Justification of the wood polymer material application conditions

The production of heat-insulating materials based on wood was analyzed in this paper. The expediency and efficiency of using wood waste were established. A study of the operational properties of the sample obtained from wood shavings polymerized with mixtures of polyester and epoxy resins was carried out. It was proven that the process’s primary regulator is the material’s density and porosity. Also, an increase in humidity and wetting reduces heat-insulating indicators. Based on thermophysical dependences, the thermal insulation properties of the samples were calculated. Moreover, it was established that the thermal conductivity does not exceed 0.21·10–6 m2 /s, and the thermal conductivity of the sample – 2.85·10–3 W/(m·K). Therefore, these products can be classified as heatinsulating materials. A through-thickness compressive strength study showed that the wood shavings and polyester resin material are more fragile, and the strength limit was reduced by more than 1.2 times compared to the epoxy resin-based material. The moisture absorption results showed that a heat-insulating product made of shavings polymerized with polyester resin. Moisture absorption was 5 % after 90 days of exposure to water. On the other hand, the heat-insulating products made of shavings with epoxy resin of 4.41 % showed their resistance to moisture absorption

Identification of inhibitors targeting the energy-coupling factor (ECF) transporters

The energy-coupling factor (ECF) transporters are a family of transmembrane proteins involved in the uptake of vitamins in a wide range of bacteria. Inhibition of the activity of these proteins could reduce the viability of pathogens that depend on vitamin uptake. The central role of vitamin transport in the metabolism of bacteria and absence from humans make the ECF transporters an attractive target for inhibition with selective chemical probes. Here, we report on the identification of a promising class of inhibitors of the ECF transporters. We used coarse-grained molecular dynamics simulations on Lactobacillus delbrueckii ECF-FolT2 and ECF-PanT to profile the binding mode and mechanism of inhibition of this novel chemotype. The results corroborate the postulated mechanism of transport and pave the way for further drug-discovery efforts.</p

Customer Relationship Management through the Eyes of the Customers

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