L'economia del talent, les ciutats i els parcs científics

Parcs científics/tecnològics: clau per crear un entorn on el talent empresarial emigrat pot retornar per treballar en condicions favorables únique

The talent economy, cities and science parks

Science/Technology Parks: key to creating an environment where migrated entrepreneurial talent can return to work under unique favorable condition

Enterprise: creation, development and growth : Book review

The subject of this book is divided into twelve chapters with the first chapter starting with an overview of the enterprise concept. This chapter also highlights how individuals show enterprise in many situations. The remaining chapters cover the spread of ideas such as the entrepreneurial economy, enterprise support system, building and managing an enterprise, management and the large enterprise, public and voluntary enterprise, personal development. group work and networking. Finally, there is a chapter on individuality, enterprise and the future

English football in a post-Brexit world: Kane we do it?

As English football fans took to the streets to celebrate the national team's victories in the World Cup and then mourned losing to Croatia, it's worth reflecting on the state of English football in a post-Brexit world. For some, the prospects are good if the flood of foreign-born players dries up and local teams are again made up of locals, writes Tom Cannon

Identifying galaxy candidates in WSRT HI imaging of ultra-compact high velocity clouds

Ultra-compact high velocity clouds (UCHVCs) were identified in the ALFALFA HI survey as potential gas-bearing dark matter halos. Here we present higher resolution neutral hydrogen (HI) observations of twelve UCHVCS with the Westerbork Synthesis Radio Telescope (WSRT). The UCHVCs were selected based on a combination of size, isolation, large recessional velocity and high column density as the best candidate dark matter halos. The WSRT data were tapered to image the UCHVCs at 210" (comparable to Arecibo) and 105" angular resolution. In a comparison of the single-dish to interferometer data, we find that the line flux recovered in the WSRT observations is comparable to that from the single-dish ALFALFA data. In addition, any structure seen in the ALFALFA data is reproduced in the WSRT maps at the same angular resolution. At 210'" resolution all the sources are generally compact with a smooth HI morphology, as expected from their identification as UCHVCs. At the higher angular resolution, a majority of the sources break into small clumps contained in a diffuse envelope. These UCHVCs also have no ordered velocity motion and are most likely Galactic halo clouds. We identify two UCHVCs, AGC 198606 and AGC 249525, as excellent galaxy candidates based on maintaining a smooth HI morphology at higher angular resolution and showing ordered velocity motion consistent with rotation. A third source, AGC 249565, lies between these two populations in properties and is a possible galaxy candidate. If interpreted as gas-bearing dark matter halos, the three candidate galaxies have rotation velocities of 8-15 km/s, HI masses of 0.6-50 x 10^5 Msun, HI radii of 0.3-2 kpc, and dynamical masses of 2-20 x 10^7 Msun for a range of plausible distances. These are the UCHVCs with the highest column density values in the ALFALFA HI data and we suggest this is the best way to identify further candidates.Comment: Accepted for publication in A&A. 26 pages, 19 figures, 5 table

Disulfide bridge formation between SecY and a translocating polypeptide localizes the translocation pore to the center of SecY

During their biosynthesis, many proteins pass through the membrane via a hydrophilic channel formed by the heterotrimeric Sec61/SecY complex. Whether this channel forms at the interface of multiple copies of Sec61/SecY or is intrinsic to a monomeric complex, as suggested by the recently solved X-ray structure of the Methanococcus jannaschii SecY complex, is a matter of contention. By introducing a single cysteine at various positions in Escherichia coli SecY and testing its ability to form a disulfide bond with a single cysteine in a translocating chain, we provide evidence that translocating polypeptides pass through the center of the SecY complex. The strongest cross-links were observed with residues that would form a constriction in an hourglass-shaped pore. This suggests that the channel makes only limited contact with a translocating polypeptide, thus minimizing the energy required for translocation

The importance of forecasting regional wind power ramping: a case study for the UK

In recent years there has been a significant change in the distribution of wind farms in Great Britain, with a trend towards very large offshore farms clustered together in zones. However, there are concerns these clusters could produce large ramping events on time scales of less than 6 hours as local meteorological phenomena simultaneously impact the production of several farms. This paper presents generation data from the wind farms in the Thames Estuary (the largest cluster in the world) for 2014 and quantifies the high frequency power ramps. Based on a case study of a ramping event which occurred on 3rd November 2014, we show that due to the large capacity of the cluster, a localised ramp can have a significant impact on the cost of balancing the power system on a national level if it is not captured by the forecast of the system operator. The planned construction of larger offshore wind zones will exacerbate this problem. Consequently, there is a need for accurate regional wind power forecasts to minimise the costs of managing the system. This study shows that state-of-the-art high resolution forecast models have capacity to provide valuable information to mitigate this impact

Disulfide bridge formation between SecY and a translocating polypeptide localizes the translocation pore to the center of SecY

During their biosynthesis, many proteins pass through the membrane via a hydrophilic channel formed by the heterotrimeric Sec61/SecY complex. Whether this channel forms at the interface of multiple copies of Sec61/SecY or is intrinsic to a monomeric complex, as suggested by the recently solved X-ray structure of the Methanococcus jannaschii SecY complex, is a matter of contention. By introducing a single cysteine at various positions in Escherichia coli SecY and testing its ability to form a disulfide bond with a single cysteine in a translocating chain, we provide evidence that translocating polypeptides pass through the center of the SecY complex. The strongest cross-links were observed with residues that would form a constriction in an hourglass-shaped pore. This suggests that the channel makes only limited contact with a translocating polypeptide, thus minimizing the energy required for translocation

The First Two Years of Electromagnetic Follow-Up with Advanced LIGO and Virgo

We anticipate the first direct detections of gravitational waves (GWs) with Advanced LIGO and Virgo later this decade. Though this groundbreaking technical achievement will be its own reward, a still greater prize could be observations of compact binary mergers in both gravitational and electromagnetic channels simultaneously. During Advanced LIGO and Virgo's first two years of operation, 2015 through 2016, we expect the global GW detector array to improve in sensitivity and livetime and expand from two to three detectors. We model the detection rate and the sky localization accuracy for binary neutron star (BNS) mergers across this transition. We have analyzed a large, astrophysically motivated source population using real-time detection and sky localization codes and higher-latency parameter estimation codes that have been expressly built for operation in the Advanced LIGO/Virgo era. We show that for most BNS events the rapid sky localization, available about a minute after a detection, is as accurate as the full parameter estimation. We demonstrate that Advanced Virgo will play an important role in sky localization, even though it is anticipated to come online with only one-third as much sensitivity as the Advanced LIGO detectors. We find that the median 90% confidence region shrinks from ~500 square degrees in 2015 to ~200 square degrees in 2016. A few distinct scenarios for the first LIGO/Virgo detections emerge from our simulations.Comment: 17 pages, 11 figures, 5 tables. For accompanying data, see http://www.ligo.org/scientists/first2year