New low-density-parity-check decoding approach based on the hard and soft decisions algorithms

It is proved that hard decision algorithms are more appropriate than a soft decision for low-density parity-check (LDPC) decoding since they are less complex at the decoding level. On the other hand, it is notable that the soft decision algorithm outperforms the hard decision one in terms of the bit error rate (BER) gap. In order to minimize the BER and the gap between these two families of LDPC codes, a new LDPC decoding algorithm is suggested in this paper, which is based on both the normalized min-sum (NMS) and modified-weighted bit-flipping (MWBF). The proposed algorithm is named normalized min sum- modified weighted bit flipping (NMSMWBF). The MWBF is executed after the NMS algorithm. The simulations show that our algorithm outperforms the NMS in terms of BER at 10-8 over the additive white gaussian noise (AWGN) channel by 0.25 dB. Furthermore, the proposed NMSMWBF and the NMS are both at the same level of decoding difficulty

Recessive mutation in tetraspanin CD151 causes Kindler syndrome-like epidermolysis bullosa with multi-systemic manifestations including nephropathy

Epidermolysis bullosa (EB) is caused by mutations in as many as 19 distinct genes. We have developed a next-generation sequencing (NGS) panel targeting genes known to be mutated in skin fragility disorders, including tetraspanin CD151 expressed in keratinocytes at the dermal-epidermal junction. The NGS panel was applied to a cohort of 92 consanguineous families of unknown subtype of EB. In one family, a homozygous donor splice site mutation in CD151 (NM_139029; c.351 + 2T > C) at the exon 5/intron 5 border was identified, and RT-PCR and whole transcriptome analysis by RNA-seq confirmed deletion of the entire exon 5 encoding 25 amino acids. Immunofluorescence of proband's skin and Western blot of skin proteins with a monoclonal antibody revealed complete absence of CD151. Transmission electron microscopy showed intracellular disruption and cell-cell dysadhesion of keratinocytes in the lower epidermis. Clinical examination of the 33-year old proband, initially diagnosed as Kindler syndrome, revealed widespread blistering, particularly on pretibial areas, poikiloderma, nail dystrophy, loss of teeth, early onset alopecia, and esophageal webbing and strictures. The patient also had history of nephropathy with proteinuria. Collectively, the results suggest that biallelic loss-of-function mutations in CD151 underlie an autosomal recessive mechano-bullous disease with systemic features. Thus, CD151 should be considered as the 20th causative, EB-associated gene

Nouvelles revendications féministes et médias numériques. Contournement des interdits sociaux et religieux en Tunisie et Maroc

National audienc

Évolution des modalités d'expression et d'action féministes dans les médias numériques au Maroc et en Tunisie.

International audienc

New Feminist Claims and Digital Media: Circumvention of Social and Religious Prohibitions in Tunisia and Morocco

This paper deals with the question of Tunisian and Moroccan women presence on social networks.An analysis of how they grab these digital tools to make their new right claims visible.Our methodology and our questions arise essentially from the ethnography of electronic communication and semio-pragmatics.Our objective here is to observe and describe devices, uses and actors involved in these new online mobilization and activismmedia for women benefit in Tunisia and Morocco. Two web corpuses are analyzed.The first corpus comes from a regular watch on Facebook accounts of associations, activists and ordinary net users in Tunisia.The second one is made up of 12 episodes of “Marokkiates” web series broadcast on Facebook and Youtube in 2017-2018.These corpuses have led to a contrastive study of new digital forms of mobilization, circumvention of social or religious prohibitions,activism for women new rights detailing as well the current feminism uses in the two north Africa countries