Demographics for the study subjects per group.

<p>Demographics for the study subjects per group.</p

Mean pre-to-post-Tx differences in dopamine transporter binding.

<p>Mean pre-to-post-Tx differences in dopamine transporter binding.</p

Mean pre- and post-Tx UPDRS Total Score.

<p>Mean pre- and post-Tx UPDRS Total Score.</p

N-Acetyl Cysteine May Support Dopamine Neurons in Parkinson's Disease: Preliminary Clinical and Cell Line Data - Fig 3

<p>Pre and post NAC DaTscans (left and right respectively) from one particularly responsive patient (A) shows a substantial increase in dopamine transporter binding in the basal ganglia (arrows). We also present (B) the paired t test results overlaid onto a standard MRI template using SPM8 software showing significantly greater binding (p<0.05) post NAC in the basal ganglia.</p

CONSORT Flow Diagram.

<p>CONSORT Flow Diagram.</p

mDA neurons derived from hESCs were treated with N-acetyl cysteine at 10 μM for 3 days before challenge with rotenone (15nM and 30 nM) for 24 hours.

<p>TH+ neurons were quantified after cells were fixed and stained. Data was normalized as percentage of surviving mDA neurons compared to untreated control (100%). Treatment groups were compared with rotenone only groups using unpaired t-test. * p<0.05, ** p<0.01.</p

Mean pre- and post-Tx dopamine transporter binding measures.

<p>Mean pre- and post-Tx dopamine transporter binding measures.</p

Significant predictors of UPDRS Total Score.

<p>Significant predictors of UPDRS Total Score.</p