). The microwave frequency was about 9.4 GHz and the radio frequency from 20MHz to 70 MHz. The rare earth ions Nd(3+), U(3+), or Tm(3+) were added as the charge compensator for Nb(5+). To create niobium paramagnetic centers, the sample was irradiated at 77 deg K with a 10 thousand curie Co-60 gamma source for 1 to 2 hours at a dose rate of 200 K rads per hour and then transferred quickly into the cavity. In a general direction of magnetic field, the spectra showed 4 sets of 10 main lines corresponding to 4 nonequivalent sites of niobium with I = 9/2. These 4 sets of lines coalesced into 2 sets of 10 in the ab-plane and into a single set of 10 along the c-axis. This symmetry suggested that the tungsten ions are substituted by the niobium ions in the crystal

A very efficient RCS data compression and reconstruction technique, volume 4

A very efficient compression and reconstruction scheme for RCS measurement data was developed. The compression is done by isolating the scattering mechanisms on the target and recording their individual responses in the frequency and azimuth scans, respectively. The reconstruction, which is an inverse process of the compression, is granted by the sampling theorem. Two sets of data, the corner reflectors and the F-117 fighter model, were processed and the results were shown to be convincing. The compression ratio can be as large as several hundred, depending on the target's geometry and scattering characteristics

Mobile Paving System (MPS): A New Large Scale Freeform Fabrication Method

In the last decade, significant opportunities for automation have been identified in the area of construction. Soaring labor and material costs have driven multiple research efforts in construction automation. In this paper, we present a novel means for construction automation that involves the fusion of the rapid prototyping, controls and mechatronics technologies. The resultant autonomous construction mechanism has been designed for commercial applications. Mobile Paving System (MPS) is a new freeform fabrication process which is capable of rapidly producing variable profiles such as curbs and sidewalks out of materials like cement and asphalt. Path generation and guidance of the construction operation is controlled by a mobile robot. This article presents an overview of research and development efforts that are aimed at establishing the feasibility and the potential of the process.Mechanical Engineerin

Heavy-tailed distributions in fatal traffic accidents: role of human activities

Human activities can play a crucial role in the statistical properties of observables in many complex systems such as social, technological and economic systems. We demonstrate this by looking into the heavy-tailed distributions of observables in fatal plane and car accidents. Their origin is examined and can be understood as stochastic processes that are related to human activities. Simple mathematical models are proposed to illustrate such processes and compared with empirical results obtained from existing databanks.Comment: 10 pages, 5 figure

Reaching Approximate Byzantine Consensus with Multi-hop Communication

We address the problem of reaching consensus in the presence of Byzantine faults. In particular, we are interested in investigating the impact of messages relay on the network connectivity for a correct iterative approximate Byzantine consensus algorithm to exist. The network is modeled by a simple directed graph. We assume a node can send messages to another node that is up to $l$ hops away via forwarding by the intermediate nodes on the routes, where $l\in \mathbb{N}$ is a natural number. We characterize the necessary and sufficient topological conditions on the network structure. The tight conditions we found are consistent with the tight conditions identified for $l=1$, where only local communication is allowed, and are strictly weaker for $l>1$. Let $l^*$ denote the length of a longest path in the given network. For $l\ge l^*$ and undirected graphs, our conditions hold if and only if $n\ge 3f+1$ and the node-connectivity of the given graph is at least $2f+1$ , where $n$ is the total number of nodes and $f$ is the maximal number of Byzantine nodes; and for $l\ge l^*$ and directed graphs, our conditions is equivalent to the tight condition found for exact Byzantine consensus. Our sufficiency is shown by constructing a correct algorithm, wherein the trim function is constructed based on investigating a newly introduced minimal messages cover property. The trim function proposed also works over multi-graphs.Comment: 24 pages, 1 figure. arXiv admin note: text overlap with arXiv:1203.188

Steady, oscillatory, and unsteady subsonic Aerodynamics, production version 1.1 (SOUSSA-P1.1). Volume 2: User/programmer manual

A user/programmer manual for the computer program SOUSSA P 1.1 is presented. The program was designed to provide accurate and efficient evaluation of steady and unsteady loads on aircraft having arbitrary shapes and motions, including structural deformations. These design goals were in part achieved through the incorporation of the data handling capabilities of the SPAR finite element Structural Analysis computer program. As a further result, SOUSSA P possesses an extensive checkpoint/ restart facility. The programmer's portion of this manual includes overlay/subroutine hierarchy, logical flow of control, definition of SOUSSA P 1.1 FORTRAN variables, and definition of SOUSSA P 1.1 subroutines. Purpose of the SOUSSA P 1.1 modules, input data to the program, output of the program, hardware/software requirements, error detection and reporting capabilities, job control statements, a summary of the procedure for running the program and two test cases including input and output and listings are described in the user oriented portion of the manual

On the Boundary Entropy of One-dimensional Quantum Systems at Low Temperature

The boundary beta-function generates the renormalization group acting on the universality classes of one-dimensional quantum systems with boundary which are critical in the bulk but not critical at the boundary. We prove a gradient formula for the boundary beta-function, expressing it as the gradient of the boundary entropy s at fixed non-zero temperature. The gradient formula implies that s decreases under renormalization except at critical points (where it stays constant). At a critical point, the number exp(s) is the ``ground-state degeneracy,'' g, of Affleck and Ludwig, so we have proved their long-standing conjecture that g decreases under renormalization, from critical point to critical point. The gradient formula also implies that s decreases with temperature except at critical points, where it is independent of temperature. The boundary thermodynamic energy u then also decreases with temperature. It remains open whether the boundary entropy of a 1-d quantum system is always bounded below. If s is bounded below, then u is also bounded below.Comment: 12 pages, Latex, 1 eps-figure; v2: some expository material added, a slightly more condensed version of the paper is publihed in Phys. Rev. Let

Response Detection of Castrate-Resistant Prostate Cancer to Clinically Utilised and Novel Treatments by Monitoring Phospholipid Metabolism

The authors gratefully acknowledge funding from Grampian NHS Endowment. The use of Professor Zanda’s and Jaspar’s NMR equipment and Russell Gray’s assistance are also gratefully acknowledged.Peer reviewedPublisher PD

Profile of etravirine for the treatment of HIV infection

Etravirine is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with the advantages of in vitro potency against many strains of virus resistant to efavirenz and nevirapine, as well as a higher genetic barrier to resistance. Etravirine is indicated for use in treatment-experienced patients, and the approved dose in adults is 200 mg twice daily. Etravirine should be administered after a meal as bioavailability is significantly reduced when taken in the fasting state. Etravirine is a substrate of CYP3A4, CYP2C9, CYP2C19, and uridine diphosphate glucuronyltransferase, and induces CYP3A4, weakly inhibits CYP2C9 and moderately inhibits CYP2C19. Etravirine may be coadministered with nucleoside/tide reverse transcriptase inhibitors, raltegravir and boosted darunavir, lopinavir, and saquinavir without dosage adjustment. Etravirine should not be given with other NNRTIs, unboosted protease inhibitors, and atazanavir/ritonavir, tipranavir/ritonavir, and fosamprenavir/ritonavir due to unfavorable drug interactions. In randomized, controlled trials, twice daily etravirine combined with darunavir/ritonavir plus optimized background therapy demonstrated better efficacy compared to darunavir/ritonavir plus optimized background therapy alone in treatment-experienced populations out to 96 weeks follow-up. The main etravirine-associated toxicity is mild to moderate self-limiting rash, although severe and sometimes fatal hypersensitivity reactions have been reported. Etravirine offers a potent sequencing option after the development of resistance to first-line NNRTIs, and is a welcome addition to this established drug class