Prevalence of Asymptomatic Abdominal Aortic Aneurysm in Patients with Carotid Stenosis

The aim of this study was to demonstrate the prevalence of abdominal aortic aneurysm in patients with carotid disease and to analyse the influence of cardiovascular risk factors for abdominal aortic aneurysm. Methods: Ultrasound for abdominal aortic aneurysm was performed in 200 patients (112 men and 88 women, mean age 65.72±7.71 years) with known carotid disease. The primary cardiovascular risk factors (age, sex, hypertension, diabetes, dyslipidaemia and smoking) were analysed. Results: We found that 15.5% of patients with carotid stenosis also had abdominal aortic aneurysm. The prevalence of abdominal aortic aneurysm was higher in men (22.23%) than in women (6.81%). There was no correlation between the severity of carotid disease and the diameter of the abdominal aortic aneurysm (p>0.05). Advanced age and smoking were independent risk factors for abdominal aortic aneurysm. Conclusion: These results demonstrate that the prevalence of abdominal aortic aneurysm is higher in patients with carotid disease than in the general population. Patients with known carotid disease may be candidates for selective screening for abdominal aortic aneurysm detection

Temporal variations of stroke occurence

© 2017, University of Kragujevac, Faculty of Science. All rights reserved. Stroke is one of leading causes of death worldwide. Different frequency of stroke occurence is observed in days of the week and months in the year, and incidence of stroke has irregular time pattern. We analyzed 516 patients who had acute stroke and were treated in Clinic of Neurology, Clinical Center Kragujevac from January 1, 2013 to January 1, 2014, mean age 72,11 ± 11,52. Statistical analysis is conducted out using the SPSS software version 20.0. We used descriptive statistic, student T-test, chi-square or Fisher exact test. Friday is day we found the most IS and all stroke types occurences, and Wednesday is day we found the most IS in men. We found the most strokes in women younger than 65 years on Wednesday, but in women older than 65 years on Friday. Monday is day with the most admissions to hospital for patients wiThis, and we observed that there is average delay in the refering to the doctor for 1.80 ± 1.44 days. Friday is the day with the most ICH symptom beginings and the most admissions to the hospital, and Saturday is the day with the least symptom beginings and admissions to the hospital in the case of IS and ICH. The most IS occured in winter (in Decembar), and the least in summer (in August). The most ICH occured in May, and the least in July and October. We confirmed that there is a significant weekly variability in the IS symptom onset day

EEG abnormalities as diagnostic and prognostic factor for encephalitis

© 2016, University of Kragujevac, Faculty of Science. All rights reserved. The aim of the study is to examine whether EEG abnormalities in patients with encephalitis might be prognostic and diagnostic factors for final epilepsy outcome and/or be correlated with the severity of the disability. The most frequent causes of encephalitis were HSV, WNV, INF V, MTB, St PN, St AU. There was a highly statistically significant positive correlation between the severity of the EEG abnormalities at the beginning of the disease (r = 0.410, p <0.01) and the ultimate outcome. Electroencephalography in the early stages of encephalitis shows diagnostic and prognostic significance and, in combination with the overall severity of the clinical picture, could contribute to the diagnosis and assessment of outcomes and, ultimately, the correction of treatment and faster recovery of patients. This is particularly true for viral encephalitis

EEG Abnormalities as Diagnostic and Prognostic Factor for Encephalitis

The aim of the study is to examine whether EEG abnormalities in patients with encephalitis might be prognostic and diagnostic factors for final epilepsy outcome and/or be correlated with the severity of the disability

Specific polymorphism 4G/5G gene for PAI-1 as a possible cause of cerebral venous thrombosis: A case report

© 2017, University of Kragujevac, Faculty of Science. All rights reserved. Th rombosis of veins and venous sinus (CVT) is the rare cerebral vascular disorder which makes less than 1% of all strokes. Th rombosis of veins and venous sinuses is picturesquely called “мајоr neurological forger” since it is characterized by very varied clinical picture. Among the various causes of CVT, which can be of infective or non-infective nature, the congenital hyper coagulations especially stand out, diagnosis is based on highly sophisticated diagnostic tests. We present the case of a female patient, 36 years old, who was hospitalized at the Clinic for Neurology in Clinical Center because of the diffuse headache she had for the last few days, with milder right-sided hemiparesis and one generalized tonic-clonic epileptic seizure. With nuclear magnetic resonance (MR/2D venography) the thrombosis of the upper and lower sagittal sinuses is confirmed. By appropriate laboratory tests, as well as by confirmatory immunological and genetic analyses, the impact of the most of the factors is excluded which can contribute to the occurrence of venous thrombosis. The only pathological findings which indicated the possible congenital thrombophilia as the cause of the sagittal sinus thrombosis was the determination of the specific polymorphism of the 4G/5G gene for plasminogen activator inhibitor 1. According to our knowledge, this is the first decribed case of the possible impact of the specific polymorphism of the 4G/5G gene for plasminogen activator inhibitor of 1 on the development of cerebral venous thrombosis

Temporal Variations of Stroke Occurence

Stroke is one of leading causes of death worldwide. Different frequency of stroke occurence is observed in days of the week and months in the year, and incidence of stroke has irregular time pattern. We analyzed 516 patients who had acute stroke and were treated in Clinic of Neurology, Clinical Center Kragujevac from January 1, 2013 to January 1, 2014, mean age 72,11±11,52. Statistical analysis is conducted out using the SPSS software version 20.0. We used descriptive statistic, student T-test, chi-square or Fisher exact test

Specific Polymorphism 4G/5G Gene for PAI-1 as a Possible Cause of Cerebral Venous Thrombosis: A Case Report

Thrombosis of veins and venous sinus (CVT) is the rare cerebral vascular disorder which makes less than 1% of all strokes. Thrombosis of veins and venous sinuses is picturesquely called “мајоr neurological forger” since it is characterized by very varied clinical picture. Among the various causes of CVT, which can be of infective or non-infective nature, the congenital hyper coagulations especially stand out, diagnosis is based on highly sophisticated diagnostic tests