NMR Spectroscopic Study of the Complexation Behaviors of Deuterated Cyclodextrins and [60]Fullerene

Cyclodextrins (CDxs) have been selectively deuterated using a Ru/C-catalyzed H–D exchange reaction in D₂O. The structures of the deuterated CDxs barely changed and their ¹H NMR spectra became very simple, which made it possible for the deuterated CDxs to be applied to the analysis of CDx complexes. Furthermore, the deuterated CDxs allowed for the existence of the equilibrium between free and complexed CDx to be confirmed, even at rt

[70]Fullerenes Assist the Formation of Phospholipid Bicelles at Low Lipid Concentrations

The incorporation of neutral [70]­fullerenes (C₇₀) led to bicelle formation in a relatively low lipid concentration range from neutral lipid mixtures (DMPC/DHPC). Furthermore, C₇₀ addition resulted in the formation of large bicelles with a radius of ca. 100 nm, in contrast to C₇₀-free bicelles that were formed from anionic lipid mixtures (DMPC/DHPC/DMPG). The stabilization of these bicelles was attributed to C₇₀ incorporation into the membranes