2 research outputs found

    Enquête ethnobotanique à propos des plantes utilisées dans le traitement de l’hypertension artérielle dans la Région autonome du Grand Lomé

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    Pertinence ethnopharmacologique : Le coĂ»t de la prise en charge de l’hypertension est plus Ă©levĂ© chez les patients Ă  faible revenu financier.  D’oĂą l’utilisation frĂ©quente de la mĂ©decine traditionnelle. Cette Ă©tude pourrait rĂ©vĂ©ler de nouveaux usages pour des plantes mĂ©dicinales dĂ©jĂ  connues, ainsi que pour plusieurs plantes mĂ©dicinales inconnues. Objectif de l’étude : L’objectif de ce travail est d’identifier les plantes utilisĂ©es pour traiter l’hypertension dans la RĂ©gion Autonome du Grand LomĂ©. MatĂ©riels et MĂ©thodes : Il s’agissait d’une enquĂŞte ethnobotanique menĂ©e dans la RĂ©gion Autonome du Grand LomĂ© sur une pĂ©riode de six mois d’avril Ă  septembre 2021.  L’accent a Ă©tĂ© mis sur la collecte d’informations sur les plantes mĂ©dicinales utilisĂ©es dans le traitement de l’hypertension artĂ©rielle chez les herboristes du marchĂ© en utilisant la mĂ©thode « Achat en Triplet de Recettes MĂ©decinale (ATRM) Â». RĂ©sultats : Nous avons visitĂ© 18 marchĂ©s et rencontrĂ© 108 herboristes. Les herboristes Ă©taient des hommes dans 79,62 % des cas.  L’enquĂŞte a identifiĂ© 36 espèces de plantes mĂ©dicinales regroupĂ©es en 24 familles de plantes.  La famille des Verbenaceae est la famille la plus frĂ©quemment citĂ©e de ces espèces, et la famille des Fabaceae a le plus grand nombre d’espèces rĂ©pertoriĂ©es. Le Lippia multiflora Moldenke Ă©tait l’espèce la plus citĂ©e par les herboristes. Les parties utilisĂ©es Ă©taient des tiges feuillĂ©es dans 43,5%. Le processus de prĂ©paration de ces plantes comprenait la dĂ©coction (72,7 %) et la macĂ©ration (15,8 %). L’administration par voie orale Ă©tant le principal mode d’administration. Conclusion : La flore de la RĂ©gion Autonome du Grand LomĂ© contient une variĂ©tĂ© de plantes mĂ©dicinales utilisĂ©es pour traiter l’hypertension artĂ©rielle. La dĂ©monstration de leurs effets antihypertenseurs par des tests pharmacologiques garantira que leur utilisation est sĂ©curisĂ©e.   Ethnopharmacological relevance: The cost of managing hypertension is greater for patients with low financial income.  Hence, the frequent use of traditional medicine. This study may uncover new uses for already known medicinal plants, as well as several unknown medicinal plants. Aim of the study: The aim of this work is to identify the plants used to treat hypertension in the Autonomous Region of Greater Lome. Materials and Methods: This was an ethnobotanical survey conducted in the Autonomous Region of Greater Lome over a period of six months from April to September 2021.  The focus was on gathering information about medicinal plants used in the management of hypertension in market herbalists using the “Achat en Triplet de Recettes MĂ©decinale” (ATRM) method. Results: We visited 18 markets and met 108 herbalists.  Herbalists were male in 79.62% of cases.  The survey identified 36 species of medicinal plants grouped into 24 plants families.  The Verbenaceae family is the most frequently cited family of these species, and the Fabaceae family has the highest number of listed species. Lippia multiflora Moldenke was the species most cited by herbalists. The parts used were leafy stem in 43.5%. The preparation process for these antihypertensive plants involved decoction (72.7%) and maceration (15.8), with oral administration being the primary mode of administration. Conclusion: The Greater Lome Autonomous Region's flora contains a variety of medicinal plants that are used to treat hypertension.  Demonstrating their antihypertensive effects through pharmacological tests will ensure their use is secure

    Diuretic effects and subacute toxicity of Trema orientalis Linn leave extract in wistar rats

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    Trema Orientalis is a medicinal plant used in the treatment of cardiovascular diseases including hypertension. The present study was undertaken to investigate phytochemical compounds, diuretic activity and subacute toxicity of the hydromethanolic leaf extracts of Trema orientalis. Phytochemical analysis carried out through color and precipitation reactions revealed the presence of many metabolites. The measurement of diuretic activity carried out by saline overload with 0.9% NaCl at a dose of 50 mL/kg in wistar rats showed that the hydromethanolic extract of Trema orientalis leaves had diuretic activity at a dose of 200 mg/kg of body weight. However, this diuretic activity was relatively low compared to the action of the reference molecule, furosemide. The study of the subacute toxicity of the extract took place over 28 days. No significant difference was recorded in the body weights during the 28 days of the study.  Likewise, the weight of the organs collected after sacrifice of the rats and their macroscopic aspects did not show any significant difference with those of the control group. The extract increased the count of white and red blood cells as wells as platelets, practically at the two doses used and caused a decrease in ALT at the dose of 500 mg/kg. The extract could have a beneficial effect like a boosting immunity and would not present any toxicity at these doses. Keywords: phytochemical, diuretic, subacute toxicity, Trema orientali
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