9 research outputs found
SCYX-7158, an Orally-Active Benzoxaborole for the Treatment of Stage 2 Human African Trypanosomiasis
- Author
- B Nare
- B Raz
- Bakela Nare
- Beth Beaudet
- BF Krippendorff
- BN Ames
- Charles Ding
- Cindy Rewerts
- CJ Bacchi
- CJ Bacchi
- CJ Bacchi
- CJ Price
- Cyrus J. Bacchi
- D Ding
- Daitao Chen
- DJ Grab
- EI Nielsen
- EM Fèvre
- Eric Gaukel
- F Checchi
- FJ Murray
- FW Jennings
- G Priotto
- G Priotto
- H Hirumi
- Ivan Scandale
- J Atouguia
- J Opigo
- JA Frearson
- Jacob J. Plattner
- Jennifer Keiser
- Jennifer Owens
- Jessica M. Sligar
- JW Polli
- KM Mahar Doan
- Luke T. Mercer
- M Mueller
- Marcel Kaiser
- Matthew D. Orr
- Matthew X. Jenks
- MC Sanguinetti
- MD Troutman
- MP Barrett
- Nigel Yarlett
- O Yun
- PH Beaune
- PP Simarro
- Reto Brun
- Robert A. Noe
- Robert Don
- Robert T. Jacobs
- Robin Parham
- RTNB Jacobs
- Ryan Randolph
- S Mohammad
- SL Croft
- SR Wilkinson
- Stephen A. Wring
- T Baltz
- Tana S. Bowling
- Tsutomu Akama
- VE Thiel-Demby
- VE Thiel-Demby
- Y.-K. Zhang
- Yvonne Freund
- Z Zhou
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2011
- Field of study
Human African trypanosomiasis (HAT) is caused by infection with the parasite Trypanosoma brucei and is an important public health problem in sub-Saharan Africa. New, safe, and effective drugs are urgently needed to treat HAT, particularly stage 2 disease where the parasite infects the brain. Existing therapies for HAT have poor safety profiles, difficult treatment regimens, limited effectiveness, and a high cost of goods. Through an integrated drug discovery project, we have discovered and optimized a novel class of boron-containing small molecules, benzoxaboroles, to deliver SCYX-7158, an orally active preclinical drug candidate. SCYX-7158 cured mice infected with T. brucei, both in the blood and in the brain. Extensive pharmacokinetic characterization of SCYX-7158 in rodents and non-human primates supports the potential of this drug candidate for progression to IND-enabling studies in advance of clinical trials for stage 2 HAT
Subacute changes in defibrillation threshold following multiprogrammable derbrillator implantation in man
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Amiodarone or an Implantable Cardioverter–Defibrillator for Congestive Heart Failure
- Author
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- Field of study
Refining the In Vitro and In Vivo Critical Parameters for P-Glycoprotein, [I]/IC 50
- Author
- Acharya P.
- Balimane P. V.
- Bauman J. L.
- Bo Feng
- Bottiger Y.
- Boyd R. A.
- Caroline A. Lee
- Charles Rotter
- Choo E. F.
- Dennis A. Smith
- Dey S.
- Ding R.
- Dorian P.
- Dupont A. G.
- Eichler H. G.
- Ekins S.
- Faessel H. M.
- Fawcett T.
- Feng B.
- Feng B.
- Fenner K. S.
- Homolya L.
- Jack A. Cook
- Jalava K. M.
- Kalvass J. C.
- Katherine S. Fenner
- Keogh J. P.
- Kirch W.
- Kirimli O.
- Kleinermans D.
- Kullak-Ublick G. A.
- Lindenbaum J.
- Loi C. M.
- Matthew D. Troutman
- Mikkaichi T.
- Mohammed Ullah
- Muller H.
- Piergies A. A.
- Polli J. W.
- Purkins L.
- Rautio J.
- Ray Liu
- Rodin S. M.
- Roman D.
- Sahi J.
- Sarah Kempshall
- Scala S.
- Shapiro A. B.
- Takara K.
- Tang F.
- The Digitalis Investigation Group
- Tiberghien F.
- Tolbert D. S.
- Tran T. T.
- Troutman M. D.
- Tuncok Y.
- Wang E.
- Westphal K.
- Wyse D. G.
- Zhang L.
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- Field of study
Robert Monroe Harrison, British Abolition, Southern Anglophobia and Texas Annexation
- Author
- Brown Bertram Wyatt.
- Brown Bertram Wyatt.
- Calhoun John C.
- Calhoun John C.
- Calhoun John C.
- Cooper Jr.
- Davis David Brion.
- Dellamura Fred A.
- Edward B. Rugemer
- Eltis David
- Everett Alexander
- Everett Alexander
- Faust Drew Gilpin
- Faust Drew Gilpin
- Fehrenbacher Don E.
- Freehling William
- Frucht Richard
- Gurney Joseph John
- Hall Claude H.
- Haynes Sam W.
- Hietala Thomas
- Jennings Lawrence C.
- Jones Howard
- Macqueen James
- Manning William R.
- Meriwhether Robert L.
- Merk Frederick
- Merk Frederick
- Murray David R.
- Nevins Allan
- Niven John
- Peterson Norma Lois.
- Pletcher David
- Sale Maggie Montesinos
- Shenton James P.
- Smith Justin H.
- Staudenraus P. J.
- Tadman Michael
- Tise Larry
- Troutman Phillip
- Turnbull David
- Turner Mary
- Wiltse Charles M.
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Judicial Reform in Florida, 1970-2000: Voters’ Responses to Referenda Across Time
- Author
- -Judge Zack
- Additionally
- Alan T Diamond
- Allen Morris
- Aubrey W Jewett
- B K Roberts
- Baker V
- Benjamin Ginsburg
- Betty H Zisk
- Celeste Muir
- Charles S Bullock
- Clive W J Granger
- D&apos
- D&apos
- Damodar N Gujarati
- David B Magelby
- David Easton
- David Easton
- Drew Lanier
- Earl Black
- Earl Black
- Edward J Gurney
- Fletcher G Rush
- Florida Statutes
- Gerald F Richman
- Gerald M Pomper
- Halbert White
- Harold W Stanley
- Henry R Glick
- Henry R Glick
- Herman J Russomanno
- Howard Troxler
- J Durbin
- James A Stimson
- James A Urban
- James M Vanderleeuw
- James Q Wilson
- Jay S Goodman
- Joel A Thompson
- John D Felice
- John F Harkness
- Kevin A Hill
- Kevin M Esterling
- Lanier Hurwitz
- Larry Bartels
- Leonard H Gilbert
- Leonard H Gilbert
- Lester W Milbrath
- Louis Jacobson
- Madison B Mcclellan
- Marsha Puro
- Mary L Volcansek
- Melinda Hall
- Michael Barone
- Nathaniel Beck
- Nathaniel Beck
- Norman C Thomas
- Paul Beck
- Paul Brace
- Peter H Russell
- Philip L Dubois
- Philip L Dubois
- Philip L Dubois
- Raymond E Wolfinger
- Reynolds V Sims
- Robert J Friedrich
- Roger Handberg
- Roger Handberg
- Roger Handberg
- Russell Troutman
- See Lanier
- See Reynolds V
- Shaun Bowler
- Sidney Verba
- Suzanna Deboef
- Suzanne Parker
- Thomas
- Thomas R Dye
- Thomas R Dye
- U S Bureau
- U S Bureau
- U S Bureau
- U S Bureau
- U S Bureau
- U S Bureau
- U S Bureau
- U S Bureau
- U S Bureau
- W Douglass
- W Smith
- Walter Burnham
- Wesberry V Sanders
- Wesberry V Sanders
- William C Havard
- William H Flangian
- Zisk
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2011
- Field of study
A Review of the Literature on Ministry Transfer
- Author
- Allen Roland
- Allen Wayne
- Armstrong Philip E.
- Baba Panya
- Bavnick J. H.
- Beyerhaus Peter
- Bolman Lee G.
- Bonk Jonathan J.
- Bowers Robert
- Bruce F. F.
- Clark Dennis E.
- Conn Harvie M.
- Corbett Steve
- Costas Orlando E.
- Dominguez Arsenio
- Estes Steven
- Fuller W. Harold
- Havermale Lewis F.
- Hay Alexander R.
- Hay Ian M.
- Hesselgrave David J.
- Hiebert Paul
- Hodges Melvin L.
- Hodges Melvin L.
- Hollis Michael
- Houghton Graham W.
- Hung Daniel M.
- Kane J. Herbert
- King Louis L.
- King Louis L.
- Knight William
- Kopp Dwight A.
- Kornfield William J.
- Kornfield William J.
- Langford Sydney
- Larson Alfred
- Lawal Julius Baamidele
- Lingenfelter Sherwood
- Mangham T. Grady
- McGavran Donald Anderson
- McQuilkin J. Robertson
- Mumper Sharon
- Mumper Sharon
- Murdock Steve
- Neill Stephen
- Neill Stephen
- Nevius John L.
- Nevius John L.
- Nida Eugene A.
- Nida Eugene A.
- O'Connor Patrick
- Patterson George
- Patterson George
- Read William R.
- Rickett Daniel
- Roundhill Ken S.
- Schwartz Glenn
- Schwartz Glenn
- Schwartz Glenn J.
- Shenk Wilbert R.
- Soltau T. Stanley
- Spruth Edwin L.
- Stam Peter
- Stanley Rajamani
- Steffen Tom A.
- Steffen Tom A.
- Sweeney Ernest S.
- Thompson J. Allen
- Thornton W. Philip
- Tippett A. R.
- Troutman Charles H.
- Venn H.
- Wagner C. Peter
- Wagner C. Peter
- Wakatama Pius
- Webster Warren
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study
The History of Microsurgery
- Author
- A Arakaki
- A Carrel
- A David
- A Elander
- A Fukui
- A Lapchinsky
- A Nystrom
- A Paré
- AF Charles
- AJ Welland
- AK Jain
- AL Beek Van
- AM Feller
- AT Tellioglu
- B Strauch
- BE Cohen
- BM O’Brien
- BM O’Brien
- BM O’Brien
- C Braun
- C Champisi
- C. Champisi
- CA Staley
- CC Guthrie
- CC Snyder
- CH Lin
- CO Nylen
- CR Garcia
- CR Stirrat
- CV Thomas
- CW Chen
- D Buck-Gramcko
- DA Hidalgo
- DC Chuang
- DG Pennington
- DH McLean
- DT Chui
- DW Furnas
- DW McCullough
- E Biemer
- E Biemer
- E Höphner
- E Lexer
- ER Owen
- ER Stephenson Jr
- FA Valauri
- FA Valauri
- FA Valauri
- FC Wei
- FC Wei
- FJ Camacho
- FW Bora
- G Brunelli
- G Foucher
- G Foucher
- G Holmgren
- GD Lister
- GHD Miller
- GI Taylor
- GI Taylor
- GI Taylor
- GI Taylor
- GI Taylor
- H Anderl
- H Harms
- H Kawabata
- H Littmann
- H Margossian
- H Margossian
- H Millesi
- H Millesi
- H Nakajima
- H Samii
- H.E. Kleinert
- Hallowell
- HB Williams
- HB Williams
- HC Meuli
- HE Kleinert
- HE Kleinert
- HJ Buncke
- HJ Buncke
- HJ Buncke
- HJ Buncke
- HJ Buncke
- HJ Buncke
- HJ Goald
- I Koshima
- I Koshima
- I Koshima
- IA McGregor
- J Baudet
- J Goyanes
- J Ito
- J McLean
- JB Jupiter
- JB Jupiter
- JB Murphy
- JH Jacobson
- JH Jacobson
- JH Spiegel
- JI Barraquer
- JK Terzis
- JK Terzis
- JM Dubernard
- JM Siliski
- Jones
- JP Daigle
- JR Cobbett
- JR Cobbett
- JR Urbaniak
- JR Urbaniak
- JS Taras
- JW Smith
- JW Smith
- JW Tupper
- JY Bao
- K Doi
- K Doi
- K Doi
- K Doi
- K Doi
- K Doi
- K Harii
- K Harii
- K Harii
- K Harii
- K Harii
- K Swolin
- K.E. Bos
- L Clodius
- L Gordon
- L.T. Oestrup
- LB Gayle
- LI Malis
- LI Malis
- LM Nolan
- LT Ostrup
- M Godina
- M Schoofs
- M Usui
- M Usui
- M Yoshimura
- M Yoshimura
- MG Yasargil
- MI Boyer
- N Kimura
- NF Jones
- NJ James
- NK Poppen
- NV Eck
- P Gloviczki
- PJ Hurwitz
- R Winston
- R.T. Manktelow
- RA Malt
- RB Hamilton
- RC Russell
- RC Troutman
- RD Acland
- RD Goldner
- Research Laboratory for Replantation of Severed Limb Shanghai Sixth Peoples Hospital
- RH Ablove
- RK Daniel
- RK Khouri
- RL Walton
- RM Goldwyn
- RMP Donaghy
- RP Ferrari
- RT Manktelow
- RW Hakstian
- RW Rand
- RW Williams
- S Komatsu
- S Lee
- S Lee
- S Lee
- S Lee
- S Lee
- S Lee
- S Lee
- S Lee
- S Tamai
- S Tamai
- S Tamai
- S Tamai
- S Tamai
- S Tamai
- S.M. Braek
- SH Lee
- SJ Silver
- SJ Silver
- SK Vilkki
- SK Vilkki
- SP Chow
- T Fujino
- T Inoue
- T Kurze
- T Yoshii
- T Yoshizu
- TC Kriss
- TG Skoulis
- TH Robbins
- TJ Krizek
- TM Nassif
- TM Tsai
- TM Whitney
- V Gomel
- V Gomel
- W Schubert
- W Walz
- WA Morrison
- WA Morrison
- WG El-Barrany
- WH Howell
- WM Lougheed
- WP Coomey 3rd
- Y Akasaka
- Y Hirase
- Y Hirase
- Y Ikuta
- Y Ikuta
- Y Onji
- Y Onji
- Y Ueba
- Y Yabe
- Y Yamano
- YD Gu
- ZM Arnez
- ZW Chen
- ZW Chen
- ZW Chen
- ZW Chen
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2003
- Field of study
Prise de décision dans la famille: Une bibliographie sélective (1980–1990)
- Author
- Ajith Kumar
- Alan Acock C.
- Alan Acock C.
- Alan Sillars
- Alice Courtney
- Alladi Venkatesh
- Alladi Venkatesh
- Alladi Venkatesh
- Allan Carlson C.
- Alvin Burns C.
- Alvin Burns C.
- Alvin Burns C.
- Alvin Burns C.
- Alvin Burns C.
- Alvin Burns C.
- Amrya Grossbard-Shechtman
- Andrée Michel
- Ann Foster C.
- Ann Oakley
- Anne Fitzpatrick Mary
- Anne Locksley
- Anne Pebley R.
- Arthur Norton J.
- Arthur Wolf P.
- Ascoli U.
- Aurèle Saint-Yves
- Backett K.
- Barbara Redman J.
- Barkas J. L.
- Barrett M.
- Barrie Thorne
- Ben Enis M.
- Benny Rigaux-Bricmont
- Benny Rigaux-Bricmont
- Benny Rigaux-Bricmont
- Benny Rigaux-Bricmont
- Berk S.
- Bernadette Gray-Little
- Bernard Jaworski J.
- Bescher-Donnelly L.
- Bickley Townsend
- Boisard P.
- Bonfield E. H.
- Bonnie Reece B.
- Brad Edmondson
- Brian Foster L.
- Carl Degler N.
- Carlson B. E.
- Carmel Chiswick U.
- Carol Tittle K.
- Carolyn Cohen B.
- Carrie Tuhy
- Caryl Rivers
- Catherine Nichols M.
- Chabaud D.
- Chankon Kim
- Chankon Kim
- Charles Atkin K.
- Charles Madden S.
- Charles Schaninger M.
- Charles Schaninger M.
- Charles Schaninger M.
- Charles Schaninger M.
- Charles Schaninger M.
- Charles Schaninger M.
- Charles Schaninger M.
- Charles Willie V.
- Cherlin A.
- Cherlin A.
- Cheryl Russel
- Chris Allen T.
- Chris Allen T.
- Christian Buss W.
- Christian Buss W.
- Chumlea W. C.
- Clair Vickery
- Daisy Quarm
- Dandurand R. B.
- Daniel Seymour
- Daniel Seymour
- Darroch D. B.
- David Bloom E.
- David Bloom E.
- David Bloom E.
- David Brinberg
- David Brinberg
- David Brinberg
- David Buss M.
- David Fritzsche
- David Jorgenson E.
- David Kenny A.
- David Reiss
- Deborah Heisley D.
- Deborah Roedder L.
- Del Boca Fiances K.
- Dennis Rosen L.
- Dickson P. R.
- Don Bellante
- Donald Hempel J.
- Donna Brogan
- Doris Walsh
- Doris Walsh
- Douglass Hawes K.
- Dwayne Ball
- Eleanor Macklin D.
- Elizabeth Maret
- Elizabeth Maret
- Elizabeth Moore-Shay
- Elizabeth Moore-Shay
- Elizabeth Thomson
- Elizabeth Thomson
- Ellen Foxman
- Ellen Foxman R.
- Ellen Foxman R.
- Ellen Foxman R.
- Ellen Hock
- Ellis R.
- Eric Arnould J.
- Erich Kirchler
- Fabian Linden
- Feldman L. B.
- Fran Pepitone-Rockwell
- Francine Blau D.
- Frank Stafford P.
- Fred Selnes
- Frederick Derrick W.
- Frederick Klein C.
- Gary Becker S.
- George Moschis P.
- George Moschis P.
- George Moschis P.
- George Moschis P.
- George Moschis P.
- George Moschis P.
- Giovanna Imperia
- Glenna Spitze
- Glenna Spitze
- Gordon Bivens E.
- Gordon Streib F.
- Graham Spanier B.
- Graham Spanier B.
- Graham Staines L.
- Grashof J. F.
- Gupta S.
- Harold Berenson
- Harry Davis L.
- Helen Lopata Z.
- Hila Kahne
- Howard Hayghe
- Howard Hayghe
- Howard Hayghe V.
- Irving Tallman J.
- Jacob Hornik
- Jacob Hornik
- Jacob Hornik
- Jagdish Sheth N.
- James Armentrout A.
- James Blaylock R.
- James Jaccard
- James Leigh H.
- James Leigh H.
- James Morgan N.
- James Morgan N.
- James Shanteau
- James Weed A.
- Janet Boekmeier
- Janet Hunt C.
- Janet Hunt C.
- Janet Hunt C.
- Janet Wagner
- Jay Cherlow R.
- Jean Atkinson
- Jeffrey Rosenfeld
- Jo Bane Mary
- Joan Aldous
- Joann Vanek
- Joel Moses
- Joel Rudd
- Johan Arndt
- John Burnett J.
- John Ivancevich M.
- John Menefee A.
- John Robinson P.
- John Scanzoni
- John Scanzoni
- John Scanzoni
- John Scanzoni
- John Tydeman
- Jolibert A. J. P.
- Jon Freiden B.
- Jonathan Guttman
- Joseph Bellizzi A.
- Joseph Hu
- Joseph Murphy R.
- Joseph Pleck H.
- Joseph Pleck H.
- Joseph Pleck H.
- Joseph Pleck H.
- Joy Teachman D.
- Judith Langer
- Julia Bristor M.
- Kamas Yokum J.
- Karen Bunch L.
- Karen Fox D.
- Karen Fox F. A.
- Karen Goebel P.
- Karin Ekström M.
- Kathryn Britney
- Keith Bryant W.
- Kellerhals J.
- Kenneth Bahn D.
- Kenneth Friend E.
- Kertzer D. I.
- Kim Corfman P.
- Kim Corfman P.
- Kim Corfman P.
- Kjell Gronhaug
- Kristina Cooper
- Lakshman Krishnamurthi
- Lakshman Krishnamurthi
- Laura Lein
- Laura Lein
- Laurence Feldman P.
- Lawrence Crosby A.
- Lawrence Crosby A.
- Lawrence Crosby A.
- Lawrence Wortzel H.
- Lerner R. M.
- Les Carlson
- Leslie Isler
- Lewis C.
- Linda Beckman J.
- Lisa Alaniz P.
- Lois Blumberg Rhoda
- Lou Roberts Mary
- Lou Roberts Mary
- Lou Roberts Mary
- Lou Roberts Mary
- Lou Roberts Mary
- Louis Wagner C.
- Louise Heslop A.
- Lynn Schnurnberger
- Mann Smith Leslie
- Marforie Lueck
- Margaret Davis R.
- Margaret Nelson C.
- Marianne Ferber A.
- Marianne Ferber A.
- Marilyn Kourilsky
- Marilyn Manser
- Mark Rank R.
- Mark Rosenzweig
- Marsh L. C.
- Martha Hill S.
- Marx Ferre Nyra
- Mary Fox F.
- Mary Kriewall
- Matthew Melko
- Maximiliane Szinovacz
- Maximiliane Szinovacz
- McCall Suzanne H.
- McDevitt Thomas M.
- McDonald G. W.
- McLaughlin Edward W.
- McNeal James U.
- Melody Douglas-Tate
- Michael Geeken
- Michael Heffring P.
- Michael Mayo C.
- Michael Menasco B.
- Michael Reilly D.
- Michael Ryan J.
- Michael Troutman C.
- Michel Legrand
- Mohamed Abdel-Ghany
- Morris Holbrook B.
- Morris Holbrook B.
- Morval M. V. G.
- Myra Strober H.
- Nicholas Vitalari
- Norman Anderson H.
- O'Conner P. J.
- Orjan Hultaker E.
- Otto Pollak
- Pamela Monroe A.
- Pat Keith M.
- Patricia Sorce
- Patrick Murphy E.
- Patriya Tansuhaj S.
- Paul Glick C.
- Peter Laslett
- Peter Stein
- Peter Wright
- Philip Hendrix E.
- Philip Hendrix E.
- Philip Hendrix E.
- Phillip Hendrix E.
- Pierre Filiatrault
- Piotrkowski C. S.
- Poloma M. M.
- Raj Foster Irene
- Ralph Jackson W.
- Rebecca Holman
- Rebecca Holman H.
- Rebecca Holman H.
- Rena Bartos
- Reuben Hill
- Rhona Rapoport
- Riblett Wilkie Jane
- Richard Olshavsky W.
- Richard Udry J.
- Richard Wilk R.
- Richard Wilk R.
- Robert Ferber
- Robert Graham J.
- Robert Green T.
- Robert Kelly F.
- Robert Netting McC.
- Ronald Michman D.
- Rosann Spiro L.
- Roy Beach Lee
- Russell Belk W.
- Ruth Katz
- Sandra Hofferth L.
- Sanford Grossbart
- Sanford Grossbart
- Schlesinger R.
- Scott Poole Marshall
- Scott Ward
- Scott Ward
- Scott Ward
- Scott Ward
- Sgritta G. B.
- Sharda B. D.
- Sharon Nickols Y.
- Sharon Nickols Y.
- Shelley Coverman
- Shelley Coverman
- Shreekant Joag G.
- Sidney Bennett C.
- Simpson I. H.
- Stephanie Shipp
- Steve Rawlings W.
- Steven Mintz
- Stilley Hopper Joanne
- Susan Douglas P.
- Susan Heckler E.
- Susan Shank E.
- Suzanne Bianchi M.
- Suzanne Model
- Tamara Hareven
- Thomas Barry E.
- Thomas Crawford J.
- Thomas Espenshade J.
- Thomas Espenshade J.
- Thomas Holman B.
- Thomas Juster F.
- Thomas Juster F.
- Thomas O'Guinn C.
- Thomas Whipple
- Toni Falbo
- Umesh U. N.
- US Bureau of the Census
- US Bureau of the Census
- US Bureau of the Census
- US Bureau of the Census
- Valarie Zeithaml A.
- Ved Prakash
- Wesley Becker C.
- White Stephan Cookie
- William Darley F.
- William Dunn
- William Dunn
- William Gauger H.
- William Quails J.
- William Quails J.
- William Quails J.
- William Quails J.
- William Weeks A.
- Yung-Ping Chen
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study