4,442 research outputs found

    Enhanced call quality using user-specific voiceprint model

    Get PDF
    The audio quality of a call conducted using a user device such as a phone can be unsatisfactory due to a variety of reasons. Such reasons include noisy surroundings at the location from which the user conducts a call, position of the phone near the user’s face, users that speak with a soft voice, presence of far-end echoes, etc. This disclosure describes techniques that use a user-specific voiceprint to home into the user’s speech and cut out surrounding disturbances from a voice call. The techniques are implemented with user permission to generate and use the voiceprint

    Rainfall Reliability Evaluation for Stability of Municipal Solid Waste Landfills on Slope

    Get PDF
    [[abstract]]A method to assess the reliability for the stability of municipal solid waste (MSW) landfills on slope due to rainfall infiltration is proposed. Parameter studies are first done to explore the influence of factors on the stability of MSW. These factors include rainfall intensity, duration, pattern, and the engineering properties of MSW. Then 100 different combinations of parameters are generated and associated stability analyses of MSW on slope are performed assuming that each parameter is uniform distributed around its reason ranges. In the following, the performance of the stability of MSW is interpreted by the artificial neural network (ANN) trained and verified based on the aforementioned 100 analysis results. The reliability for the stability of MSW landfills on slope is then evaluated and explored for different rainfall parameters by the ANN model with first-order reliability method (FORM) and Monte Carlo simulation (MCS).[[incitationindex]]SCI[[booktype]]紙

    DNA Methylation in Aggressive Gastric Carcinoma

    Get PDF

    miRNAs in Gastric Cancer

    Get PDF

    Desilting Efficiency Due to Empty Flushing of Agongdian Reservoir

    Get PDF
    Source: ICHE Conference Archive - https://mdi-de.baw.de/icheArchive

    Sequence features involved in the mechanism of 3' splice junction wobbling

    Get PDF
    Background Alternative splicing is an important mechanism mediating the diversified functions of genes in multicellular organisms, and such event occurs in around 40-60% of human genes. Recently, a new splice-junction wobbling mechanism was proposed that subtle modifications exist in mRNA maturation by alternatively choosing at 5'- GTNGT and 3'- NAGNAG, which created single amino acid insertion and deletion isoforms. Results By browsing the Alternative Splicing Database information, we observed that most 3' alternative splice site choices occur within six nucleotides of the dominant splice site and the incidence significantly decreases further away from the dominant acceptor site. Although a lower frequency of alternative splicing occurs within the intronic region (alternative splicing at the proximal AG) than in the exonic region (alternative splicing at the distal AG), alternative AG sites located within the intronic region show stronger potential as the acceptor. These observations revealed that the choice of 3' splice sites during 3' splicing junction wobbling could depend on the distance between the duplicated AG and the branch point site (BPS). Further mutagenesis experiments demonstrated that the distance of AG-to-AG and BPS-to-AG can greatly influence 3' splice site selection. Knocking down a known alternative splicing regulator, hSlu7, failed to affect wobble splicing choices. Conclusion Our results implied that nucleotide distance between proximal and distal AG sites has an important regulatory function. In this study, we showed that occurrence of 3' wobble splicing occurs in a distance-dependent manner and that most of this wobble splicing is probably caused by steric hindrance from a factor bound at the neighboring tandem motif sequence
    corecore