New Frontiers in Organ Preservation and Hepatoprotection

This editorial aims to summarize the 13 scientific articles published in the Special Issue entitled “New Frontiers in Organ Preservation and Hepatoprotection” [...

Reproducibility.

<p>Reproducibility was assessed by repeating shots. (A, B) Two cavities for the TAG bullet at 900 m/s appear similar except for small parts created by unpredictable fragments. (C) A strong correlation of the volumes between all first and second shots is found (n = 16), showing high reproducibility. (D) The correlation, i.e. reproducibility is highest for NVU and TSX.</p

Exiting fragments.

<p>The exiting fragments where collected and weighed to calculate the deposited energy. Fragments are shown for increasing speeds from top to bottom. Pictures were only taken when fragments exited the soap block.</p

Bullet types.

<p>Four commercially available bullets were used for the experiments.</p

Cutting vs. CT-Method.

<p>(A) The cutting method results in piecewise truncated cones which cannot accurately represent elliptical cross-sections. (B) Using the CT images, an accurate model of the cavity is created. (C) For both methods, the cross-sectional area is plotted over the depth. (D) The cavity volumes of 32 blocks measured by both methods show a strong correlation.</p

Deforming lead-containing bullet (NVU).

<p>(A–D) Cavities at increasing energies. Many metal fragments are visible. (E) Cavity volume plotted over deposited energy with higher for the quadratic regression than for linear regression. (F) Ratio of volume and deposited energy increases with deposited energy ().</p

Partially fragmenting copper bullet (TAG).

<p>(A–D) Cavities at increasing energies. The aluminum tip which supports the bullet expansion can be seen at similar depths. (E) Cavity volume plotted over deposited energy with linear and quadratic regression curves showing similar . (F) Ratio of volume and deposited energy is constant over the deposited energy.</p

Number of fragments.

<p>(A) Significantly more fragments occur for the lead-based bullet compared to all lead-free bullets (). No fragments occur for the brass bullet. (A–E) The number of metal fragments over the deposited energy.</p

CT method.

<p>(A) CT slice of the soap block with a cavity. Air outside the block and in the cavity appears black. The soap appears gray and the metal fragments as small white spots. (B) Segmented cavity shown in blue. (C, D) 3D renderings of the virtually cut soap block and the segmented cavity. (E) 3D rendering of the cavity. (F) Cavity with lead fragments. (G) Cloud of lead fragments.</p