308 research outputs found

    Space Tools for Servicing, Repairing, and Maintaining Spacecraft

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    Just like mechanics and technicians on Earth, astronauts use a variety of manual and portable power tools in space to repair, service, and maintain spacecraft, like the Space Shuttle and the International Space Station (ISS), and other satellites, like the Hubble Space Telescope (HST). Space tools are divided into two main operating categories: Intravehicular Activity (IVA) tools and Extravehicular Activity (EVA) tools. N A tools are used by astronauts inside the pressurized habitable compartments of a spacecraft for routine maintenance, repair, and unexpected tasks. EVA tools are used by space-suited astronauts outside of their pressurized spacecraft in the vacuum of space

    Constellation Program Design Challenges as Opportunities for Educational Outreach- Lessons Learned

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    The Texas Space Grant Consortium (TSGC) and the NASA Exploration Systems Mission Directorate (ESMD) Education Office both have programs that present design challenges for university senior design classes that offer great opportunities for educational outreach and workforce development. These design challenges have been identified by NASA engineers and scientists as actual design problems faced by the Constellation Program in its exploration missions and architecture. Student teams formed in their senior design class select and then work on a design challenge for one or two semesters. The senior design class follows the requirements set by their university, but it must also comply with the Accreditation Board for Engineering and Technology (ABET) in order to meet the class academic requirements. Based on a one year fellowship at a TSGC university under the NASA Administrator's Fellowship Program (NAFP) and several years of experience, lessons learned are presented on the NASA Design Challenge Program

    Crew Clothing Odor Absorbing Stowage Container

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    Walking to Olympus: An EVA Chronology

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    Spacewalkers enjoy a view of Earth once reserved for Apollo, Zeus, and other denizens of Mt. Olympus. During humanity's first extravehicular activity (EVA), Alexei Leonov floated above Gibraltar, the rock ancient seafarers saw as the gateway to the great unknown Atlantic. The symbolism was clear, Leonov stepped past a new Gibraltar when he stepped into space. More than 32 years and 154 EVAs later, Jerry Linenger conducted an EVA with Vladimir Tsibliyev as part of International Space Station Phase 1. They floated together above Gibraltar. Today the symbolism has new meaning: humanity is starting to think of stepping out of Earth orbit, space travel's new Gibraltar, and perhaps obtaining a new olympian view, a close-up look at Olympus Mons on Mars. Walking to Olympus: An EVA Chronology chronicles the 154 EVAs conducted from March 1965 to April 1997. It is intended to make clear the crucial role played by EVA in the history of spaceflight, as well as to chronicle the large body of EVA "lessons learned." Russia and the U.S. define EVA differently. Russian cosmonauts are said to perform EVA any time they are in vacuum in a space suit. A U.S. astronaut must have at least his head outside his spacecraft before he is said to perform an EVA. The difference is based in differing spacecraft design philoso- phies. Russian and Soviet spacecraft have always had a specialized airlock through which the EVA cosmonaut egressed, leaving the main habitable volume of the spacecraft pressurized. The U.S. Gemini and Apollo vehicles, on the other hand, depressurized their entire habitable volume for egress. In this document, we apply the Russian definition to Russian EVAS, and the U.S. definition to U.S. EVAS. Thus, for example, Gemini 4 Command Pilot James McDivitt does not share the honor of being first American spacewalker with Ed White, even though he was suited and in vacuum when White stepped out into space. Non-EVA spaceflights are listed in the chronology to provide context and to display the large num- ber of flights in which EVA played a role. This approach also makes apparent significant EVA gaps, for example, the U.S. gap between 1985 and 1991 following the Challenger accident. This NASA History Monograph is an edited extract from an extensive EVA Chronology and Reference Book being produced by the EVA Project Office, NASA Johnson Space Center, Houston, Texas. The larger work will be published as part of the NASA Formal Series in 1998. The authors gratefully acknowledge the assistance rendered by Max Ary, Ashot Bakunts, Gert-Jan Bartelds, Frank Cepollina, Andrew Chaikin, Phillip Clark, Richard Fullerton, Steven Glenn, Linda Godwin, Jennifer Green, Greg Harris, Clifford Hess, Jeffrey Hoffman, David Homan, Steven Hopkins, Nicholas Johnson, Eric Jones, Neville Kidger, Joseph Kosmo, Alexei Lebedev, Mark Lee, James LeBlanc, Dmitri Leshchenskii, Jerry Linenger, Igor Lissov, James McBarron, Clay McCullough, Joseph McMann, Story Musgrave, Dennis Newkirk, James Oberg, Joel Powell, Lee Saegesser, Andy Salmon, Glen Swanson, Joseph Tatarewicz, Kathy Thornton, Chris Vandenberg, Charles Vick, Bert Vis, David Woods, Mike Wright, John Young, and Keith Zimmerman. Special thanks to Laurie Buchanan, John Charles, Janet Kovacevich, Joseph Loftus, Sue McDonald, Martha Munies, Colleen Rapp, and Jerry Ross. Any errors remain the responsibility of the authors

    Efficacy of Wrist/Palm Warming as an EVA Countermeasure to Maintain Finger Comfort in Cold Conditions During EVA

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    This study explored the effectiveness of local wrist/palm warming as a potential countermeasure for providing finger comfort during extended duration EVA. Methods: Six subjects (5 males and 1 female) were evaluated in a sagitally divided liquid cooling/warming garment (LCWG) with modified liquid cooling/warming (LCW) gloves in three different experimental conditions. Condition 1: Stage 1- no LCWG; chamber adaptation with LCW glove inlet water temperature 33 C; Stage 2-LCW glove inlet water temperature cooled to 8 C; Stage 3-LCW glove inlet water temperature warmed to 45 C; Condition 2: Stage1-LCWG and LCW glove inlet water temperature 33 C; Stage 2-LCWG inlet temperature cooled to 31 C, LCW gloves, 8 C; Stage 3-LCWG inlet water temperature remains at 31 C, LCW glove inlet water temperature warmed to 45 C; Condition 3: Stage l -LCWG and LCW gloves 33 C; Stage 2-LCWG inlet water temperature cooled to 28 C, LCW gloves, 8 C; Stage 3-LCWG remains at 28 C, LCW glove water temperature warmed to 45 C. Results: Wrist/palm area warming significantly increased finger temperature (Tfing) and blood perfusion in Stage 3 compared to Stage 2. The LCW gloves were most effective in increasing Stage 3 Tfing in Condition 1; and in increasing blood perfusion in Conditions 1 and 2 compared to Condition 3. Ratings of subjective perception of heat in the hand and overall body heat were higher at Stage 3 than Stage 2, with no significant differences across Conditions. Conclusions: Local wrist/palm warming was effective in increasing blood circulation to the distal extremities, suggesting the potential usefulness of this technique for increasing astronaut thermal comfort during EVA while decreasing power requirements. The LCW gloves were effective in heating the highly cooled fingers when the overall body was in a mild heat deficit

    Fabric circuits and method of manufacturing fabric circuits

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    A flexible, fabric-based circuit comprises a non-conductive flexible layer of fabric and a conductive flexible layer of fabric adjacent thereto. A non-conductive thread, an adhesive, and/or other means may be used for attaching the conductive layer to the non-conductive layer. In some embodiments, the layers are attached by a computer-driven embroidery machine at pre-determined portions or locations in accordance with a pre-determined attachment layout before automated cutting. In some other embodiments, an automated milling machine or a computer-driven laser using a pre-designed circuit trace as a template cuts the conductive layer so as to separate an undesired portion of the conductive layer from a desired portion of the conductive layer. Additional layers of conductive fabric may be attached in some embodiments to form a multi-layer construct

    Making Complex Electrically Conductive Patterns on Cloth

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    A method for automated fabrication of flexible, electrically conductive patterns on cloth substrates has been demonstrated. Products developed using this method, or related prior methods, are instances of a technology known as 'e-textiles,' in which electrically conductive patterns ar formed in, and on, textiles. For many applications, including high-speed digital circuits, antennas, and radio frequency (RF) circuits, an e-textile method should be capable of providing high surface conductivity, tight tolerances for control of characteristic impedances, and geometrically complex conductive patterns. Unlike prior methods, the present method satisfies all three of these criteria. Typical patterns can include such circuit structures as RF transmission lines, antennas, filters, and other conductive patterns equivalent to those of conventional printed circuits. The present method overcomes the limitations of the prior methods for forming the equivalent of printed circuits on cloth. A typical fabrication process according to the present method involves selecting the appropriate conductive and non-conductive fabric layers to build the e-textile circuit. The present method uses commercially available woven conductive cloth with established surface conductivity specifications. Dielectric constant, loss tangent, and thickness are some of the parameters to be considered for the non-conductive fabric layers. The circuit design of the conductive woven fabric is secured onto a non-conductive fabric layer using sewing, embroidery, and/or adhesive means. The portion of the conductive fabric that is not part of the circuit is next cut from the desired circuit using an automated machine such as a printed-circuit-board milling machine or a laser cutting machine. Fiducials can be used to align the circuit and the cutting machine. Multilayer circuits can be built starting with the inner layer and using conductive thread to make electrical connections between layers

    Portraying the nature of corruption: Using an explorative case-study design

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    What is the nature of corruption in Western democracies? To answer this research question, the authors study 10 Dutch corruption cases in depth, looking at confidential criminal files. The cases allow them to sketch a general profile of a corruption case. The authors offer nine propositions to portray the nature of corruption. They conclude that corruption usually takes place within enduring relationships, that the process of becoming corrupt can be characterized as a slippery slope, and that important motives for corruption, aside from material gain, include friendship or love, status, and the desire to impress others. The explorative multiple case study methodology helps to expand our understanding of the way in which officials become corrupt. Β© 2008 The American Society for Public Administration

    Allelic replacement of the streptococcal cysteine protease SpeB in a Ξ”srv mutant background restores biofilm formation

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    <p>Abstract</p> <p>Background</p> <p>Group A <it>Streptococcus </it>(GAS) is a Gram-positive human pathogen that is capable of causing a wide spectrum of human disease. Thus, the organism has evolved to colonize a number of physiologically distinct host sites. One such mechanism to aid colonization is the formation of a biofilm. We have recently shown that inactivation of the streptococcal regulator of virulence (Srv), results in a mutant strain exhibiting a significant reduction in biofilm formation. Unlike the parental strain (MGAS5005), the streptococcal cysteine protease (SpeB) is constitutively produced by the <it>srv </it>mutant (MGAS5005Ξ”<it>srv</it>) suggesting Srv contributes to the control of SpeB production. Given that SpeB is a potent protease, we hypothesized that the biofilm deficient phenotype of the <it>srv </it>mutant was due to the constitutive production of SpeB. In support of this hypothesis, we have previously demonstrated that treating cultures with E64, a commercially available chemical inhibitor of cysteine proteases, restored the ability of MGAS5005Ξ”<it>srv </it>to form biofilms. Still, it was unclear if the loss of biofilm formation by MGAS5005Ξ”<it>srv </it>was due only to the constitutive production of SpeB or to other changes inherent in the <it>srv </it>mutant strain. To address this question, we constructed a Ξ”<it>srv</it>Ξ”<it>speB </it>double mutant through allelic replacement (MGAS5005Ξ”<it>srv</it>Ξ”<it>speB</it>) and tested its ability to form biofilms <it>in vitro</it>.</p> <p>Findings</p> <p>Allelic replacement of <it>speB </it>in the <it>srv </it>mutant background restored the ability of this strain to form biofilms under static and continuous flow conditions. Furthermore, addition of purified SpeB to actively growing wild-type cultures significantly inhibited biofilm formation.</p> <p>Conclusions</p> <p>The constitutive production of SpeB by the <it>srv </it>mutant strain is responsible for the significant reduction of biofilm formation previously observed. The double mutant supports a model by which Srv contributes to biofilm formation and/or dispersal through regulation of <it>speB</it>/SpeB.</p

    Dispersal of Group A Streptococcal Biofilms by the Cysteine Protease SpeB Leads to Increased Disease Severity in a Murine Model

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    Group A Streptococcus (GAS) is a Gram-positive human pathogen best known for causing pharyngeal and mild skin infections. However, in the 1980's there was an increase in severe GAS infections including cellulitis and deeper tissue infections like necrotizing fasciitis. Particularly striking about this elevation in the incidence of severe disease was that those most often affected were previously healthy individuals. Several groups have shown that changes in gene content or regulation, as with proteases, may contribute to severe disease; yet strains harboring these proteases continue to cause mild disease as well. We and others have shown that group A streptococci (MGAS5005) reside within biofilms both in vitro and in vivo. That is to say that the organism colonizes a host surface and forms a 3-dimensional community encased in a protective matrix of extracellular protein, DNA and polysaccharide(s). However, the mechanism of assembly or dispersal of these structures is unclear, as is the relationship of these structures to disease outcome. Recently we reported that allelic replacement of the streptococcal regulator srv resulted in constitutive production of the streptococcal cysteine protease SpeB. We further showed that the constitutive production of SpeB significantly decreased MGAS5005Ξ”srv biofilm formation in vitro. Here we show that mice infected with MGAS5005Ξ”srv had significantly larger lesion development than wild-type infected animals. Histopathology, Gram-staining and immunofluorescence link the increased lesion development with lack of disease containment, lack of biofilm formation, and readily detectable levels of SpeB in the tissue. Treatment of MGAS5005Ξ”srv infected lesions with a chemical inhibitor of SpeB significantly reduced lesion formation and disease spread to wild-type levels. Furthermore, inactivation of speB in the MGAS5005Ξ”srv background reduced lesion formation to wild-type levels. Taken together, these data suggest a mechanism by which GAS disease may transition from mild to severe through the Srv mediated dispersal of GAS biofilms
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