1,233 research outputs found
A Study of Online Information Search and Experience Goods from Travel and Tourism Perspective
This study investigated consumer behaviour in online travel information search. Based on Engel-Kollat-Blackwell Model, ATR and TAM theory, the study was designed to discover similarities and differences between European and Asian students in pre-purchase, purchase and post-purchase stages. The study was conducted by qualitative research; a semi-structured interview was selected to be the research method, in order to unearth more detailed data through flexible conversation. According to the findings, European and Asian students have similar perspectives on the six selected determinants influencing the attitude towards the use of the Internet, including the perceived usefulness, the perceived ease of use, previous experience, others’ opinions, online security and inconsistency. Besides, the students in both groups are proved to have a repeating search habit. Despite the similarities, students from Europe and Asia have different travel information sources and searching purposes. While Asian students tend to use online travel information for a specific trip, European search for the information not only for trips but also for fun and social. Asian students also use guide books as alternative sources more often. In addition, Asian students may encounter more difficulties than their European counterparts due to the deficiency in the language backgrounds
Graphic-Card Cluster for Astrophysics (GraCCA) -- Performance Tests
In this paper, we describe the architecture and performance of the GraCCA
system, a Graphic-Card Cluster for Astrophysics simulations. It consists of 16
nodes, with each node equipped with 2 modern graphic cards, the NVIDIA GeForce
8800 GTX. This computing cluster provides a theoretical performance of 16.2
TFLOPS. To demonstrate its performance in astrophysics computation, we have
implemented a parallel direct N-body simulation program with shared time-step
algorithm in this system. Our system achieves a measured performance of 7.1
TFLOPS and a parallel efficiency of 90% for simulating a globular cluster of
1024K particles. In comparing with the GRAPE-6A cluster at RIT (Rochester
Institute of Technology), the GraCCA system achieves a more than twice higher
measured speed and an even higher performance-per-dollar ratio. Moreover, our
system can handle up to 320M particles and can serve as a general-purpose
computing cluster for a wide range of astrophysics problems.Comment: Accepted for publication in New Astronom
Sonographic Detection of Pseudoaneurysm in Vascular Injury in Emergency Department
A 31-year-old man suffered from a stab wound to the lower extremity. The patient had a hard sign of a vascular injury (a diminished distal pulse) and therefore probably should have undergone operative repair, but refused. One week later, he returned to our emergency department with a painful right thigh swelling. Bedside sonography was used to detect a pseudoaneurysm. Emergency sonography is a fast, non-invasive, and rapid decision-making approach in emergency practice
Isolation and characterization of stromal progenitor cells from ascites of patients with epithelial ovarian adenocarcinoma
<p>Abstract</p> <p>Background</p> <p>At least one-third of epithelial ovarian cancers are associated with the development of ascites containing heterogeneous cell populations, including tumor cells, inflammatory cells, and stromal elements. The components of ascites and their effects on the tumor cell microenvironment remain poorly understood. This study aimed to isolate and characterize stromal progenitor cells from the ascites of patients with epithelial ovarian adenocarcinoma (EOA).</p> <p>Methods</p> <p>Seventeen ascitic fluid samples and 7 fresh tissue samples were collected from 16 patients with EOA. The ascites samples were then cultured in vitro in varying conditions. Flow cytometry and immunocytochemistry were used to isolate and characterize 2 cell populations with different morphologies (epithelial type and mesenchymal type) deriving from the ascites samples. The in vitro cell culture model was established using conditional culture medium.</p> <p>Results</p> <p>The doubling times of the epithelial type and mesenchymal type cells were 36 h and 48 h, respectively, indicating faster growth of the epithelial type cells compared to the mesenchymal type cells. Cultured in vitro, these ascitic cells displayed the potential for self-renewal and long-term proliferation, and expressed the typical cancer stem/progenitor cell markers CD44<sup>high</sup>, CD24<sup>low</sup>, and AC133<sup>+</sup>. These cells also demonstrated high BMP-2, BMP4, TGF-β, Rex-1, and AC133 early gene expression, and expressed EGFR, integrin α<sub>2</sub>β<sub>1</sub>, CD146, and Flt-4, which are highly associated with tumorigenesis and metastasis. The epithelial type cells demonstrated higher cytokeratin 18 and E-cadherin expression than the mesenchymal type cells. The mesenchymal type cells, in contrast, demonstrated higher AC133, CD73, CD105, CD117, EGFR, integrin α<sub>2</sub>β<sub>1</sub>, and CD146 surface marker expression than the epithelial type cells.</p> <p>Conclusion</p> <p>The established culture system provides an in vitro model for the selection of drugs that target cancer-associated stromal progenitor cells, and for the development of ovarian cancer treatments.</p
A case of acute appendicitis with Vibrio fluvialis peritonitis
AbstractHuman infections caused by Vibrio fluvialis are rarely reported. The most common clinical presentation of V. fluvialis infection is acute gastroenteritis with diarrhea. Reported extra-intestinal infections caused by V. fluvialis have included bacteremia, hemorrhagic cellulitis and cerebritis. Peritonitis is an uncommon clinical presentation of Vibrio infections, and most cases have occurred in patients receiving peritoneal dialysis or those with liver cirrhosis. Herein, we report the first case of acute appendicitis with V. fluvialis peritonitis
Inflammatory Marker but Not Adipokine Predicts Mortality among Long-Term Hemodialysis Patients
Aims: chronic inflammation contributes significantly to the morbidity and mortality of chronic hemodialysis patients. A recent research has shown that adipokines were associated with inflammation in these patients. We aim to investigate whether biomarkers of inflammation, adipokines, and clinical features can predict the outcome of hemodialysis patients. Materials and methods: we enrolled 181 hemodialysis patients (men: 97, mean age: 56.3±13.6) and analyzed predictors of long-term outcomes. Results: during the 3-year followup period, 41 patients died; the main causes of death were infection and cardiovascular disease. Elevated serum levels of hsCRP and albumin and advanced age were highly associated with death
(all P<.001). Leptin and adiponectin levels were not significantly different between deceased patients and survivors. Cox-regression analysis indicated that age, diabetes, albumin level, and hsCRP were independent factors predicting mortality. Conclusion: the presence of underlying disease, advanced age, and markers of chronic inflammation is strongly related to survival rate in long-term hemodialysis patients
Clinical characteristics and treatment outcomes of patients with tubo-ovarian abscess at a tertiary care hospital in Northern Taiwan
Background/PurposeControversy exists regarding the need for surgical intervention in patients with tubo-ovarian abscess (TOA). This study was aimed at investigating the clinical characteristics and treatment outcomes in patients with TOA at a tertiary care hospital in Taiwan.MethodsThe medical records of 83 patients who presented at the hospital with TOA between January 1, 2006, and December 31, 2007, were retrospectively reviewed. Outcomes of patients who received medical treatment alone or underwent surgical intervention were analyzed using univariate and logistic regression analyses.ResultsAmong the 83 patients with TOA, 13 patients (15.7%) underwent surgical intervention, and 70 patients (84.3%) received medical treatment alone. Significant variables related to surgical treatment in the univariate analysis were length of stay (short vs. long; t = −2.267, p = 0.026), department of admission (emergency room vs. outpatient department; χ2 = 7.459, p = 0.006), number of live births (nulliparous vs. multiparous; χ2 = 18.202, p = 0.001), and C-reactive protein (CRP) level (high vs. low; t = −2.250, p = 0.028). Logistic regression analysis performed to determine influential factors for surgical treatment showed that the operation odds ratio of three to four live births versus no live births was 33.995 (p = 0.043) and that of two live births versus no live births was 13.598 (p = 0.026).ConclusionPatients with TOA who underwent surgery had a longer duration of hospitalization. Among the patients who underwent surgical intervention, those admitted to the emergency room had higher CRP levels and were more likely to be multiparous
Influence of Socioeconomic Factors, Gender and Indigenous Status on Smoking in Taiwan.
The indigenous Austronesian minority of Taiwan is heavily affected by health disparities which may include suffering from a greater burden of the tobacco epidemic. While a lack of representative data has historically precluded an investigation of the differences in smoking between Taiwanese ethnicities, these data have recently become available through an annual population-based telephone survey conducted by the Health Promotion Administration, Ministry of Health and Welfare (previously known as the Bureau of Health Promotion (BHP), Department of Health). We used the BHP monitoring data to observe the prevalence of smoking and environmental tobacco smoke exposure among indigenous and non-indigenous Taiwanese surrounding a tobacco welfare tax increase in 2006, investigate ethnic differences in smoking prevalence and environmental tobacco smoke exposure each year between 2005 and 2008, and perform multiple logistic regression to estimate measures of association between potential risk factors and smoking status. Despite significant ethnic and gender differences in smoking prevalence, smoking status was not found to be significantly associated with ethnicity after controlling for socioeconomic and demographic factors
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