Correction: A Genome-Wide Association Study for Diabetic Retinopathy in a Japanese Population: Potential Association with a Long Intergenic Non-Coding RNA

<p>Correction: A Genome-Wide Association Study for Diabetic Retinopathy in a Japanese Population: Potential Association with a Long Intergenic Non-Coding RNA</p

Regional association plot of the region around the SNP rs9362054.

<p>The -log₁₀P values of the Fisher's exact test under the allele model in the GWAS of diabetic retinopathy in stage 1 were plotted against relative chromosomal locations (UCSC human genome 19).</p

Summary of the study strategy.

<p>Summary of the study strategy.</p

SNPs showing associations with diabetic retinopathy (DR) in combined stages 1 and 2 samples with <i>P</i><10⁻³ using the allele model.

<p>SNPs showing associations with diabetic retinopathy (DR) in combined stages 1 and 2 samples with <i>P</i><10⁻³ using the allele model.</p

Associations of rs9362054 in <i>RP1-90L14.1</i> with diabetic retinopathy (DR), proliferative diabetic retinopathy (PDR) and diabetic nephropathy (DN) in each stage and combined stages 1, 2 and 3, using logistic regression under genotype, dominant and recessive models after adjusting for sex, duration of diabetes and HbA1c.

a<p>With additive genetic effect.</p><p>Associations of rs9362054 in <i>RP1-90L14.1</i> with diabetic retinopathy (DR), proliferative diabetic retinopathy (PDR) and diabetic nephropathy (DN) in each stage and combined stages 1, 2 and 3, using logistic regression under genotype, dominant and recessive models after adjusting for sex, duration of diabetes and HbA1c.</p

Clinical features of Japanese patients with type 2 diabetes.

<p>DR: diabetic retinopathy, PDR: proliferative diabetic retinopathy; DN: diabetic nephropathy, SMU: Saitama Medical University Hospital, SSI: Saitama Social Insurance Hospital, KU: Keio University Hospital, NCGM: National Center for Global Health and Medicine Center Hospital.</p><p>Data are % or mean +− SD.</p>a<p><i>P</i><0.05 vs patients without DR.</p><p>Clinical features of Japanese patients with type 2 diabetes.</p

Manhattan plot for the GWAS of diabetic retinopathy in stage 1.

<p><i>P</i> values of the Fisher's exact test under the allele model for SNPs in 446 patients were shown.</p