14 research outputs found

    ガクサイテキ ブンヤ ニオケル ガクシ カテイ コウチク オ シヤ ニ イレタ ジュギョウ ヒョウカ アンケート ト ソノ カツヨウ

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    FD活動は、学士課程において平成20年度から、全ての大学においてその実施が義務化された。 大学教育のなかでも、学際的な学問分野をどの様にして体系化いくかについては課題となっている。 現在授業評価アンケートは、多くの大学で実施されているのが、その内容については大学の教育目標と の関連づけなどに改善の余地がある。本稿では、学際的な分野における授業評価アンケートについて、 ディプローマポリシーに関連する能力達成の項目を導入し、カリキュラム全体のチェックを行うことで、 組織的な評価をおこなう。これを組織的なFD活動に反映させ、学士課程の構築を目指すことの可能性について考察する。Activity for faculty development (FD) was obligated in the course of bachelor in all the university from 2008. An establishment for systematic planning of curriculum for general education and cultural studies in university education. Although class evaluation questionnaires are already employed in most of the univesities,some problems such as lacking the object of education in each university remain to be improved.Qualification of the undergraduate program is required for establishment of the systematic curriculum for various levels or aims of study for students. In the present paper,we discuss on the significance of the reflection of class evaluation questionnaires included the achievement of competences in the class to check the valance of curriculum for evaluation of the university education.We also discuss on the possibility of reflection of the class evaluation questionnaires for the appropriate FD activities that have direction to the qualification of undergraduate program

    Detecting pancreatic β-cell cfDNA

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    Aims/Introduction: Several research groups have reported methods for quantifying pancreatic beta cell (β-cell) injury by measuring β-cell-specific CpG unmethylation of the insulin gene in circulation using digital droplet PCR or next-generation sequencing. However, these methods have certain disadvantages, such as the need to consider the background signal owing to the small number of target CpG sites and the need for unique equipment. Materials and Methods: We established a novel method for detecting four CpG unmethylations of the insulin gene using two-step amplification refractory mutation system PCR. We applied it to type 1 diabetes (T1D) patients with a wide range of disease durations and to healthy adults. Results: The assay showed high linearity and could detect a single copy of unmethylated insulin DNA in experiments using methylated and unmethylated plasmid DNA. The unmethylated insulin DNA level in the type 1 diabetes group, whose β-cell mass was considerably reduced, was similar to that of healthy adults. An inverse correlation was observed between copy number and disease duration in patients with unmethylated insulin DNA-positive type 1 diabetes. Conclusions: We developed a novel method for detecting unmethylated insulin DNA in circulation that can be performed using a conventional real-time PCR system. This method would be useful for analyzing dynamic profiles of β-cells in human disease such as type 1 diabetes
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