Exploratory predictive and prognostic factors in advanced breast cancer treated with metronomic chemotherapy. Anticancer Drugs

Primary adenocarcinomas of the gastrointestinal tract showing a diffuse thyroid transcription factor-1 (TTF-1)-positive immunostaining are extremely uncommon and this finding in the biopsy specimen could yield to misleading diagnosis of a metastatic lung tumor. We report the clinical and pathological features of 2 cases, occurring in a 62-year-old woman and in a 66-year-old man. The first one is a gastric adenocarcinoma with liver metastasis; the other one is a gallbladder adenocarcinoma discovered during the screening for the colorectal cancer. Both the neoplasms showed a diffuse TTF-1 positivity and both the patients did not have any evidence of lung cancer. Neither a gastric adenocrcinoma with diffuse TTF-1 expression nor a TTF-1-positive gallbladder adenocarcinoma has been described befor

Psychometric properties of the Brazilian Intolerance of Uncertainty Scale – Short Version (IUS-12)

Understanding how people forget is one of the fundamental goals of the science of memory. Recent studies indicate that humans can voluntarily regulate awareness of unwanted memories by stopping the retrieval process that would ordinarily bring past experience into awareness. Event-related potential (ERP) research on memory retrieval reveals that electrophysiological effects with specific timing and scalp topography serve as markers of memory processes. This systematic review examines the literature regarding EEG alterations in memory suppression, highlighting their results on electrophysiological indicators. A systematic review from January 2007 to November 2017 was conducted using PubMed, Embase and ScienceDirect databases. As results, 12 studies were eligible for inclusion. Quantitative EEG can be a objective tool for studying the mechanisms involved in memory suppression. There is evidence that a parietal positivity around 400-800ms after cue presentation is an ERP marker of conscious recollection during memory retrieval and a larger N2 deflection during retrieval suppression predicted greater suppression-induced forgetting