TÀI NGUYÊN VỊ THẾ ĐẢO CỒN CỎ

Being a basaltic volcano, Con Co island is an isometric hill 2.3 km2 wide and 63 m high, located far 24 km from the mainland, and guards the entrance to the Gulf of Tonkin. It is isolated, but unique in location, and relatively closed to mainland. Despite its small size, the characteristics of morphology and spatial structures, geological composition, area, height, ecological landscape, dynamics and stability of the island... create great values of geo-natural position resources and favorable environment for island residents. Regarding geo - economic position resources, the island is a district under the Quang Tri province, a priority location for development of the country’s marine and island economy, and the economic centre at the entrance of the Gulf of Tonkin. This is also a convenient site for the development of marine economic sectors such as fishery, natural conservation, services - tourism and some others. In terms of geo-political position resources, the island has tremendous advantages for the sovereignty, sovereign rights and national interests at sea. As an outpost at the highly sensitive geo-political area, the Con Co island has the great value of defense, as a solid military base in the entrance of the Gulf of Tonkin and the most important link in the line of defense from coastal islands in the North Centre. It possesses many valuable cultural heritages, especially the heroic relics during the war against the US.Đảo Cồn Cỏ nguồn gốc núi lửa bazan, dạng đồi đẳng thước rộng 2,3 km2, cao 63 m, nằm cách xa bờ 24 km. Đảo có vị trí lẻ loi ở cửa vịnh Bắc Bộ và khá gần bờ Việt Nam. Mặc dù diện tích đảo nhỏ, nhưng các đặc điểm về hình thể và cấu trúc không gian, cấu tạo địa chất; diện tích, độ cao và cảnh quan sinh thái; động lực và tính ổn định... đã tạo ra giá trị lớn cho đảo về tài nguyên địa - tự nhiên và môi trường sinh cư thuận lợi cho các loài sinh vật và con người. Về giá trị vị thế địa - kinh tế, Cồn Cỏ thuộc đơn vị hành chính cấp huyện thuộc tỉnh Quảng Trị, là vị trí ưu tiên đối với phát triển kinh tế biển - đảo của đất nước; là vị trí trung tâm của không gian kinh tế khu cửa vịnh Bắc Bộ. Đây là một địa bàn thuận lợi cho phát triển các lĩnh vực kinh tế biển như thủy sản, bảo tồn biển, dịch vụ - du lịch cùng với các loại hình dịch vụ khác. Về giá trị vị thế địa - chính trị, đảo Cồn Cỏ có giá trị to lớn đối với việc bảo vệ các quyền và lợi ích quốc gia của Việt Nam trên biển. Là đảo tiền tiêu nằm trong vùng địa - chính trị nhạy cảm cao, đảo có giá trị lớn về phòng thủ, là một cứ điểm quân sự vững chắc ở vùng cửa vịnh Bắc Bộ và mắt xích quan trọng nhất trong phòng tuyến các đảo ven bờ Bắc Trung Bộ. Cồn Cỏ có các giá trị di sản văn hoá biển đảo, đặc biệt là những chiến tích anh hùng trong thời chiến tranh chống Mỹ

Acceptance patterns and decision-making for human papillomavirus vaccination among parents in Vietnam: an in-depth qualitative study post-vaccination

BACKGROUND: The GAVI Alliance’s decision in late 2011 to invite developing countries to apply for funding for human papillomavirus (HPV) vaccine introduction underscores the importance of understanding levels of HPV vaccine acceptance in developing country settings. In this paper, we present findings from qualitative research on parents’ rationales for vaccinating or not vaccinating their daughters (vaccine acceptance) and their decision-making process in the context of an HPV vaccination demonstration project in Vietnam (2008–2009). METHODS: We designed a descriptive qualitative study of HPV vaccine acceptability among parents of girls eligible for vaccination in four districts of two provinces in Vietnam(a). The study was implemented after each of two years of vaccinations was completed. In total, 133 parents participated in 16 focus group discussions and 27 semi-structured interviews. RESULTS: Focus group discussions and in-depth interviews with parents of girls vaccinated revealed that they were generally very supportive of immunization for disease prevention and of vaccinating girls against HPV. The involvement of the National Expanded Program of Immunization in the demonstration project lent credibility to the HPV vaccine, contributing to high levels of acceptance. For parents who declined participation, concerns about side effects, the possibility that the vaccine was experimental, and the possible impact of the vaccine on future fertility rose to the surface. In terms of the decision-making process, many parents exhibited ‘active decision-making,’ reaching out to friends, family, and opinion leaders for guidance prior to making their decision. CONCLUSION: Vietnam’s HPV vaccination experience speaks to the importance of close collaboration with the government to make the most of high levels of trust, and to reduce suspicions about new vaccines that may arise in the context of vaccine introduction in developing country settings

Differentiation Effect of Two Alkaloid Fractions from Vietnamese Lycopodiaceae on Mouse Neural Stem Cells

Various Lycopodium alkaloids have been studied for their various biological activities including anti-inflammatory, antioxidant, immunomodulatory, and neuroprotective activities. Moreover, these alkaloid compounds have high potential in the treatment of neuron degenerative disease. This study has been carried out to test the effect of Huperzia serrata (Thunb.) Trevis, and Lycopodium clavatum L alkaloid fractions on the mouse neural stem cells (NSCs). Firstly, the alkaloid fractions were used to verify its toxicity on NSCs. The multiple concentrations of alkaloid fractions from H. serrata (0.044; 0.088; 0.175; 0.35; 0.7; 1.4 mg/ml) and L. clavatum (0.031; 0.063; 0.125; 0.25; 0.50; 1.0; 2.0 mg/ml) have been used for the treatment of NSCs at period of 48h incubation. Results of the study suggested that the IC50 value of H. serrata and L. clavatum was 0.56 mg/ml and 0.50 mg/ml, respectively. Then, the NSCs were differentiated in the presence of 5 and 10 µg/ml of alkaloid fraction from H. serrata; 0.625 and 1.25 µg/ml of alkaloid fraction from L. clavatum for 6 days. Here, we observed the primary NSCs treated with alkaloid fraction extract from H. serrata showed the increased gene expression level of early neuron TUBB3 and neuron-specific cytoskeleton MAP2. On the other hand, the L. clavatum alkaloid fraction increased the expression of neural stem cell marker genes (Nestin and PAX6) and decreased neuron marker genes. In conclusion, these results established that alkaloid fraction from H. serrata promoted differentiation of the mouse NSCs to neuron cells, and L. clavatum extract had a capacity for stemness maintenance