Legitimate Physical Education - Emphasis on the Education

Many educators and members of the lay public have differing definitions and understandings of school physical education. Based largely on personal experience or perception, many believe that school physical education should merely be a time during the day where children and adolescents are physically active in an effort to produce healthy outcomes. However, this is not only an improbable outcome, it greatly limits opportunities for children to become proficient within the psychomotor learning domain. Because school physical education is the only subject area where the physical domain is strictly addressed, the purpose of this essay is to define, affirm, and depict an alternative to merely providing a fun and active curriculum in physical education for students. This alternative is known as “legitimate physical education,” and provides children with a true learning experience that can produce physically educated adults who have the skills, knowledge, and desire to engage in healthy and active lifestyles

Characterization of a murine model of monocrotaline pyrrole-induced acute lung injury

<p>Abstract</p> <p>Background</p> <p>New animal models of chronic pulmonary hypertension in mice are needed. The injection of monocrotaline is an established model of pulmonary hypertension in rats. The aim of this study was to establish a murine model of pulmonary hypertension by injection of the active metabolite, monocrotaline pyrrole.</p> <p>Methods</p> <p>Survival studies, computed tomographic scanning, histology, bronchoalveolar lavage were performed, and arterial blood gases and hemodynamics were measured in animals which received an intravenous injection of different doses of monocrotaline pyrrole.</p> <p>Results</p> <p>Monocrotaline pyrrole induced pulmonary hypertension in Sprague Dawley rats. When injected into mice, monocrotaline pyrrole induced dose-dependant mortality in C57Bl6/N and BALB/c mice (dose range 6–15 mg/kg bodyweight). At a dose of 10 mg/kg bodyweight, mice developed a typical early-phase acute lung injury, characterized by lung edema, neutrophil influx, hypoxemia and reduced lung compliance. In the late phase, monocrotaline pyrrole injection resulted in limited lung fibrosis and no obvious pulmonary hypertension.</p> <p>Conclusion</p> <p>Monocrotaline and monocrotaline pyrrole pneumotoxicity substantially differs between the animal species.</p

Role for miR-204 in human pulmonary arterial hypertension

Reduced miR-204 expression facilitates the excessive proliferation and apoptosis resistance of pulmonary artery smooth muscle cells characteristic of human pulmonary arterial hypertension

Urban teachers' use of productive and reproductive teaching styles within the confines of the National Curriculum for Physical Education

Etude des pratiques pédagogiques d'enseignants britanniques en milieu urbain : leçons filmées et codées avec un instrument d'observation systématique. Comparaison des styles d'enseignement de cet échantillon urbain avec ceux d'un échantillon rural étudié précédemment