Tensile Strength of Unidirectional Carbon Fiber-Reinforced Plastic Composites

The tensile strengths of unidirectionally aligned carbon fiber-reinforced plastic (UD-CFRP) were predicted by implementing a spring element model (SEM) that takes into account a stress concentration acting on an intact fiber surface originated from a fracture site in an neighboring fiber. The surface stress concentration was experimentally investigated by implementing multi-fiber fragmentation testing in combination with the SEM simulation. Four types of epoxy materials were selected to explore the effects of matrix polymer properties on the surface stress concentration. The size scaling results, coupled with the results of the SEM simulation, designed to take into account the surface stress concentration, were reasonably consistent with the experimentally obtained data on the tensile strengths of the UD-CFRP composites, irrespective of the differences in the matrix mechanical characteristics. The possible mechanisms by which additional stress concentration is generated on an intact fiber surface were analyzed numerically using the finite element method

The developmental trajectory of attentional orienting to socio-biological cues.

It has been proposed that the orienting of attention in the same direction as another’s point of gaze relies on innate brain mechanisms which are present from birth, but direct evidence relating to the influence of eye gaze cues on attentional orienting in young children is limited. In two experiments, 137 children aged 3–10 years old performed an adapted pro-saccade task with centrally presented uninformative eye gaze, finger pointing and arrow pre-cues which were either congruent or incongruent with the direction of target presentations. When the central cue overlapped with presentation of the peripheral target (Experiment 1), children up to 5 years old had difficulty disengaging fixation from central fixation in order to saccade to the target. This effect was found to be particularly marked for eye gaze cues. When central cues were extinguished simultaneously with peripheral target onset (Experiment 2), this effect was greatly reduced. In both experiments finger pointing cues (image of pointing index finger presented at fixation) exerted a strong influence on saccade reaction time to the peripheral stimulus for the youngest group of children (<5 years). Overall the results suggest that although young children are strongly engaged by centrally presented eye gaze cues, the directional influence of such cues on overt attentional orienting is only present in older children, meaning that the effect is unlikely to be dependent upon an innate brain module. Instead, the results are consistent with the existence of stimulus–response associations which develop with age and environmental experience

Monkeys, Apes, and HumansPrimatology in Japan /

X, 52 p. 19 illus., 10 illus. in color.online res

チンパンジー親子トリオを用いた超高精度全ゲノム配列決定による新規変異率の直接推定

チンパンジー親子トリオ（父親－母親－息子）の 全ゲノム配列を高精度で解明. 京都大学プレスリリース. 2017-11-02.Mutations generate genetic variation and are a major driving force of evolution. Therefore, examining mutation rates and modes are essential for understanding the genetic basis of the physiology and evolution of organisms. Here, we aim to identify germline de novo mutations through the whole-genome surveyance of Mendelian inheritance error sites (MIEs), those not inherited through the Mendelian inheritance manner from either of the parents, using ultra-deep whole genome sequences (>150-fold) from a chimpanzee parent-offspring trio. We identified such 889 MIEs and classified them into four categories based on the pattern of inheritance and the sequence read depth: [i] de novo single nucleotide variants (SNVs), [ii] copy number neutral inherited variants, [iii] hemizygous deletion inherited variants, and [iv] de novo copy number variants (CNVs). From de novo SNV candidates, we estimated a germline de novo SNV mutation rate as 1.48 × 10−8 per site per generation or 0.62 × 10−9 per site per year. In summary, this study demonstrates the significance of ultra-deep whole genome sequencing not only for the direct estimation of mutation rates but also for discerning various mutation modes including de novo allelic conversion and de novo CNVs by identifying MIEs through the transmission of genomes from parents to offspring