Critical Review : Pengaruh Antosianin Terhadap Kadar Glukosa Darah Pada Hewan Coba Tikus Diabetes Melitus Tipe Ii

Type 2 diabetes mellitus is a disease characterized by hyperglycemia and to prevent and overcome namely by regulating diet by consuming foods that have antioxidant effects such as anthocyanins. This study aimed to review several articles on the effect of anthocyanins on blood glucose levels in experimental animals with type 2 DM rats. . Articles were searched using Google Scholar with terms indexed by Sinta 1–4 and indexed by Schimagojr Q1–Q4. The keywords used were “antidiabetic”, “anthocyanin”, “blood glucose level”, “diabetes mellitus”, “DM rats”, “hyperglycemic rats”. The inclusion criteria were DM or hyperglycemic rat subjects, examining blood glucose levels, sources of anthocyanins from foodstuffs, types of experimental research and articles within the last 10 years. Exclusion criteria were inappropriate articles, non-journals, not fully accessible, not indexed by sinta 1–4 or Q1–Q4, subjects were not rats with diabetes or hyperglycemia, anthocyanins were not from food, and there was no checking blood glucose levels. The results of a critical review on 10 articles showed that anthocyanins had a significant effect in reducing blood glucose levels in hyperglycemic rats or diabetes mellitus rats (p = 0,000), and the best results were anthocyanins from black rice bran with the results of measuring glucose levels after treatment. of 131,33 mg/dL. The percentage decrease in blood glucose levels in 9 articles ranged from 20,37% - 71,32%. Anthocyanins have an effect on decreasing blood glucose levels in experimental animals with type 2 diabetes mellitus rat