343 research outputs found
Binding between endohedral Na atoms in Si clathrate I; a first principles study
We investigate the binding nature of the endohedral sodium atoms with the
ensity functional theory methods, presuming that the clathrate I consists of a
sheaf of one-dimensional connections of Na@Si cages interleaved in three
perpendicular directions. Each sodium atom loses 30% of the 3s charge to
the frame, forming an ionic bond with the cage atoms; the rest of the electron
contributes to the covalent bond between the nearest Na atoms. The presumption
is proved to be valid; the configuration of the two Na atoms in the nearest
Si cages is more stable by 0.189 eV than that in the Si and
Si cages. The energy of the beads of the two distorted Na atoms is more
stable by 0.104 eV than that of the two infinitely separated Na atoms. The
covalent bond explains both the preferential occupancies in the Si cages
and the low anisotropic displacement parameters of the endohedral atoms in the
Si cages in the [100] directions of the clathrate I.Comment: First page: Affiliation added to PDF and PS versio
An Electron-Tracking Compton Telescope for a Survey of the Deep Universe by MeV gamma-rays
Photon imaging for MeV gammas has serious difficulties due to huge
backgrounds and unclearness in images, which are originated from incompleteness
in determining the physical parameters of Compton scattering in detection,
e.g., lack of the directional information of the recoil electrons. The recent
major mission/instrument in the MeV band, Compton Gamma Ray
Observatory/COMPTEL, which was Compton Camera (CC), detected mere
persistent sources. It is in stark contrast with 2000 sources in the GeV
band. Here we report the performance of an Electron-Tracking Compton Camera
(ETCC), and prove that it has a good potential to break through this stagnation
in MeV gamma-ray astronomy. The ETCC provides all the parameters of
Compton-scattering by measuring 3-D recoil electron tracks; then the Scatter
Plane Deviation (SPD) lost in CCs is recovered. The energy loss rate (dE/dx),
which CCs cannot measure, is also obtained, and is found to be indeed helpful
to reduce the background under conditions similar to space. Accordingly the
significance in gamma detection is improved severalfold. On the other hand, SPD
is essential to determine the point-spread function (PSF) quantitatively. The
SPD resolution is improved close to the theoretical limit for multiple
scattering of recoil electrons. With such a well-determined PSF, we demonstrate
for the first time that it is possible to provide reliable sensitivity in
Compton imaging without utilizing an optimization algorithm. As such, this
study highlights the fundamental weak-points of CCs. In contrast we demonstrate
the possibility of ETCC reaching the sensitivity below erg
cm s at 1 MeV.Comment: 19 pages, 12 figures, Accepted to the Astrophysical Journa
A search for deeply bound kaonic nuclear states
We have measured proton and neutron energy spectra by stopping negative kaons
on liquid helium4. Two distinct peak structures were found on both spectra,
which were assigned to the formation of new kinds of strange stribaryons. In
this paper, we summarize both results.Comment: 7 pages, 3 figures, HYP2003 conference proceeding
Gene Expression and Localization of High-mobility Group Box Chromosomal Protein-1 (HMGB-1) in Human Osteoarthritic Cartilage
We investigated the expression and localization of high-mobility group box chromosomal protein-1 (HMGB-1) in human osteoarthritic (OA) cartilage in relation to the histopathological grade of cartilage destruction, and examined the role of HMGB-1 in the regulation of proinflammatory cytokine expression in chondrocytes. An immunohistochemical study demonstrated that total HMGB-1-positive cell ratios increase as the Osteoarthritis Research Society International (OARSI) histological grade increased. The population of cytoplasmic HMGB-1-positive chondrocytes was especially increased in the deep layers of higher-grade cartilage. The ratios and localization of receptors for advanced glycation end products (RAGE) expression by chondrocytes in Grade 2, 3, and 4 were significantly higher than those in Grade 1. In vitro stimulation with IL-1β, but not TNFα, significantly upregulated the expression of HMGB-1 mRNA by human OA chondrocytes. Both IL-1β and TNFα promoted the translocation of HMGB-1 from nuclei to cytoplasm. IL-1β and TNFα secretions were stimulated at higher levels of HMGB-1. The results of our study suggest the involvement of HMGB-1 in the pathogenesis of cartilage destruction in OA
Ammonia (J,K) = (1,1) to (4,4) and (6,6) inversion lines detected in the Seyfert 2 galaxy NGC 1068
We present the detection of the ammonia (NH3) (J,K) = (1,1) to (4,4) and
(6,6) inversion lines toward the prototypical Seyfert 2 galaxy NGC 1068, made
with the Green Bank Telescope (GBT). This is the first detection of ammonia in
a Seyfert galaxy. The ortho-to-para-NH3 abundance ratio suggests that the
molecule was formed in a warm medium of at least 20 K. For the NH3 column
density and fractional abundance, we find (1.09\pm0.23)\times10^14 cm^-2 and
(2.9\pm0.6)\times10^-8, respectively, from the inner 1.2 kpc of NGC 1068. The
kinetic temperature can be constrained to 80\pm20 K for the bulk of the
molecular gas, while some fraction has an even higher temperature of 140\pm30
K.Comment: 5 pages, 3 figures, accepted by A&
Trends in incidence and mortality of tuberculosis in Japan : a population-based study, 1997–2016
Japan is still a medium-burden tuberculosis (TB) country. We aimed to examine trends in newly notified active TB incidence and TB-related mortality in the last two decades in Japan. This is a population-based study using Japanese Vital Statistics and Japan Tuberculosis Surveillance from 1997 to 2016. We determined active TB incidence and mortality rates (per 100 000 population) by sex, age and disease categories. Joinpoint regression was applied to calculate the annual percentage change (APC) in age-adjusted mortality rates and to identify the years showing significant trend changes. Crude and age-adjusted incidence rates reduced from 33.9 to 13.9 and 37.3 to 11.3 per 100 000 population, respectively. Also, crude and age-adjusted mortality rates reduced from 2.2 to 1.5 and 2.8 to 1.0 per 100 000 population, respectively. Average APC in the incidence and mortality rates showed significant decline both in men (−6.2% and −5.4%, respectively) and women (−5.7% and −4.6%, respectively). Age-specific analysis demonstrated decreases in incidence and mortality rates for every age category, except for the incidence trend in the younger population. Although trends in active TB incidence and mortality rates in Japan have favourably decreased, the rate of decline is far from achieving TB elimination by 2035
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