Method of optical treatment

US7506983; US7506983 B2; US7506983B2; US7,506,983; US 7,506,983 B2; 7506983; Application No. 10/954,631Inventor name used in this publication: Chi Ho ToInventor name used in this publication: Siu Yin LamUSVersion of Recor

LED Traffic Light as Communication Device

The visible light from an LED (light emitting diode) traffic light can be modulated and encoded with information. Hence, it can be used for the broadcasting of audio messages or any traffic or road information. Essentially all LED traffic lights can be used as communications devices. The paper focuses on the description of an audio information system made up of high brightness, visible light emitting diodes (LEDs) in which one or more LEDs are modulated and encoded with audio messages. The system also comprises a receiver combined with a speaker which is located at a distance from the LED traffic light. The receiver is designed to demodulate the optically transmitted audio information and broadcast the messages with the speaker. The optical link employs intensity modulation with direct detection. The audio information system implemented on an LED traffic light can provide the function of open space, wireless broadcasting of audio messages.published_or_final_versio

Snapshots for intra- and inter-ocular differences at retinal proteins levels

We attempted to study the intra- and inter-animal variations of protein expressions in chick retina using two-dimensional electrophoresis (2-DE). The posterior retinas of 10 day-old chicks were harvested. The proteins were extracted and 2-DE protein profiles between two eyes of the same individual and among different animals were compared and analysed using Melanie gel analysis software. Computerised Melanie gel analysis showed a high similarity of 83.1 ± 2.1% (mean ± SEM, n=3) between the protein profiles of right and left retinas from the same animal. However, this percentage dropped to 64.1 ± 3.1% (Mean ± SEM, n=3) when comparing between different animal samples. We have shown that there were good similarities in intra-animal comparison but poor in inter-animal comparison. We have documented the caveat in comparing the protein profiles between different animals where apparent differentially display protein could actually be a false positive signal. The finding highlighted the potential usefulness of the proteomic approach in basic eye research where comparison between control and experimental tissues could be carried out in the same animal, rather than using different animals

Infrapatellar fat pad adipose-derived stem cells co-cultured with articular chondrocytes from osteoarthritis patients exhibit increased chondrogenic gene expression.

AIM: The variable results in clinical trials of adipose tissue-derived stem cells (ASCs) for chondral defects may be due to the different ex vivo culture conditions of the ASCs which are implanted to treat the lesions. We sought to determine the optimal in vitro chondrocyte co-culture condition that promotes infrapatellar fat pad-derived (IFPD) ASC chondrogenic gene expression in a novel co-culture combination. METHODS: In our study, we utilized an in vitro autologous co-culture of IFPD ASCs and articular chondrocytes derived from Kellgren-Lawrence Grade III/IV osteoarthritic human knee joints at ASC-to-chondrocyte seeding log ratios of 1:1, 10:1, and 100:1. Gene expression following in vitro co-culture was quantified by RT-qPCR with a panel comprising COL1A1, COL2A1, COL10A1, L-SOX5, SOX6, SOX9, ACAN, HSPG2, and COMP for chondrogenic gene expression. RESULTS: The chondrogenic gene expression profiles from co-cultures were greater than would be expected from an expression profile modeled from chondrocyte and ASC-only monocultures. Additionally, chondrogenic gene expression decreased with increasing ASC-to-chondrocyte seeding ratios. CONCLUSIONS: These findings provide insight into the mechanisms underlying clinical ASC therapies and signifies that IFPD ASCs pre-conditioned by chondrocyte co-culture may have improved chondrogenic potential for cartilage repair. This model can help further understand IFPD ASCs in chondral and osteochondral repair and the chondrogenic pathways involved. Video Abstract

The use of three-dimensional printing technology in orthopaedic surgery: A review

Three-dimensional (3-D) printing or additive manufacturing, an advanced technology that 3-D physical models are created, has been wildly applied in medical industries, including cardiothoracic surgery, cranio-maxillo-facial surgery and orthopaedic surgery. The physical models made by 3-D printing technology give surgeons a realistic impression of complex structures, allowing surgical planning and simulation before operations. In orthopaedic surgery, this technique is mainly applied in surgical planning especially revision and reconstructive surgeries, making patient-specific instruments or implants, and bone tissue engineering. This article reviews this technology and its application in orthopaedic surgery.published_or_final_versio

Arteriovenous grafts for hemodialysis: a retrospective study from a local urologcial centre

Oral (Free Paper) Session III - BPH and Dialysis Surgery: OP.3-5香港泌尿外科學會OBJECTIVE:Arteriovenous grafts (AVGs) are indicated in hemodialysis patients who have failed arteriovenous fistulae, unsuitable vessels or exhausted superficial veins. The aim of this clinical audit is to evaluate the outcomes of AVG creation in a local urological centre and to compare the results with international ...published_or_final_versionThe 17th Annual Scientific Meeting of the Hong Kong Urological Association, Hong Kong, 6 November 2011. In Program Book, 2011, p. 4

Assessing the removal of organic micro-pollutants from anaerobic membrane bioreactor effluent by fertilizer-drawn forward osmosis

© 2017 Elsevier B.V. In this study, the behavior of organic micro-pollutants (OMPs) transport including membrane fouling was assessed in fertilizer-drawn forward osmosis (FDFO) during treatment of the anaerobic membrane bioreactor (AnMBR) effluent. The flux decline was negligible when the FO membrane was oriented with active layer facing feed solution (AL-FS) while severe flux decline was observed with active layer facing draw solution (AL-DS) with di-ammonium phosphate (DAP) fertilizer as DS due to struvite scaling inside the membrane support layer. DAP DS however exhibited the lowest OMPs forward flux or higher OMPs rejection rate compared to other two fertilizers (i.e., mono-ammonium phosphate (MAP) and KCl). MAP and KCl fertilizer DS had higher water fluxes that induced higher external concentration polarization (ECP) and enhanced OMPs flux through the FO membrane. Under the AL-DS mode of membrane orientation, OMPs transport was further increased with MAP and KCl as DS due to enhanced concentrative internal concentration polarization while with DAP the internal scaling enhanced mass transfer resistance thereby lowering OMPs flux. Physical or hydraulic cleaning could successfully recover water flux for FO membranes operated under the AL-FS mode but only partial flux recovery was observed for membranes operated under AL-DS mode because of internal scaling and fouling in the support layer. Osmotic backwashing could however significantly improve the cleaning efficiency

Understanding and promoting oral health of Indonesian domestic helpers in Hong Kong

Includes bibliographical references (p. 44).published_or_final_versio

An inhomogeneous toy-model of the quantum gravity with explicitly evolvable observables

An inhomogeneous (1+1)-dimensional model of the quantum gravity is considered. It is found, that this model corresponds to a string propagating against some curved background space. The quantization scheme including the Wheeler-DeWitt equation and the "particle on a sphere" type of the gauge condition is suggested. In the quantization scheme considered, the "problem of time" is solved by building of the quasi-Heisenberg operators acting in a space of solutions of the Wheeler-DeWitt equation and the normalization of the wave function corresponds to the Klein-Gordon type. To analyze the physical consequences of the scheme, a (1+1)-dimensional background space is considered for which a classical solution is found and quantized. The obtained estimations show the way to solution of the cosmological constant problem, which consists in compensation of the zero-point oscillations of the matter fields by the quantum oscillations of the scale factor. Along with such a compensation, a slow global evolution of a background corresponding to an universe expansion exists.Comment: 18 page

Ripple Texturing of Suspended Graphene Atomic Membranes

Graphene is the nature's thinnest elastic membrane, with exceptional mechanical and electrical properties. We report the direct observation and creation of one-dimensional (1D) and 2D periodic ripples in suspended graphene sheets, using spontaneously and thermally induced longitudinal strains on patterned substrates, with control over their orientations and wavelengths. We also provide the first measurement of graphene's thermal expansion coefficient, which is anomalously large and negative, ~ -7x10^-6 K^-1 at 300K. Our work enables novel strain-based engineering of graphene devices.Comment: 15 pages, 4 figure