Multivariate model results.

<p><i>Results of the final multivariate 3-year overall survival (OS) model: Hazard rate (HR) with its 95% confidence interval (CI) and P-value based on the Cox regression model.</i></p

3-year overall survival (OS) curves for the entire cohort stratified by the ECOG score.

<p>The hazard rates of groups 1, 2, 3, 4 relative to group ECOG = 0 are 2.85, 3.89, 3.82, 24.58, respectively. Notice the clear separation of the group ECOG = 4 from the rest of the population. However, group ECOG = 4 contains only 8 patients. Optimal stratification of the population into two groups thus separates group ECOG = 0 (109 patients) from the rest of the population (334 patients).</p

Summary of all the prognostic factors.

<p><i>Results of the univariate 3-year overall survival (OS) analyses: hazard rate (HR) with its 95% confidence interval (CI) and P-value based on the Cox regression model. Descriptive statistics of all the prognostic factors.</i></p

Overall survival (OS) and Progression-free survival (PFS) curves for the entire cohort.

<p>Complete follow-up.</p

Comparison of the novel scores with the existing ones.

<p><i>Results from comparison of newly constructed scores (ABE4-Score and ABE3-Score) with several existing scoring systems. The measure of concordance compares the model discrimination, the Akaike Information Criterion (AIC) compares the model fit.</i></p

Summary of the validation of the ABE scoring systems.

<p><i>Results of the univariate 3-year overall survival analysis in the training and the validation data sets: hazard rate (HR) with its 95% CI and P-value based on the Cox regression model. Reference group in all regression models is the lowest risk group. The measure of concordance compares the model discrimination.</i></p

Overall survival (OS) curves for the entire cohort stratified by the 4-level scoring systems: the proposed novel ABE4-Score, and the classical IPI, AA-IPI, and E-IPI scores.

<p>Overall survival (OS) curves for the entire cohort stratified by the 4-level scoring systems: the proposed novel ABE4-Score, and the classical IPI, AA-IPI, and E-IPI scores.</p

Overall survival (OS) curves for the entire cohort stratified by the 3-level scoring systems: the proposed novel ABE3-Score, and the classical R-IPI, and ALC/RIPI scores.

<p>Overall survival (OS) curves for the entire cohort stratified by the 3-level scoring systems: the proposed novel ABE3-Score, and the classical R-IPI, and ALC/RIPI scores.</p

Summary of the scoring systems.

<p><i>Distribution and outcome of patients according to the compared risk scoring systems. Results of the univariate 3-year overall survival analysis: estimated 3-year overall survival (OS) with its 95% confidence interval (CI), hazard rate (HR) with its 95% CI and P-value based on the Cox regression model. Reference group in all regression models is the lowest risk group.</i></p