Short- and long-term effects of transfers on football clubs' sport performance

One of the important elements of football club quality management is the sale and purchase of player’s cards. These activities have important implications for the financial and sport performance of football clubs. The purpose of this paper is to determine how players transfers affect football teams’ sport performance. Data on transfers and sport performance came from available databases. They covered the period from 2004/05 to 2018/19 (before the pandemic). For data analysis, a series of hierarchical analysis of regression were conducted. The results show that there is an effect of transfers on football teams’ sport performance but it explains a relatively small amount of football club’s sport performance. The impact from a transfer in a given year affects sport performance not only in the same year, but also in subsequent years. However, the effect of transfer disappears when control variables are introduced.  Thus, the general conclusion from the study is that there is no overall effect of transfers on teams’ sport performance. The analyses were conducted only on clubs from the 5 major European leagues and football clubs that were continuously present in the top division. Due to the fact that it included mainly the strongest clubs, the results are relevant for clubs wishing to build up their sporting position on the European market. It is less relevant for weaker clubs. The study consisted of using data over a period of several years, which provides an opportunity to trace the dynamics of change and long-term effects, which is rarely analyzed in the sports literature

Rzadki przypadek rzekomego tętniaka tętnicy wątrobowej

Tętniaki tętnicy wątrobowej należą do rzadkich, ale potencjalnie zagrażających życiu patologii naczyniowych. Są one zwykle wykrywane przypadkowo podczas badań obrazowych w trakcie diagnostyki z innych powodów. W pracy przedstawiono bardzo rzadki przypadek tętniaka rzekomego gałęzi tętnicy wątrobowej z przetoką do lewej gałęzi żyły wrotn

Rare case of hepatic artery pseudoaneurysm

Hepatic artery aneurysms are rare, but potentially life-threatening vascular pathologies. They are usually discovered incidentally during imaging diagnostics of different pathologies. The study presented a rare case of hepatic artery pseudoaneurym with a fistula to the left branch of the portal vein

Immunotherapy in Bladder Cancer: Current Methods and Future Perspectives

Bladder cancer is one of the most significant genitourinary cancer, causing high morbidity and mortality in a great number of patients. Over the years, various treatment methods for this type of cancer have been developed. The most common is the highly efficient method using Bacillus Calmette-Guerin, giving a successful effect in a high percentage of patients. However, due to the genetic instability of bladder cancer, together with individual needs of patients, the search for different therapy methods is ongoing. Immune checkpoints are cell surface molecules influencing the immune response and decreasing the strength of the immune response. Among those checkpoints, the PD-1 (programmed cell death protein-1)/PD-L1 (programmed cell death protein ligand 1) inhibitors aim at blocking those molecules, which results in T cell activation, and in bladder cancer the use of Atezolizumab, Avelumab, Durvalumab, Nivolumab, and Pembrolizumab has been described. The inhibition of another pivotal immune checkpoint, CTLA-4 (cytotoxic T cell antigen), may result in the mobilization of the immune system against bladder cancer and, among anti-CTLA-4 antibodies, the use of Ipilimumab and Tremelimumab has been discussed. Moreover, several different approaches to successful bladder cancer treatment exists, such as the use of ganciclovir and mTOR (mammalian target of rapamycin) kinase inhibitors, IL-12 (interleukin-12) and COX-2 (cyclooxygenase-2). The use of gene therapies and the disruption of different signaling pathways are currently being investigated. Research suggests that the combination of several methods increases treatment efficiency and the positive outcome in individual

The Impact of Surgical Techniques in Patients with Rectal Cancer on Spine Mobility and Abdominal Muscle Strength—A Prospective Study

The aim of this non-randomized study was to evaluate the impact of spine joint mobility and chest mobility on inhalation and exhalation, and to assess the abdominal muscle strength in patients undergoing surgery for colorectal cancer with one of the following methods: anterior resection, laparoscopic anterior resection or abdominoperineal resection. In patients who were successively admitted to the Department of Surgical Oncology at the Oncology Center in Bydgoszcz, the impact of spine joint mobility, muscle strength and chest mobility on inhalation and exhalation wasassessed three times, i.e., at their admission and three and six months after surgery. The analysis included 72 patients (18 undergoing abdominoperineal resection, the APR group; 23 undergoing laparoscopic anterior resection, the LAR group; and 31 undergoing anterior resection, the AR group). The study groups did not differ in terms of age, weight, height, BMIor hospitalization time (p > 0.05). Three months after surgery, reductions in spine joint mobility regarding flexion, extension and lateral flexion, as well asreductions in the strength of the rectus abdominis and oblique muscles, were noted in all study groups (p < 0.05). In comparison between the groups, the lowest values suggesting the greatest reduction in the range of mobility were recorded in the APR group. Surgical treatment and postoperative management in colorectal cancer patients caused a reduction in spine mobility, abdominal muscle strength and chest mobility. The patients who experienced those changes most rapidly and intensively werethose undergoing abdominoperineal resection