Effect of add-on therapy of tiotropium in COPD treated with theophylline-2

<p><b>Copyright information:</b></p><p>Taken from "Effect of add-on therapy of tiotropium in COPD treated with theophylline"</p><p></p><p>International Journal of Chronic Obstructive Pulmonary Disease 2008;3(1):137-147.</p><p>Published online Jan 2008</p><p>PMCID:PMC2528215.</p><p>© 2008 Kawayama et al, publisher and licensee Dove Medical Press Ltd.</p

Effect of add-on therapy of tiotropium in COPD treated with theophylline-4

<p><b>Copyright information:</b></p><p>Taken from "Effect of add-on therapy of tiotropium in COPD treated with theophylline"</p><p></p><p>International Journal of Chronic Obstructive Pulmonary Disease 2008;3(1):137-147.</p><p>Published online Jan 2008</p><p>PMCID:PMC2528215.</p><p>© 2008 Kawayama et al, publisher and licensee Dove Medical Press Ltd.</p

Effect of add-on therapy of tiotropium in COPD treated with theophylline-3

<p><b>Copyright information:</b></p><p>Taken from "Effect of add-on therapy of tiotropium in COPD treated with theophylline"</p><p></p><p>International Journal of Chronic Obstructive Pulmonary Disease 2008;3(1):137-147.</p><p>Published online Jan 2008</p><p>PMCID:PMC2528215.</p><p>© 2008 Kawayama et al, publisher and licensee Dove Medical Press Ltd.</p

Patients' characteristics.

<p>Patients' characteristics.</p

Cox regression analysis of PFS for NSCLC patients.

<p>Cox regression analysis of PFS for NSCLC patients.</p

ROC curves for PFS and OS.

<p>The ROC curves for 1-year (A) and 2-year (B) PFS of the risk score estimated by Cox regression indicate a substantially improved correlation with 1-year and 2-year PFS. The ROC curves for 1-year (C) and 2-year (D) OS are also shown.</p

Kaplan-Meier analysis of PFS and OS after stratification by IgG titer against selected EGFR-derived peptides in NSCLC patients receiving gefitinib treatment.

<p>Kaplan-Meier plots of PFS (A) and OS (B) in patients showing higher and lower IgG titers against the selected peptides, egfr_41_ 60, egfr_61_80, and egfr_481_500, are shown. Lower and higher IgG titers were defined by their median values.</p

Multivariate analysis of OS.

<p>Multivariate analysis of OS.</p

Relation between expression score for ERCC1 and various patient characteristics.

a<p>Determined by Fisher’s exact test.</p

Multivariate analysis of PFS.

<p>Multivariate analysis of PFS.</p