Two-dimensional density plot of novel genome 'specific genes' for the pan-genome

<p><b>Copyright information:</b></p><p>Taken from "Characterization of probiotic isolates with a novel pan-genome microarray"</p><p>http://genomebiology.com/2007/8/12/R267</p><p>Genome Biology 2007;8(12):R267-R267.</p><p>Published online 18 Dec 2007</p><p>PMCID:PMC2246269.</p><p></p> The plot illustrates the number of novel genome specific genes for the nth genome when comparing = 2,...,32 genomes (for a maximum of 3,200 random combinations at each n). The density colors reflect the count of combinations giving rise to a certain number of specific genes (y-axis) in one genome compared to n - 1 other genomes; that is, for = 2, genome number 2 is compared to genome number 1 and, on average, approximately 650 genes are found to be specific to strain 2. The blue line is the fit to the originally suggested exponential decay function [3]

Hierarchical cluster analysis of hybridization signals from the samples summarized in Table 4, including control samples

<p><b>Copyright information:</b></p><p>Taken from "Characterization of probiotic isolates with a novel pan-genome microarray"</p><p>http://genomebiology.com/2007/8/12/R267</p><p>Genome Biology 2007;8(12):R267-R267.</p><p>Published online 18 Dec 2007</p><p>PMCID:PMC2246269.</p><p></p> The analysis is based on remaining probes (refer to Materials and methods for details) after filtering and removal of probes in gene groups with three or less probes. For clustering, the '1-pearson correlation' distance metric was used

Hierarchical cluster analysis of the 32 design genomes according to gene absence or presence based on the design (normal font)

<p><b>Copyright information:</b></p><p>Taken from "Characterization of probiotic isolates with a novel pan-genome microarray"</p><p>http://genomebiology.com/2007/8/12/R267</p><p>Genome Biology 2007;8(12):R267-R267.</p><p>Published online 18 Dec 2007</p><p>PMCID:PMC2246269.</p><p></p> The four Symbioflor2 isolates as well as the two control strains are included in the dendrogram (bold font) by clustering them according to gene predictions based on the sample hybridizations. For clustering, the Euclidian distance metric was used