Group quantization of parametrized systems II. Pasting Hilbert spaces

The method of group quantization described in the preceeding paper I is extended so that it becomes applicable to some parametrized systems that do not admit a global transversal surface. A simple completely solvable toy system is studied that admits a pair of maximal transversal surfaces intersecting all orbits. The corresponding two quantum mechanics are constructed. The similarity of the canonical group actions in the classical phase spaces on the one hand and in the quantum Hilbert spaces on the other hand suggests how the two Hilbert spaces are to be pasted together. The resulting quantum theory is checked to be equivalent to that constructed directly by means of Dirac's operator constraint method. The complete system of partial Hamiltonians for any of the two transversal surfaces is chosen and the quantum Schr\"{o}dinger or Heisenberg pictures of time evolution are constructed.Comment: 35 pages, latex, no figure

Quantizations on the circle and coherent states

We present a possible construction of coherent states on the unit circle as configuration space. Our approach is based on Borel quantizations on S^1 including the Aharonov-Bohm type quantum description. The coherent states are constructed by Perelomov's method as group related coherent states generated by Weyl operators on the quantum phase space Z x S^1. Because of the duality of canonical coordinates and momenta, i.e. the angular variable and the integers, this formulation can also be interpreted as coherent states over an infinite periodic chain. For the construction we use the analogy with our quantization and coherent states over a finite periodic chain where the quantum phase space was Z_M x Z_M. The coherent states constructed in this work are shown to satisfy the resolution of unity. To compare them with canonical coherent states, also some of their further properties are studied demonstrating similarities as well as substantial differences.Comment: 15 pages, 4 figures, accepted in J. Phys. A: Math. Theor. 45 (2012) for the Special issue on coherent states: mathematical and physical aspect

Chronic calcium signaling in IgE⁺ B cells limits plasma cell differentiation and survival

In contrast to other antibody isotypes, B cells switched to IgE respond transiently and do not give rise to long-lived plasma cells (PCs) or memory B cells. To better understand IgE-BCR-mediated control of IgE responses, we developed whole-genome CRISPR screening that enabled comparison of IgE+ and IgG1+ B cell requirements for proliferation, survival, and differentiation into PCs. IgE+ PCs exhibited dependency on the PI3K-mTOR axis that increased protein amounts of the transcription factor IRF4. In contrast, loss of components of the calcium-calcineurin-NFAT pathway promoted IgE+ PC differentiation. Mice bearing a B cell-specific deletion of calcineurin B1 exhibited increased production of IgE+ PCs. Mechanistically, sustained elevation of intracellular calcium in IgE+ PCs downstream of the IgE-BCR promoted BCL2L11-dependent apoptosis. Thus, chronic calcium signaling downstream of the IgE-BCR controls the self-limiting character of IgE responses and may be relevant to the accumulation of IgE-producing cells in allergic disease

Dihedral symmetry of periodic chain: quantization and coherent states

Our previous work on quantum kinematics and coherent states over finite configuration spaces is extended: the configuration space is, as before, the cyclic group Z_n of arbitrary order n=2,3,..., but a larger group - the non-Abelian dihedral group D_n - is taken as its symmetry group. The corresponding group related coherent states are constructed and their overcompleteness proved. Our approach based on geometric symmetry can be used as a kinematic framework for matrix methods in quantum chemistry of ring molecules.Comment: 13 pages; minor changes of the tex

Unveiling the B cell receptor structure

Molecular structures provide a road map for understanding and controlling B cell receptor activation

Coherent states on the circle

We present a possible construction of coherent states on the unit circle as configuration space. In our approach the phase space is the product Z x S^1. Because of the duality of canonical coordinates and momenta, i.e. the angular variable and the integers, this formulation can also be interpreted as coherent states over an infinite periodic chain. For the construction we use the analogy with our quantization over a finite periodic chain where the phase space was Z_M x Z_M. Properties of the coherent states constructed in this way are studied and the coherent states are shown to satisfy the resolution of unity.Comment: 7 pages, presented at GROUP28 - "28th International Colloquium on Group Theoretical Methods in Physics", Newcastle upon Tyne, July 2010. Accepted in Journal of Physics Conference Serie

Automorphisms of the fine grading of sl(n,C) associated with the generalized Pauli matrices

We consider the grading of $sl(n,\mathbb{C})$ by the group $\Pi_n$ of generalized Pauli matrices. The grading decomposes the Lie algebra into $n^2-1$ one--dimensional subspaces. In the article we demonstrate that the normalizer of grading decomposition of $sl(n,\mathbb{C})$ in $\Pi_n$ is the group $SL(2, \mathbb{Z}_n)$, where $\mathbb{Z}_n$ is the cyclic group of order $n$. As an example we consider $sl(3,\mathbb{C})$ graded by $\Pi_3$ and all contractions preserving that grading. We show that the set of 48 quadratic equations for grading parameters splits into just two orbits of the normalizer of the grading in $\Pi_3$

Symmetries of the finite Heisenberg group for composite systems

Symmetries of the finite Heisenberg group represent an important tool for the study of deeper structure of finite-dimensional quantum mechanics. As is well known, these symmetries are properly expressed in terms of certain normalizer. This paper extends previous investigations to composite quantum systems consisting of two subsystems - qudits - with arbitrary dimensions n and m. In this paper we present detailed descriptions - in the group of inner automorphisms of GL(nm,C) - of the normalizer of the Abelian subgroup generated by tensor products of generalized Pauli matrices of orders n and m. The symmetry group is then given by the quotient group of the normalizer.Comment: Submitted to J. Phys. A: Math. Theo

Group theoretical construction of mutually unbiased bases in Hilbert spaces of prime dimensions

Mutually unbiased bases in Hilbert spaces of finite dimensions are closely related to the quantal notion of complementarity. An alternative proof of existence of a maximal collection of N+1 mutually unbiased bases in Hilbert spaces of prime dimension N is given by exploiting the finite Heisenberg group (also called the Pauli group) and the action of SL(2,Z_N) on finite phase space Z_N x Z_N implemented by unitary operators in the Hilbert space. Crucial for the proof is that, for prime N, Z_N is also a finite field.Comment: 13 pages; accepted in J. Phys. A: Math. Theo