<i>LTA4H</i> genotypes, dexamethasone and survival in bacterial meningitis patients.

<p>Kaplan-Meier estimates of survival among BM patients stratified by their rs17525495 genotype in, (A) all BM patients (bacterially confirmed and probable), (B) all BM patients who received placebo, (C) all BM patients who received dexamethasone (D) definite BM patients (bacterially confirmed), (E) definite BM patients who received placebo and (F) definite BM patients who received dexamethasone. Solid line denotes TT, dash line denotes CT, and dot-dash line denotes CC genotype group. Comparisons of survival between genotypes were based on Cox regression models adjusted for the randomized treatment group</p

rs17525495 is associated with susceptibility to bacterial meningitis.

<p>^<i>a</i>frequency</p><p>^<i>b</i>cytosine</p><p>^<i>c</i>thymine</p><p>^<i>d</i>additive model</p><p>^<i>e</i>odds ratio (95% confidence interval)</p><p>^<i>f</i>general model; a genotypic model where one genotype group (e.g. CC group) is baseline</p><p>^<i>g</i>estimates of odds for general model, comparing baseline (CC) to CT</p><p>^<i>h</i>estimates of odds for general model comparing baseline (CC) to TT</p><p>^<i>i</i>recessive model</p><p>^<i>j</i>Hardy Weinberg Equilibrium</p><p>^<i>k</i>definite. NB: data for dominant and heterozygote advantage model were not significant and are not shown here.</p><p>rs17525495 is associated with susceptibility to bacterial meningitis.</p